ZBT22.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT22.H12INVITRO.0.SM.B
Gene (human)	ZBTB22 (GeneCards)
Gene synonyms (human)	BING1, ZBTB22A, ZNF297
Gene (mouse)	Zbtb22
Gene synonyms (mouse)	Bing1, Zfp297, Znf297
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	nRWKCACTAYhRTdGTGv
GC content	41.79%
Information content (bits; total / per base)	18.301 / 1.017
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	5235

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.943	0.936	0.83	0.82	0.712	0.717
Overall, 2 experiments	best	0.966	0.959	0.884	0.867	0.766	0.762
Methyl HT-SELEX, 1 experiments	median	0.921	0.912	0.776	0.773	0.657	0.672
Methyl HT-SELEX, 1 experiments	best	0.921	0.912	0.776	0.773	0.657	0.672
Non-Methyl HT-SELEX, 1 experiments	median	0.966	0.959	0.884	0.867	0.766	0.762
Non-Methyl HT-SELEX, 1 experiments	best	0.966	0.959	0.884	0.867	0.766	0.762

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Other with up to three adjacent zinc fingers {2.3.2} (TFClass)
TF subfamily	BTB-POZ {2.3.2.1} (TFClass)
TFClass ID	TFClass: 2.3.2.1.6
HGNC	HGNC:13085
MGI	MGI:1931870
EntrezGene (human)	GeneID:9278 (SSTAR profile)
EntrezGene (mouse)	GeneID:81630 (SSTAR profile)
UniProt ID (human)	ZBT22_HUMAN
UniProt ID (mouse)	ZBT22_MOUSE
UniProt AC (human)	O15209 (TFClass)
UniProt AC (mouse)	Q9Z0G7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZBT22.H12INVITRO.0.SM.B.pcm
PWM	ZBT22.H12INVITRO.0.SM.B.pwm
PFM	ZBT22.H12INVITRO.0.SM.B.pfm
Alignment	ZBT22.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	ZBT22.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	ZBT22.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	ZBT22.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	ZBT22.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	ZBT22.H12INVITRO.0.SM.B_homer_format_0.001.txt ZBT22.H12INVITRO.0.SM.B_homer_format_0.0005.txt ZBT22.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1124.25	1113.25	1347.25	1650.25
02	1110.0	197.0	2974.0	954.0
03	1012.0	787.0	80.0	3356.0
04	18.0	1.0	2085.0	3131.0
05	0.0	5235.0	0.0	0.0
06	5234.0	1.0	0.0	0.0
07	0.0	5235.0	0.0	0.0
08	575.0	287.0	91.0	4282.0
09	5225.0	8.0	1.0	1.0
10	8.0	1387.0	536.0	3304.0
11	1221.0	835.0	538.0	2641.0
12	2741.0	445.0	2012.0	37.0
13	238.0	172.0	214.0	4611.0
14	2409.0	369.0	798.0	1659.0
15	227.0	232.0	4596.0	180.0
16	169.0	131.0	458.0	4477.0
17	102.75	205.75	4510.75	415.75
18	2286.0	1918.0	578.0	453.0

PFM

	A	C	G	T
01	0.215	0.213	0.257	0.315
02	0.212	0.038	0.568	0.182
03	0.193	0.15	0.015	0.641
04	0.003	0.0	0.398	0.598
05	0.0	1.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.0	1.0	0.0	0.0
08	0.11	0.055	0.017	0.818
09	0.998	0.002	0.0	0.0
10	0.002	0.265	0.102	0.631
11	0.233	0.16	0.103	0.504
12	0.524	0.085	0.384	0.007
13	0.045	0.033	0.041	0.881
14	0.46	0.07	0.152	0.317
15	0.043	0.044	0.878	0.034
16	0.032	0.025	0.087	0.855
17	0.02	0.039	0.862	0.079
18	0.437	0.366	0.11	0.087

PWM

	A	C	G	T
01	-0.152	-0.162	0.029	0.232
02	-0.164	-1.884	0.82	-0.316
03	-0.257	-0.508	-2.77	0.941
04	-4.176	-6.034	0.465	0.871
05	-6.417	1.385	-6.417	-6.417
06	1.385	-6.034	-6.417	-6.417
07	-6.417	1.385	-6.417	-6.417
08	-0.82	-1.512	-2.644	1.184
09	1.383	-4.862	-6.034	-6.034
10	-4.862	0.058	-0.89	0.925
11	-0.069	-0.448	-0.887	0.701
12	0.738	-1.076	0.429	-3.511
13	-1.697	-2.019	-1.803	1.258
14	0.609	-1.262	-0.494	0.237
15	-1.744	-1.723	1.255	-1.974
16	-2.036	-2.287	-1.047	1.229
17	-2.526	-1.841	1.236	-1.143
18	0.557	0.382	-0.815	-1.058

Standard thresholds

P-value	Threshold
0.001	-0.22619
0.0005	1.49476
0.0001	5.01156