ZBT18.H12RSNP.0.PSM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT18.H12RSNP.0.PSM.D
Gene (human)	ZBTB18 (GeneCards)
Gene synonyms (human)	RP58, TAZ1, ZNF238
Gene (mouse)	Zbtb18
Gene synonyms (mouse)	Rp58, Zfp238, Znf238
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	11
Consensus	bSCAGhTGYKb
GC content	55.87%
Information content (bits; total / per base)	10.85 / 0.986
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	500

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.825	0.837	0.761	0.779	0.81	0.814	2.946	3.02	231.886	241.056

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.992	0.99	0.898	0.906	0.763	0.79
Overall, 6 experiments	best	1.0	0.999	0.998	0.997	0.971	0.971
Methyl HT-SELEX, 1 experiments	median	0.999	0.998	0.998	0.997	0.971	0.971
Methyl HT-SELEX, 1 experiments	best	0.999	0.998	0.998	0.997	0.971	0.971
Non-Methyl HT-SELEX, 5 experiments	median	0.985	0.982	0.802	0.818	0.656	0.692
Non-Methyl HT-SELEX, 5 experiments	best	1.0	0.999	0.998	0.997	0.888	0.9

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF238-like {2.3.3.16} (TFClass)
TFClass ID	TFClass: 2.3.3.16.1
HGNC	HGNC:13030
MGI	MGI:1353609
EntrezGene (human)	GeneID:10472 (SSTAR profile)
EntrezGene (mouse)	GeneID:30928 (SSTAR profile)
UniProt ID (human)	ZBT18_HUMAN
UniProt ID (mouse)	ZBT18_MOUSE
UniProt AC (human)	Q99592 (TFClass)
UniProt AC (mouse)	Q9WUK6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	ZBT18.H12RSNP.0.PSM.D.pcm
PWM	ZBT18.H12RSNP.0.PSM.D.pwm
PFM	ZBT18.H12RSNP.0.PSM.D.pfm
Alignment	ZBT18.H12RSNP.0.PSM.D.words.tsv
Threshold to P-value map	ZBT18.H12RSNP.0.PSM.D.thr
Motif in other formats
JASPAR format	ZBT18.H12RSNP.0.PSM.D_jaspar_format.txt
MEME format	ZBT18.H12RSNP.0.PSM.D_meme_format.meme
Transfac format	ZBT18.H12RSNP.0.PSM.D_transfac_format.txt
Homer format	ZBT18.H12RSNP.0.PSM.D_homer_format_0.001.txt ZBT18.H12RSNP.0.PSM.D_homer_format_0.0005.txt ZBT18.H12RSNP.0.PSM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	37.0	72.0	140.0	251.0
02	58.0	368.0	72.0	2.0
03	4.0	492.0	1.0	3.0
04	486.0	6.0	3.0	5.0
05	2.0	7.0	433.0	58.0
06	224.0	184.0	15.0	77.0
07	2.0	5.0	54.0	439.0
08	1.0	12.0	474.0	13.0
09	61.0	134.0	6.0	299.0
10	30.0	25.0	225.0	220.0
11	45.0	133.0	212.0	110.0

PFM

	A	C	G	T
01	0.074	0.144	0.28	0.502
02	0.116	0.736	0.144	0.004
03	0.008	0.984	0.002	0.006
04	0.972	0.012	0.006	0.01
05	0.004	0.014	0.866	0.116
06	0.448	0.368	0.03	0.154
07	0.004	0.01	0.108	0.878
08	0.002	0.024	0.948	0.026
09	0.122	0.268	0.012	0.598
10	0.06	0.05	0.45	0.44
11	0.09	0.266	0.424	0.22

PWM

	A	C	G	T
01	-1.189	-0.543	0.112	0.691
02	-0.754	1.072	-0.543	-3.573
03	-3.126	1.361	-3.903	-3.325
04	1.349	-2.819	-3.325	-2.961
05	-3.573	-2.694	1.234	-0.754
06	0.578	0.383	-2.034	-0.477
07	-3.573	-2.961	-0.823	1.247
08	-3.903	-2.234	1.324	-2.163
09	-0.705	0.069	-2.819	0.865
10	-1.389	-1.561	0.582	0.56
11	-1.0	0.061	0.523	-0.126

Standard thresholds

P-value	Threshold
0.001	4.53868
0.0005	5.48269
0.0001	7.413635