ZBT14.H12INVIVO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT14.H12INVIVO.1.S.B
Gene (human)	ZBTB14 (GeneCards)
Gene synonyms (human)	ZFP161, ZNF478
Gene (mouse)	Zbtb14
Gene synonyms (mouse)	Zfp-5, Zfp161, Zfp5
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	17
Consensus	ndYGCGCGTGCACGhKn
GC content	68.89%
Information content (bits; total / per base)	19.776 / 1.163
Data sources	HT-SELEX
Aligned words	6875

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.881	0.915	0.786	0.843	0.709	0.762	2.2	2.481	61.886	108.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.847	0.843	0.709	0.713	0.618	0.632
Non-Methyl HT-SELEX, 2 experiments	best	0.965	0.965	0.78	0.794	0.653	0.68

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.1
HGNC	HGNC:12860
MGI	MGI:1195345
EntrezGene (human)	GeneID:7541 (SSTAR profile)
EntrezGene (mouse)	GeneID:22666 (SSTAR profile)
UniProt ID (human)	ZBT14_HUMAN
UniProt ID (mouse)	ZBT14_MOUSE
UniProt AC (human)	O43829 (TFClass)
UniProt AC (mouse)	Q08376 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	ZBT14.H12INVIVO.1.S.B.pcm
PWM	ZBT14.H12INVIVO.1.S.B.pwm
PFM	ZBT14.H12INVIVO.1.S.B.pfm
Alignment	ZBT14.H12INVIVO.1.S.B.words.tsv
Threshold to P-value map	ZBT14.H12INVIVO.1.S.B.thr
Motif in other formats
JASPAR format	ZBT14.H12INVIVO.1.S.B_jaspar_format.txt
MEME format	ZBT14.H12INVIVO.1.S.B_meme_format.meme
Transfac format	ZBT14.H12INVIVO.1.S.B_transfac_format.txt
Homer format	ZBT14.H12INVIVO.1.S.B_homer_format_0.001.txt ZBT14.H12INVIVO.1.S.B_homer_format_0.0005.txt ZBT14.H12INVIVO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1878.25	2032.25	1484.25	1480.25
02	2971.5	489.5	2664.5	749.5
03	589.0	1569.0	620.0	4097.0
04	135.0	84.0	6572.0	84.0
05	90.0	6634.0	75.0	76.0
06	99.0	42.0	6602.0	132.0
07	34.0	6746.0	50.0	45.0
08	35.0	8.0	6819.0	13.0
09	16.0	220.0	136.0	6503.0
10	76.0	46.0	6417.0	336.0
11	114.0	6646.0	72.0	43.0
12	5932.0	561.0	189.0	193.0
13	82.0	6229.0	104.0	460.0
14	263.0	128.0	6347.0	137.0
15	846.0	2263.0	330.0	3436.0
16	631.5	596.5	4661.5	985.5
17	2260.75	1399.75	1672.75	1541.75

PFM

	A	C	G	T
01	0.273	0.296	0.216	0.215
02	0.432	0.071	0.388	0.109
03	0.086	0.228	0.09	0.596
04	0.02	0.012	0.956	0.012
05	0.013	0.965	0.011	0.011
06	0.014	0.006	0.96	0.019
07	0.005	0.981	0.007	0.007
08	0.005	0.001	0.992	0.002
09	0.002	0.032	0.02	0.946
10	0.011	0.007	0.933	0.049
11	0.017	0.967	0.01	0.006
12	0.863	0.082	0.027	0.028
13	0.012	0.906	0.015	0.067
14	0.038	0.019	0.923	0.02
15	0.123	0.329	0.048	0.5
16	0.092	0.087	0.678	0.143
17	0.329	0.204	0.243	0.224

PWM

	A	C	G	T
01	0.089	0.167	-0.146	-0.149
02	0.547	-1.253	0.438	-0.828
03	-1.068	-0.091	-1.017	0.868
04	-2.529	-2.994	1.34	-2.994
05	-2.927	1.35	-3.104	-3.091
06	-2.833	-3.662	1.345	-2.551
07	-3.861	1.366	-3.495	-3.596
08	-3.834	-5.127	1.377	-4.729
09	-4.549	-2.047	-2.522	1.33
10	-3.091	-3.575	1.316	-1.627
11	-2.695	1.351	-3.144	-3.639
12	1.238	-1.117	-2.197	-2.177
13	-3.017	1.287	-2.785	-1.315
14	-1.87	-2.581	1.305	-2.515
15	-0.708	0.275	-1.645	0.692
16	-0.999	-1.056	0.997	-0.555
17	0.274	-0.205	-0.027	-0.109

Standard thresholds

P-value	Threshold
0.001	0.08646
0.0005	1.53361
0.0001	4.59531