ZBT14.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT14.H12INVITRO.1.S.B
Gene (human)	ZBTB14 (GeneCards)
Gene synonyms (human)	ZFP161, ZNF478
Gene (mouse)	Zbtb14
Gene synonyms (mouse)	Zfp-5, Zfp161, Zfp5
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	16
Consensus	dYGCGCGTGCACGhKn
GC content	70.74%
Information content (bits; total / per base)	20.891 / 1.306
Data sources	HT-SELEX
Aligned words	903

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.869	0.9	0.773	0.824	0.701	0.752	2.135	2.397	57.62	103.066

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.855	0.848	0.726	0.723	0.635	0.643
Non-Methyl HT-SELEX, 2 experiments	best	0.966	0.966	0.794	0.803	0.669	0.69

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.1
HGNC	HGNC:12860
MGI	MGI:1195345
EntrezGene (human)	GeneID:7541 (SSTAR profile)
EntrezGene (mouse)	GeneID:22666 (SSTAR profile)
UniProt ID (human)	ZBT14_HUMAN
UniProt ID (mouse)	ZBT14_MOUSE
UniProt AC (human)	O43829 (TFClass)
UniProt AC (mouse)	Q08376 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	ZBT14.H12INVITRO.1.S.B.pcm
PWM	ZBT14.H12INVITRO.1.S.B.pwm
PFM	ZBT14.H12INVITRO.1.S.B.pfm
Alignment	ZBT14.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	ZBT14.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	ZBT14.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	ZBT14.H12INVITRO.1.S.B_meme_format.meme
Transfac format	ZBT14.H12INVITRO.1.S.B_transfac_format.txt
Homer format	ZBT14.H12INVITRO.1.S.B_homer_format_0.001.txt ZBT14.H12INVITRO.1.S.B_homer_format_0.0005.txt ZBT14.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	323.75	99.75	350.75	128.75
02	60.0	228.0	61.0	554.0
03	35.0	8.0	839.0	21.0
04	1.0	899.0	1.0	2.0
05	4.0	3.0	896.0	0.0
06	0.0	903.0	0.0	0.0
07	1.0	0.0	902.0	0.0
08	0.0	14.0	0.0	889.0
09	8.0	0.0	834.0	61.0
10	9.0	882.0	9.0	3.0
11	814.0	67.0	19.0	3.0
12	8.0	815.0	7.0	73.0
13	19.0	23.0	833.0	28.0
14	126.0	355.0	35.0	387.0
15	75.75	79.75	647.75	99.75
16	325.0	215.0	194.0	169.0

PFM

	A	C	G	T
01	0.359	0.11	0.388	0.143
02	0.066	0.252	0.068	0.614
03	0.039	0.009	0.929	0.023
04	0.001	0.996	0.001	0.002
05	0.004	0.003	0.992	0.0
06	0.0	1.0	0.0	0.0
07	0.001	0.0	0.999	0.0
08	0.0	0.016	0.0	0.984
09	0.009	0.0	0.924	0.068
10	0.01	0.977	0.01	0.003
11	0.901	0.074	0.021	0.003
12	0.009	0.903	0.008	0.081
13	0.021	0.025	0.922	0.031
14	0.14	0.393	0.039	0.429
15	0.084	0.088	0.717	0.11
16	0.36	0.238	0.215	0.187

PWM

	A	C	G	T
01	0.358	-0.807	0.438	-0.556
02	-1.305	0.01	-1.289	0.893
03	-1.824	-3.155	1.307	-2.305
04	-4.433	1.376	-4.433	-4.118
05	-3.686	-3.879	1.373	-4.895
06	-4.895	1.381	-4.895	-4.895
07	-4.433	-4.895	1.38	-4.895
08	-4.895	-2.673	-4.895	1.365
09	-3.155	-4.895	1.301	-1.289
10	-3.057	1.357	-3.057	-3.879
11	1.277	-1.197	-2.397	-3.879
12	-3.155	1.278	-3.263	-1.113
13	-2.397	-2.22	1.3	-2.036
14	-0.577	0.45	-1.824	0.536
15	-1.077	-1.027	1.049	-0.807
16	0.362	-0.048	-0.15	-0.287

Standard thresholds

P-value	Threshold
0.001	-1.26319
0.0005	0.35866
0.0001	3.79231