MotifXBP1.H12CORE.1.M.B
Gene (human)XBP1
(GeneCards)
Gene synonyms (human)TREB5, XBP2
Gene (mouse)Xbp1
Gene synonyms (mouse)Treb5
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusdbGRTGACGYvdSn
GC content55.49%
Information content (bits; total / per base)11.35 / 0.811
Data sourcesMethyl-HT-SELEX
Aligned words1983

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (19) 0.682 0.72 0.577 0.624 0.668 0.698 1.993 2.175 81.959 104.569
Mouse 5 (34) 0.721 0.759 0.618 0.663 0.69 0.72 2.18 2.548 72.512 130.432

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.938 0.904 0.897 0.857 0.827 0.791
best 0.98 0.967 0.956 0.937 0.905 0.88
Methyl HT-SELEX, 2 experiments median 0.953 0.926 0.922 0.889 0.865 0.832
best 0.976 0.962 0.954 0.933 0.905 0.88
Non-Methyl HT-SELEX, 4 experiments median 0.901 0.885 0.784 0.779 0.7 0.702
best 0.98 0.967 0.956 0.937 0.899 0.876

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.707 0.102 0.643 0.458
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyXBP1-related {1.1.5} (TFClass)
TF subfamily {1.1.5.0} (TFClass)
TFClass IDTFClass: 1.1.5.0.1
HGNCHGNC:12801
MGIMGI:98970
EntrezGene (human)GeneID:7494
(SSTAR profile)
EntrezGene (mouse)GeneID:22433
(SSTAR profile)
UniProt ID (human)XBP1_HUMAN
UniProt ID (mouse)XBP1_MOUSE
UniProt AC (human)P17861
(TFClass)
UniProt AC (mouse)O35426
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 5 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01816.75223.75696.75245.75
02215.25428.25636.25703.25
03105.0247.01583.048.0
041260.0306.0407.010.0
052.06.014.01961.0
0617.00.01949.017.0
071981.00.02.00.0
080.01621.0103.0259.0
0984.014.01533.0352.0
10211.0670.046.01056.0
11591.0250.0948.0194.0
12427.0263.0743.0550.0
13203.01262.0265.0253.0
14505.25509.25680.25288.25
PFM
ACGT
010.4120.1130.3510.124
020.1090.2160.3210.355
030.0530.1250.7980.024
040.6350.1540.2050.005
050.0010.0030.0070.989
060.0090.00.9830.009
070.9990.00.0010.0
080.00.8170.0520.131
090.0420.0070.7730.178
100.1060.3380.0230.533
110.2980.1260.4780.098
120.2150.1330.3750.277
130.1020.6360.1340.128
140.2550.2570.3430.145
PWM
ACGT
010.498-0.7910.339-0.698
02-0.829-0.1460.2490.349
03-1.538-0.6931.158-2.3
040.93-0.48-0.196-3.734
05-4.849-4.143-3.4441.372
06-3.271-5.5691.366-3.271
071.382-5.569-4.849-5.569
08-5.5691.182-1.557-0.646
09-1.757-3.4441.126-0.341
10-0.8490.3-2.3410.754
110.175-0.6810.646-0.932
12-0.149-0.6310.4030.103
13-0.8870.932-0.623-0.669
140.0190.0270.315-0.54
Standard thresholds
P-value Threshold
0.001 4.38511
0.0005 5.42801
0.0001 7.38831