MotifXBP1.H12CORE.0.PS.A
Gene (human)XBP1
(GeneCards)
Gene synonyms (human)TREB5, XBP2
Gene (mouse)Xbp1
Gene synonyms (mouse)Treb5
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length12
ConsensusnvvWKACGTRdh
GC content55.2%
Information content (bits; total / per base)9.986 / 0.832
Data sourcesChIP-Seq + HT-SELEX
Aligned words9930

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (19) 0.756 0.83 0.686 0.739 0.693 0.785 2.484 2.842 151.31 193.77
Mouse 5 (34) 0.836 0.909 0.764 0.848 0.771 0.866 2.985 3.392 148.068 354.469

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.936 0.922 0.858 0.816 0.807 0.765
best 0.985 0.975 0.969 0.954 0.946 0.923
Methyl HT-SELEX, 2 experiments median 0.904 0.869 0.858 0.816 0.807 0.765
best 0.957 0.937 0.917 0.887 0.869 0.833
Non-Methyl HT-SELEX, 4 experiments median 0.941 0.927 0.839 0.832 0.763 0.761
best 0.985 0.975 0.969 0.954 0.946 0.923

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.849 0.341 0.708 0.512
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyXBP1-related {1.1.5} (TFClass)
TF subfamily {1.1.5.0} (TFClass)
TFClass IDTFClass: 1.1.5.0.1
HGNCHGNC:12801
MGIMGI:98970
EntrezGene (human)GeneID:7494
(SSTAR profile)
EntrezGene (mouse)GeneID:22433
(SSTAR profile)
UniProt ID (human)XBP1_HUMAN
UniProt ID (mouse)XBP1_MOUSE
UniProt AC (human)P17861
(TFClass)
UniProt AC (mouse)O35426
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 5 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012056.752290.752569.753012.75
021688.01577.05117.01548.0
033947.01882.02976.01125.0
041300.0968.0792.06870.0
05393.01136.06982.01419.0
069868.05.056.01.0
0716.09842.031.041.0
08102.022.09725.081.0
09382.0688.0185.08675.0
101081.0786.07386.0677.0
11946.75568.754202.754211.75
121982.04472.01512.01964.0
PFM
ACGT
010.2070.2310.2590.303
020.170.1590.5150.156
030.3970.190.30.113
040.1310.0970.080.692
050.040.1140.7030.143
060.9940.0010.0060.0
070.0020.9910.0030.004
080.010.0020.9790.008
090.0380.0690.0190.874
100.1090.0790.7440.068
110.0950.0570.4230.424
120.20.450.1520.198
PWM
ACGT
01-0.188-0.080.0350.193
02-0.385-0.4530.723-0.472
030.463-0.2770.181-0.79
04-0.646-0.94-1.141.017
05-1.838-0.7811.033-0.559
061.379-5.83-3.752-6.624
07-4.9111.377-4.312-4.05
08-3.171-4.6271.365-3.395
09-1.867-1.281-2.5851.251
10-0.83-1.1481.09-1.297
11-0.962-1.470.5260.528
12-0.2250.588-0.495-0.234
Standard thresholds
P-value Threshold
0.001 4.82941
0.0005 5.708225
0.0001 7.369055