WT1.H12INVITRO.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	WT1.H12INVITRO.1.P.D
Gene (human)	WT1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Wt1
Gene synonyms (mouse)	Wt-1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	21
Consensus	vvvdShGKGGGAGKvdvvvvv
GC content	68.28%
Information content (bits; total / per base)	14.504 / 0.691
Data sources	ChIP-Seq
Aligned words	995

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.642	0.862	0.47	0.724	0.588	0.954	1.862	4.862	12.643	197.523
Mouse	3 (17)	0.856	0.885	0.693	0.757	0.932	0.963	4.541	5.472	198.244	249.009

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.21
HGNC	HGNC:12796
MGI	MGI:98968
EntrezGene (human)	GeneID:7490 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	WT1_HUMAN
UniProt ID (mouse)	WT1_MOUSE
UniProt AC (human)	P19544 (TFClass)
UniProt AC (mouse)	P22561 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 3 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	WT1.H12INVITRO.1.P.D.pcm
PWM	WT1.H12INVITRO.1.P.D.pwm
PFM	WT1.H12INVITRO.1.P.D.pfm
Alignment	WT1.H12INVITRO.1.P.D.words.tsv
Threshold to P-value map	WT1.H12INVITRO.1.P.D.thr
Motif in other formats
JASPAR format	WT1.H12INVITRO.1.P.D_jaspar_format.txt
MEME format	WT1.H12INVITRO.1.P.D_meme_format.meme
Transfac format	WT1.H12INVITRO.1.P.D_transfac_format.txt
Homer format	WT1.H12INVITRO.1.P.D_homer_format_0.001.txt WT1.H12INVITRO.1.P.D_homer_format_0.0005.txt WT1.H12INVITRO.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	184.0	200.0	515.0	96.0
02	304.0	193.0	394.0	104.0
03	283.0	218.0	412.0	82.0
04	178.0	135.0	322.0	360.0
05	70.0	110.0	787.0	28.0
06	196.0	400.0	61.0	338.0
07	34.0	4.0	930.0	27.0
08	63.0	6.0	570.0	356.0
09	116.0	2.0	869.0	8.0
10	2.0	6.0	984.0	3.0
11	6.0	2.0	986.0	1.0
12	881.0	85.0	9.0	20.0
13	22.0	5.0	953.0	15.0
14	97.0	15.0	708.0	175.0
15	323.0	176.0	429.0	67.0
16	298.0	124.0	431.0	142.0
17	269.0	198.0	420.0	108.0
18	253.0	199.0	408.0	135.0
19	177.0	180.0	527.0	111.0
20	213.0	180.0	459.0	143.0
21	221.0	233.0	423.0	118.0

PFM

	A	C	G	T
01	0.185	0.201	0.518	0.096
02	0.306	0.194	0.396	0.105
03	0.284	0.219	0.414	0.082
04	0.179	0.136	0.324	0.362
05	0.07	0.111	0.791	0.028
06	0.197	0.402	0.061	0.34
07	0.034	0.004	0.935	0.027
08	0.063	0.006	0.573	0.358
09	0.117	0.002	0.873	0.008
10	0.002	0.006	0.989	0.003
11	0.006	0.002	0.991	0.001
12	0.885	0.085	0.009	0.02
13	0.022	0.005	0.958	0.015
14	0.097	0.015	0.712	0.176
15	0.325	0.177	0.431	0.067
16	0.299	0.125	0.433	0.143
17	0.27	0.199	0.422	0.109
18	0.254	0.2	0.41	0.136
19	0.178	0.181	0.53	0.112
20	0.214	0.181	0.461	0.144
21	0.222	0.234	0.425	0.119

PWM

	A	C	G	T
01	-0.299	-0.216	0.724	-0.941
02	0.199	-0.252	0.457	-0.863
03	0.128	-0.131	0.502	-1.096
04	-0.332	-0.605	0.257	0.368
05	-1.251	-0.807	1.147	-2.131
06	-0.236	0.472	-1.385	0.305
07	-1.947	-3.778	1.314	-2.166
08	-1.353	-3.479	0.825	0.356
09	-0.755	-4.208	1.246	-3.249
10	-4.208	-3.479	1.37	-3.97
11	-3.479	-4.208	1.372	-4.521
12	1.26	-1.061	-3.151	-2.445
13	-2.357	-3.617	1.338	-2.706
14	-0.931	-2.706	1.042	-0.349
15	0.26	-0.343	0.542	-1.293
16	0.18	-0.689	0.547	-0.555
17	0.078	-0.226	0.521	-0.825
18	0.017	-0.221	0.492	-0.605
19	-0.338	-0.321	0.747	-0.798
20	-0.154	-0.321	0.609	-0.549
21	-0.117	-0.065	0.528	-0.738

Standard thresholds

P-value	Threshold
0.001	3.17576
0.0005	4.33326
0.0001	6.73041