MotifVSX2.H12CORE.1.S.B
Gene (human)VSX2
(GeneCards)
Gene synonyms (human)CHX10, HOX10
Gene (mouse)Vsx2
Gene synonyms (mouse)Chx10
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length17
ConsensusnvYTAATTAGYhhhhhd
GC content32.15%
Information content (bits; total / per base)16.856 / 0.992
Data sourcesHT-SELEX
Aligned words2345

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.975 0.981 0.961 0.974 0.973 0.978 5.521 5.621 355.886 420.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.997 0.994 0.993 0.99 0.978 0.972
best 0.998 0.997 0.997 0.996 0.994 0.991
Methyl HT-SELEX, 2 experiments median 0.99 0.983 0.985 0.976 0.97 0.958
best 0.998 0.997 0.997 0.996 0.994 0.991
Non-Methyl HT-SELEX, 4 experiments median 0.997 0.994 0.993 0.99 0.978 0.972
best 0.997 0.996 0.994 0.99 0.987 0.981

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.928 0.285 0.922 0.599
batch 2 0.857 0.702 0.858 0.646
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyVSX {3.1.3.28} (TFClass)
TFClass IDTFClass: 3.1.3.28.2
HGNCHGNC:1975
MGIMGI:88401
EntrezGene (human)GeneID:338917
(SSTAR profile)
EntrezGene (mouse)GeneID:12677
(SSTAR profile)
UniProt ID (human)VSX2_HUMAN
UniProt ID (mouse)VSX2_MOUSE
UniProt AC (human)P58304
(TFClass)
UniProt AC (mouse)Q61412
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01534.25684.25726.25400.25
02545.5442.51165.5191.5
0353.01582.0300.0410.0
042.046.00.02297.0
052345.00.00.00.0
062345.00.00.00.0
070.00.00.02345.0
080.00.00.02345.0
092321.00.024.00.0
10144.063.02134.04.0
1149.01693.0156.0447.0
12306.0973.0271.0795.0
131226.0388.0178.0553.0
141277.0372.0156.0540.0
15687.0292.0125.01241.0
16692.0269.0143.01241.0
17933.5263.5369.5778.5
PFM
ACGT
010.2280.2920.310.171
020.2330.1890.4970.082
030.0230.6750.1280.175
040.0010.020.00.98
051.00.00.00.0
061.00.00.00.0
070.00.00.01.0
080.00.00.01.0
090.990.00.010.0
100.0610.0270.910.002
110.0210.7220.0670.191
120.130.4150.1160.339
130.5230.1650.0760.236
140.5450.1590.0670.23
150.2930.1250.0530.529
160.2950.1150.0610.529
170.3980.1120.1580.332
PWM
ACGT
01-0.0930.1540.214-0.38
02-0.072-0.280.686-1.112
03-2.3710.991-0.667-0.356
04-5.006-2.507-5.7141.363
051.384-5.714-5.714-5.714
061.384-5.714-5.714-5.714
07-5.714-5.714-5.7141.384
08-5.714-5.714-5.7141.384
091.374-5.714-3.121-5.714
10-1.394-2.2041.29-4.595
11-2.4461.058-1.315-0.27
12-0.6470.505-0.7680.304
130.736-0.411-1.184-0.058
140.777-0.453-1.315-0.082
150.158-0.694-1.5330.748
160.165-0.775-1.4010.748
170.464-0.796-0.460.283
Standard thresholds
P-value Threshold
0.001 0.25441
0.0005 1.91141
0.0001 5.38046