MotifVENTX.H12INVIVO.1.S.D
Gene (human)VENTX
(GeneCards)
Gene synonyms (human)HPX42B, VENTX2
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length18
ConsensusnnhdMATTTGCATAhdhd
GC content32.53%
Information content (bits; total / per base)15.662 / 0.87
Data sourcesHT-SELEX
Aligned words2479

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.744 0.677 0.694 0.641 0.643 0.608
best 0.998 0.996 0.994 0.991 0.975 0.968
Methyl HT-SELEX, 1 experiments median 0.761 0.694 0.709 0.654 0.656 0.619
best 0.761 0.694 0.709 0.654 0.656 0.619
Non-Methyl HT-SELEX, 3 experiments median 0.726 0.661 0.678 0.627 0.63 0.597
best 0.998 0.996 0.994 0.991 0.975 0.968

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.607 0.006 0.666 0.44
batch 2 0.533 0.027 0.519 0.304
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyVENTX {3.1.2.23} (TFClass)
TFClass IDTFClass: 3.1.2.23.1
HGNCHGNC:13639
MGI
EntrezGene (human)GeneID:27287
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)VENTX_HUMAN
UniProt ID (mouse)
UniProt AC (human)O95231
(TFClass)
UniProt AC (mouse)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01649.5593.5595.5640.5
02683.5749.5579.5466.5
03317.01046.0315.0801.0
04540.0151.0510.01278.0
051505.0578.0223.0173.0
062094.068.095.0222.0
0713.024.08.02434.0
08575.09.03.01892.0
09441.03.00.02035.0
1021.07.02437.014.0
1133.02414.015.017.0
122390.024.035.030.0
1382.029.010.02358.0
142114.030.0243.092.0
15737.0497.083.01162.0
16424.0246.0891.0918.0
17340.51012.5312.5813.5
181230.25297.25379.25572.25
PFM
ACGT
010.2620.2390.240.258
020.2760.3020.2340.188
030.1280.4220.1270.323
040.2180.0610.2060.516
050.6070.2330.090.07
060.8450.0270.0380.09
070.0050.010.0030.982
080.2320.0040.0010.763
090.1780.0010.00.821
100.0080.0030.9830.006
110.0130.9740.0060.007
120.9640.010.0140.012
130.0330.0120.0040.951
140.8530.0120.0980.037
150.2970.20.0330.469
160.1710.0990.3590.37
170.1370.4080.1260.328
180.4960.120.1530.231
PWM
ACGT
010.047-0.043-0.040.033
020.0980.19-0.067-0.283
03-0.6670.522-0.6740.256
04-0.137-1.402-0.1940.722
050.885-0.07-1.017-1.268
061.215-2.185-1.858-1.021
07-3.727-3.176-4.1341.366
08-0.075-4.039-4.8321.114
09-0.339-4.832-5.7631.187
10-3.299-4.241.367-3.663
11-2.8781.357-3.602-3.49
121.347-3.176-2.823-2.968
13-2.002-3.0-3.9511.334
141.225-2.968-0.931-1.89
150.173-0.22-1.990.627
16-0.378-0.9190.3620.392
17-0.5960.49-0.6820.271
180.684-0.731-0.489-0.079
Standard thresholds
P-value Threshold
0.001 2.30891
0.0005 3.59281
0.0001 6.27566