MotifVENTX.H12INVITRO.0.SM.B
Gene (human)VENTX
(GeneCards)
Gene synonyms (human)HPX42B, VENTX2
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnhvATTARbn
GC content35.91%
Information content (bits; total / per base)8.493 / 0.849
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9580

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.953 0.933 0.905 0.877 0.858 0.827
best 0.987 0.981 0.97 0.957 0.941 0.92
Methyl HT-SELEX, 1 experiments median 0.987 0.981 0.97 0.957 0.941 0.92
best 0.987 0.981 0.97 0.957 0.941 0.92
Non-Methyl HT-SELEX, 3 experiments median 0.928 0.9 0.852 0.817 0.787 0.752
best 0.978 0.966 0.958 0.938 0.929 0.902

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.935 0.138 0.915 0.52
batch 2 0.783 0.208 0.752 0.49
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyVENTX {3.1.2.23} (TFClass)
TFClass IDTFClass: 3.1.2.23.1
HGNCHGNC:13639
MGI
EntrezGene (human)GeneID:27287
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)VENTX_HUMAN
UniProt ID (mouse)
UniProt AC (human)O95231
(TFClass)
UniProt AC (mouse)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012378.52798.52390.52012.5
02883.54115.5766.53814.5
033139.03754.02417.0270.0
048772.0350.0394.064.0
050.01.00.09579.0
060.02.01.09577.0
079145.0386.027.022.0
083644.0796.04555.0585.0
09784.254483.252224.252088.25
102709.751803.753138.751927.75
PFM
ACGT
010.2480.2920.250.21
020.0920.430.080.398
030.3280.3920.2520.028
040.9160.0370.0410.007
050.00.00.01.0
060.00.00.01.0
070.9550.040.0030.002
080.380.0830.4750.061
090.0820.4680.2320.218
100.2830.1880.3280.201
PWM
ACGT
01-0.0070.156-0.002-0.174
02-0.9960.541-1.1370.465
030.270.4490.009-2.175
041.297-1.918-1.8-3.588
05-6.953-6.591-6.9531.385
06-6.953-6.325-6.5911.385
071.339-1.82-4.405-4.592
080.419-1.10.642-1.407
09-1.1140.627-0.074-0.137
100.123-0.2830.27-0.217
Standard thresholds
P-value Threshold
0.001 5.383985
0.0005 6.22016
0.0001 7.25935