MotifVDR.H12INVIVO.0.PS.A
Gene (human)VDR
(GeneCards)
Gene synonyms (human)NR1I1
Gene (mouse)Vdr
Gene synonyms (mouse)Nr1i1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length16
ConsensusvRGKYSAnnRRGKKYv
GC content57.66%
Information content (bits; total / per base)11.661 / 0.729
Data sourcesChIP-Seq + HT-SELEX
Aligned words918

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 45 (197) 0.818 0.98 0.77 0.968 0.808 0.97 3.501 5.967 143.131 835.108
Mouse 10 (52) 0.824 0.915 0.765 0.858 0.797 0.908 3.309 4.029 158.293 273.509

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 4 experiments median 0.747 0.744 0.628 0.638 0.563 0.581
best 0.998 0.998 0.972 0.97 0.802 0.826
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyVDR (NR1I) {2.1.2.4} (TFClass)
TFClass IDTFClass: 2.1.2.4.1
HGNCHGNC:12679
MGIMGI:103076
EntrezGene (human)GeneID:7421
(SSTAR profile)
EntrezGene (mouse)GeneID:22337
(SSTAR profile)
UniProt ID (human)VDR_HUMAN
UniProt ID (mouse)VDR_MOUSE
UniProt AC (human)P11473
(TFClass)
UniProt AC (mouse)P48281
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 45 human, 10 mouse
HT-SELEX 4
Methyl-HT-SELEX 0
PCM
ACGT
01260.0117.0461.080.0
02452.019.0431.016.0
0343.05.0813.057.0
0449.08.0664.0197.0
0510.0146.0130.0632.0
0636.0703.092.087.0
07739.024.0121.034.0
08133.0284.0281.0220.0
09248.0190.0136.0344.0
10122.0100.0662.034.0
11375.033.0501.09.0
1244.06.0859.09.0
1323.029.0344.0522.0
1440.0125.0151.0602.0
1515.0654.060.0189.0
16513.0151.0169.085.0
PFM
ACGT
010.2830.1270.5020.087
020.4920.0210.4690.017
030.0470.0050.8860.062
040.0530.0090.7230.215
050.0110.1590.1420.688
060.0390.7660.10.095
070.8050.0260.1320.037
080.1450.3090.3060.24
090.270.2070.1480.375
100.1330.1090.7210.037
110.4080.0360.5460.01
120.0480.0070.9360.01
130.0250.0320.3750.569
140.0440.1360.1640.656
150.0160.7120.0650.206
160.5590.1640.1840.093
PWM
ACGT
010.124-0.6670.694-1.04
020.674-2.4130.627-2.569
03-1.643-3.541.26-1.371
04-1.517-3.1711.058-0.151
05-2.983-0.448-0.5631.008
06-1.8131.114-0.903-0.958
071.164-2.197-0.634-1.868
08-0.540.2120.201-0.042
090.077-0.187-0.5180.402
10-0.625-0.8211.055-1.868
110.488-1.8960.777-3.073
12-1.621-3.4011.314-3.073
13-2.236-2.0190.4020.818
14-1.713-0.601-0.4150.96
15-2.6281.042-1.321-0.193
160.8-0.415-0.303-0.981
Standard thresholds
P-value Threshold
0.001 4.34171
0.0005 5.24486
0.0001 7.12451