MotifVAX2.H12CORE.0.SM.B
Gene (human)VAX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Vax2
Gene synonyms (mouse)Vex
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnvvTMATTARbbn
GC content39.14%
Information content (bits; total / per base)11.954 / 0.92
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9048

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.974 0.959 0.946 0.923 0.875 0.84
best 0.987 0.977 0.978 0.964 0.958 0.939
Methyl HT-SELEX, 2 experiments median 0.963 0.939 0.947 0.918 0.917 0.886
best 0.987 0.977 0.978 0.964 0.958 0.939
Non-Methyl HT-SELEX, 4 experiments median 0.974 0.959 0.946 0.923 0.868 0.84
best 0.985 0.974 0.975 0.96 0.955 0.935

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.994 0.968 0.961 0.64
batch 2 0.719 0.555 0.751 0.529
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyVAX {3.1.2.22} (TFClass)
TFClass IDTFClass: 3.1.2.22.2
HGNCHGNC:12661
MGIMGI:1346018
EntrezGene (human)GeneID:25806
(SSTAR profile)
EntrezGene (mouse)GeneID:24113
(SSTAR profile)
UniProt ID (human)VAX2_HUMAN
UniProt ID (mouse)VAX2_MOUSE
UniProt AC (human)Q9UIW0
(TFClass)
UniProt AC (mouse)Q9WTP9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012363.251939.252905.251840.25
021475.253056.253294.251222.25
03984.03220.04165.0679.0
0433.01054.027.07934.0
055659.03319.058.012.0
069048.00.00.00.0
070.00.00.09048.0
080.00.00.09048.0
099048.00.00.00.0
102564.0920.05459.0105.0
11296.03930.02209.02613.0
121487.251857.254066.251637.25
132162.252401.252160.252324.25
PFM
ACGT
010.2610.2140.3210.203
020.1630.3380.3640.135
030.1090.3560.460.075
040.0040.1160.0030.877
050.6250.3670.0060.001
061.00.00.00.0
070.00.00.01.0
080.00.00.01.0
091.00.00.00.0
100.2830.1020.6030.012
110.0330.4340.2440.289
120.1640.2050.4490.181
130.2390.2650.2390.257
PWM
ACGT
010.044-0.1540.25-0.206
02-0.4270.3010.376-0.615
03-0.8310.3530.61-1.201
04-4.162-0.763-4.3481.254
050.9160.383-3.626-5.066
061.386-6.902-6.902-6.902
07-6.902-6.902-6.9021.386
08-6.902-6.902-6.9021.386
091.386-6.902-6.902-6.902
100.125-0.8980.88-3.05
11-2.0270.552-0.0240.144
12-0.419-0.1970.586-0.323
13-0.0450.06-0.0460.027
Standard thresholds
P-value Threshold
0.001 2.88136
0.0005 4.986625
0.0001 7.78812