TYY2.H12INVIVO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TYY2.H12INVIVO.1.SM.B
Gene (human)	YY2 (GeneCards)
Gene synonyms (human)	ZNF631
Gene (mouse)	Yy2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	14
Consensus	nhAAAATGGCSGhn
GC content	51.75%
Information content (bits; total / per base)	16.561 / 1.183
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9927

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.846	0.886	0.779	0.836	0.839	0.88	3.836	4.182	130.746	389.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.969	0.959	0.827	0.837	0.676	0.708
Overall, 6 experiments	best	1.0	1.0	1.0	1.0	0.854	0.879
Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.797	0.826	0.639	0.689
Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.797	0.826	0.639	0.689
Non-Methyl HT-SELEX, 5 experiments	median	0.966	0.956	0.858	0.848	0.713	0.728
Non-Methyl HT-SELEX, 5 experiments	best	1.0	1.0	1.0	1.0	0.854	0.879

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	YY1-like {2.3.3.9} (TFClass)
TFClass ID	TFClass: 2.3.3.9.2
HGNC	HGNC:31684
MGI	MGI:3837947
EntrezGene (human)	GeneID:404281 (SSTAR profile)
EntrezGene (mouse)	GeneID:100073351 (SSTAR profile)
UniProt ID (human)	TYY2_HUMAN
UniProt ID (mouse)	TYY2_MOUSE
UniProt AC (human)	O15391 (TFClass)
UniProt AC (mouse)	Q3TTC2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	TYY2.H12INVIVO.1.SM.B.pcm
PWM	TYY2.H12INVIVO.1.SM.B.pwm
PFM	TYY2.H12INVIVO.1.SM.B.pfm
Alignment	TYY2.H12INVIVO.1.SM.B.words.tsv
Threshold to P-value map	TYY2.H12INVIVO.1.SM.B.thr
Motif in other formats
JASPAR format	TYY2.H12INVIVO.1.SM.B_jaspar_format.txt
MEME format	TYY2.H12INVIVO.1.SM.B_meme_format.meme
Transfac format	TYY2.H12INVIVO.1.SM.B_transfac_format.txt
Homer format	TYY2.H12INVIVO.1.SM.B_homer_format_0.001.txt TYY2.H12INVIVO.1.SM.B_homer_format_0.0005.txt TYY2.H12INVIVO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2360.5	2356.5	1504.5	3705.5
02	1366.0	5570.0	1069.0	1922.0
03	9230.0	153.0	380.0	164.0
04	9370.0	105.0	312.0	140.0
05	8673.0	109.0	1081.0	64.0
06	9792.0	10.0	103.0	22.0
07	8.0	7.0	43.0	9869.0
08	24.0	25.0	9872.0	6.0
09	52.0	51.0	9759.0	65.0
10	312.0	9295.0	145.0	175.0
11	262.0	2449.0	6787.0	429.0
12	334.0	265.0	8920.0	408.0
13	2677.75	4745.75	1076.75	1426.75
14	1899.75	3950.75	1770.75	2305.75

PFM

	A	C	G	T
01	0.238	0.237	0.152	0.373
02	0.138	0.561	0.108	0.194
03	0.93	0.015	0.038	0.017
04	0.944	0.011	0.031	0.014
05	0.874	0.011	0.109	0.006
06	0.986	0.001	0.01	0.002
07	0.001	0.001	0.004	0.994
08	0.002	0.003	0.994	0.001
09	0.005	0.005	0.983	0.007
10	0.031	0.936	0.015	0.018
11	0.026	0.247	0.684	0.043
12	0.034	0.027	0.899	0.041
13	0.27	0.478	0.108	0.144
14	0.191	0.398	0.178	0.232

PWM

	A	C	G	T
01	-0.05	-0.052	-0.5	0.401
02	-0.596	0.808	-0.841	-0.255
03	1.313	-2.772	-1.871	-2.704
04	1.328	-3.142	-2.067	-2.86
05	1.251	-3.105	-0.83	-3.623
06	1.372	-5.308	-3.161	-4.627
07	-5.485	-5.588	-4.004	1.38
08	-4.548	-4.511	1.38	-5.701
09	-3.823	-3.842	1.369	-3.608
10	-2.067	1.32	-2.825	-2.64
11	-2.241	-0.013	1.005	-1.751
12	-2.0	-2.229	1.279	-1.801
13	0.076	0.648	-0.834	-0.553
14	-0.267	0.465	-0.337	-0.073

Standard thresholds

P-value	Threshold
0.001	1.45031
0.0005	2.86816
0.0001	5.77051