TYY2.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TYY2.H12INVIVO.0.PS.A
Gene (human)	YY2 (GeneCards)
Gene synonyms (human)	ZNF631
Gene (mouse)	Yy2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	vRMvATGGCSGC
GC content	62.31%
Information content (bits; total / per base)	14.642 / 1.22
Data sources	ChIP-Seq + HT-SELEX
Aligned words	980

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.911	0.958	0.859	0.921	0.891	0.952	4.699	5.227	179.489	553.092

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.979	0.97	0.845	0.852	0.693	0.722
Overall, 6 experiments	best	1.0	0.999	0.998	0.998	0.862	0.883
Methyl HT-SELEX, 1 experiments	median	0.995	0.993	0.804	0.827	0.65	0.693
Methyl HT-SELEX, 1 experiments	best	0.995	0.993	0.804	0.827	0.65	0.693
Non-Methyl HT-SELEX, 5 experiments	median	0.976	0.966	0.887	0.877	0.735	0.75
Non-Methyl HT-SELEX, 5 experiments	best	1.0	0.999	0.998	0.998	0.862	0.883

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	YY1-like {2.3.3.9} (TFClass)
TFClass ID	TFClass: 2.3.3.9.2
HGNC	HGNC:31684
MGI	MGI:3837947
EntrezGene (human)	GeneID:404281 (SSTAR profile)
EntrezGene (mouse)	GeneID:100073351 (SSTAR profile)
UniProt ID (human)	TYY2_HUMAN
UniProt ID (mouse)	TYY2_MOUSE
UniProt AC (human)	O15391 (TFClass)
UniProt AC (mouse)	Q3TTC2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	TYY2.H12INVIVO.0.PS.A.pcm
PWM	TYY2.H12INVIVO.0.PS.A.pwm
PFM	TYY2.H12INVIVO.0.PS.A.pfm
Alignment	TYY2.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	TYY2.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	TYY2.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	TYY2.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	TYY2.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	TYY2.H12INVIVO.0.PS.A_homer_format_0.001.txt TYY2.H12INVIVO.0.PS.A_homer_format_0.0005.txt TYY2.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	168.0	492.0	215.0	105.0
02	724.0	24.0	212.0	20.0
03	643.0	135.0	68.0	134.0
04	234.0	283.0	417.0	46.0
05	977.0	0.0	2.0	1.0
06	2.0	2.0	1.0	975.0
07	0.0	0.0	980.0	0.0
08	3.0	5.0	968.0	4.0
09	21.0	945.0	0.0	14.0
10	51.0	103.0	739.0	87.0
11	41.0	58.0	832.0	49.0
12	84.0	822.0	25.0	49.0

PFM

	A	C	G	T
01	0.171	0.502	0.219	0.107
02	0.739	0.024	0.216	0.02
03	0.656	0.138	0.069	0.137
04	0.239	0.289	0.426	0.047
05	0.997	0.0	0.002	0.001
06	0.002	0.002	0.001	0.995
07	0.0	0.0	1.0	0.0
08	0.003	0.005	0.988	0.004
09	0.021	0.964	0.0	0.014
10	0.052	0.105	0.754	0.089
11	0.042	0.059	0.849	0.05
12	0.086	0.839	0.026	0.05

PWM

	A	C	G	T
01	-0.374	0.694	-0.13	-0.838
02	1.079	-2.261	-0.144	-2.43
03	0.961	-0.59	-1.264	-0.598
04	-0.046	0.143	0.529	-1.643
05	1.378	-4.965	-4.194	-4.507
06	-4.194	-4.194	-4.507	1.376
07	-4.965	-4.965	1.381	-4.965
08	-3.956	-3.603	1.369	-3.764
09	-2.385	1.345	-4.965	-2.753
10	-1.543	-0.857	1.099	-1.023
11	-1.754	-1.419	1.218	-1.582
12	-1.057	1.206	-2.223	-1.582

Standard thresholds

P-value	Threshold
0.001	2.741175
0.0005	4.04219
0.0001	6.69332