TYY2.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TYY2.H12INVITRO.0.PS.A
Gene (human)	YY2 (GeneCards)
Gene synonyms (human)	ZNF631
Gene (mouse)	Yy2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	ndhvATGGCGKn
GC content	55.8%
Information content (bits; total / per base)	12.731 / 1.061
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9902

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.904	0.948	0.841	0.902	0.891	0.945	4.006	4.415	172.165	528.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.986	0.983	0.848	0.856	0.695	0.724
Overall, 6 experiments	best	1.0	1.0	1.0	0.999	0.861	0.883
Methyl HT-SELEX, 1 experiments	median	0.987	0.985	0.803	0.823	0.652	0.692
Methyl HT-SELEX, 1 experiments	best	0.987	0.985	0.803	0.823	0.652	0.692
Non-Methyl HT-SELEX, 5 experiments	median	0.986	0.98	0.893	0.888	0.737	0.756
Non-Methyl HT-SELEX, 5 experiments	best	1.0	1.0	1.0	0.999	0.861	0.883

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	YY1-like {2.3.3.9} (TFClass)
TFClass ID	TFClass: 2.3.3.9.2
HGNC	HGNC:31684
MGI	MGI:3837947
EntrezGene (human)	GeneID:404281 (SSTAR profile)
EntrezGene (mouse)	GeneID:100073351 (SSTAR profile)
UniProt ID (human)	TYY2_HUMAN
UniProt ID (mouse)	TYY2_MOUSE
UniProt AC (human)	O15391 (TFClass)
UniProt AC (mouse)	Q3TTC2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	TYY2.H12INVITRO.0.PS.A.pcm
PWM	TYY2.H12INVITRO.0.PS.A.pwm
PFM	TYY2.H12INVITRO.0.PS.A.pfm
Alignment	TYY2.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	TYY2.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	TYY2.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	TYY2.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	TYY2.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	TYY2.H12INVITRO.0.PS.A_homer_format_0.001.txt TYY2.H12INVITRO.0.PS.A_homer_format_0.0005.txt TYY2.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2741.25	3097.25	1955.25	2108.25
02	5605.5	808.5	2142.5	1345.5
03	4213.0	1451.0	1235.0	3003.0
04	4876.0	1511.0	2175.0	1340.0
05	9808.0	11.0	73.0	10.0
06	2.0	22.0	6.0	9872.0
07	3.0	0.0	9899.0	0.0
08	4.0	13.0	9877.0	8.0
09	204.0	9569.0	31.0	98.0
10	144.0	363.0	8884.0	511.0
11	649.5	386.5	7871.5	994.5
12	2107.5	2883.5	2040.5	2870.5

PFM

	A	C	G	T
01	0.277	0.313	0.197	0.213
02	0.566	0.082	0.216	0.136
03	0.425	0.147	0.125	0.303
04	0.492	0.153	0.22	0.135
05	0.991	0.001	0.007	0.001
06	0.0	0.002	0.001	0.997
07	0.0	0.0	1.0	0.0
08	0.0	0.001	0.997	0.001
09	0.021	0.966	0.003	0.01
10	0.015	0.037	0.897	0.052
11	0.066	0.039	0.795	0.1
12	0.213	0.291	0.206	0.29

PWM

	A	C	G	T
01	0.102	0.224	-0.236	-0.16
02	0.817	-1.117	-0.144	-0.609
03	0.531	-0.534	-0.694	0.193
04	0.677	-0.493	-0.129	-0.613
05	1.376	-5.227	-3.494	-5.306
06	-6.356	-4.625	-5.699	1.383
07	-6.147	-6.982	1.385	-6.982
08	-5.975	-5.087	1.383	-5.483
09	-2.486	1.351	-4.31	-3.207
10	-2.829	-1.914	1.277	-1.574
11	-1.335	-1.852	1.156	-0.911
12	-0.161	0.152	-0.193	0.148

Standard thresholds

P-value	Threshold
0.001	3.163965
0.0005	4.59817
0.0001	7.282895