MotifTYY1.H12INVIVO.1.S.B
Gene (human)YY1
(GeneCards)
Gene synonyms (human)INO80S
Gene (mouse)Yy1
Gene synonyms (mouse)Ucrbp
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusndhRATGGCSb
GC content52.78%
Information content (bits; total / per base)11.609 / 1.055
Data sourcesHT-SELEX
Aligned words7771

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 53 (345) 0.941 0.963 0.872 0.912 0.944 0.961 4.09 4.352 361.886 638.638
Mouse 28 (176) 0.937 0.968 0.867 0.941 0.933 0.963 3.796 4.358 295.328 705.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.933 0.915 0.783 0.778 0.65 0.671
best 0.996 0.995 0.99 0.986 0.892 0.897
Methyl HT-SELEX, 1 experiments median 0.996 0.995 0.99 0.986 0.892 0.897
best 0.996 0.995 0.99 0.986 0.892 0.897
Non-Methyl HT-SELEX, 3 experiments median 0.923 0.9 0.777 0.776 0.644 0.67
best 0.944 0.931 0.789 0.78 0.657 0.673

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.383 2.919 0.164 0.139
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyYY1-like {2.3.3.9} (TFClass)
TFClass IDTFClass: 2.3.3.9.1
HGNCHGNC:12856
MGIMGI:99150
EntrezGene (human)GeneID:7528
(SSTAR profile)
EntrezGene (mouse)GeneID:22632
(SSTAR profile)
UniProt ID (human)TYY1_HUMAN
UniProt ID (mouse)TYY1_MOUSE
UniProt AC (human)P25490
(TFClass)
UniProt AC (mouse)Q00899
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 53 human, 28 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011894.752378.751753.751743.75
023689.5681.52040.51359.5
032964.01275.0483.03049.0
045528.0698.01208.0337.0
057771.00.00.00.0
060.00.00.07771.0
070.00.07771.00.0
080.00.07771.00.0
09377.06964.011.0419.0
10278.01238.05393.0862.0
111010.51252.54196.51311.5
PFM
ACGT
010.2440.3060.2260.224
020.4750.0880.2630.175
030.3810.1640.0620.392
040.7110.090.1550.043
051.00.00.00.0
060.00.00.01.0
070.00.01.00.0
080.00.01.00.0
090.0490.8960.0010.054
100.0360.1590.6940.111
110.130.1610.540.169
PWM
ACGT
01-0.0250.202-0.102-0.108
020.641-1.0450.049-0.356
030.422-0.421-1.3880.45
041.045-1.022-0.474-1.746
051.385-6.767-6.767-6.767
06-6.767-6.767-6.7671.385
07-6.767-6.7671.385-6.767
08-6.767-6.7671.385-6.767
09-1.6351.276-4.99-1.53
10-1.937-0.451.02-0.811
11-0.653-0.4380.77-0.392
Standard thresholds
P-value Threshold
0.001 4.144655
0.0005 5.47774
0.0001 7.618195