TYY1.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TYY1.H12INVITRO.1.S.B
Gene (human)	YY1 (GeneCards)
Gene synonyms (human)	INO80S
Gene (mouse)	Yy1
Gene synonyms (mouse)	Ucrbp
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	ndhRATGGYbb
GC content	52.11%
Information content (bits; total / per base)	9.975 / 0.907
Data sources	HT-SELEX
Aligned words	9199

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	53 (345)	0.934	0.957	0.86	0.899	0.937	0.953	3.864	4.11	343.62	603.523
Mouse	28 (176)	0.93	0.962	0.852	0.924	0.925	0.956	3.566	4.104	285.372	692.328

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.932	0.913	0.783	0.777	0.666	0.677
Overall, 4 experiments	best	0.996	0.995	0.989	0.985	0.894	0.898
Methyl HT-SELEX, 1 experiments	median	0.996	0.995	0.989	0.985	0.894	0.898
Methyl HT-SELEX, 1 experiments	best	0.996	0.995	0.989	0.985	0.894	0.898
Non-Methyl HT-SELEX, 3 experiments	median	0.924	0.901	0.777	0.777	0.658	0.674
Non-Methyl HT-SELEX, 3 experiments	best	0.939	0.924	0.789	0.778	0.673	0.679

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.163	2.337	0.179	0.135

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	YY1-like {2.3.3.9} (TFClass)
TFClass ID	TFClass: 2.3.3.9.1
HGNC	HGNC:12856
MGI	MGI:99150
EntrezGene (human)	GeneID:7528 (SSTAR profile)
EntrezGene (mouse)	GeneID:22632 (SSTAR profile)
UniProt ID (human)	TYY1_HUMAN
UniProt ID (mouse)	TYY1_MOUSE
UniProt AC (human)	P25490 (TFClass)
UniProt AC (mouse)	Q00899 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	53 human, 28 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	TYY1.H12INVITRO.1.S.B.pcm
PWM	TYY1.H12INVITRO.1.S.B.pwm
PFM	TYY1.H12INVITRO.1.S.B.pfm
Alignment	TYY1.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	TYY1.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	TYY1.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	TYY1.H12INVITRO.1.S.B_meme_format.meme
Transfac format	TYY1.H12INVITRO.1.S.B_transfac_format.txt
Homer format	TYY1.H12INVITRO.1.S.B_homer_format_0.001.txt TYY1.H12INVITRO.1.S.B_homer_format_0.0005.txt TYY1.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2231.5	2572.5	2277.5	2117.5
02	3811.75	1061.75	2672.75	1652.75
03	3101.0	1744.0	1026.0	3328.0
04	5982.0	1054.0	1490.0	673.0
05	9031.0	2.0	158.0	8.0
06	1.0	0.0	4.0	9194.0
07	4.0	0.0	9195.0	0.0
08	22.0	3.0	9084.0	90.0
09	899.0	6907.0	335.0	1058.0
10	780.0	1701.0	5376.0	1342.0
11	1463.0	1569.0	4497.0	1670.0

PFM

	A	C	G	T
01	0.243	0.28	0.248	0.23
02	0.414	0.115	0.291	0.18
03	0.337	0.19	0.112	0.362
04	0.65	0.115	0.162	0.073
05	0.982	0.0	0.017	0.001
06	0.0	0.0	0.0	0.999
07	0.0	0.0	1.0	0.0
08	0.002	0.0	0.987	0.01
09	0.098	0.751	0.036	0.115
10	0.085	0.185	0.584	0.146
11	0.159	0.171	0.489	0.182

PWM

	A	C	G	T
01	-0.03	0.112	-0.01	-0.082
02	0.505	-0.772	0.15	-0.33
03	0.299	-0.276	-0.806	0.369
04	0.955	-0.779	-0.433	-1.226
05	1.367	-6.287	-2.665	-5.411
06	-6.553	-6.917	-5.904	1.385
07	-5.904	-6.917	1.385	-6.917
08	-4.552	-6.077	1.373	-3.217
09	-0.938	1.099	-1.921	-0.775
10	-1.079	-0.301	0.849	-0.538
11	-0.452	-0.382	0.67	-0.32

Standard thresholds

P-value	Threshold
0.001	5.055485
0.0005	5.94662
0.0001	7.493055