TYY1.H12CORE.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TYY1.H12CORE.1.S.B
Gene (human)	YY1 (GeneCards)
Gene synonyms (human)	INO80S
Gene (mouse)	Yy1
Gene synonyms (mouse)	Ucrbp
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	ndhRATGGCSb
GC content	52.78%
Information content (bits; total / per base)	11.609 / 1.055
Data sources	HT-SELEX
Aligned words	7771

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	53 (345)	0.941	0.963	0.872	0.912	0.944	0.961	4.09	4.352	361.886	638.638
Mouse	28 (176)	0.937	0.968	0.867	0.941	0.933	0.963	3.796	4.358	295.328	705.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.933	0.915	0.783	0.778	0.65	0.671
Overall, 4 experiments	best	0.996	0.995	0.99	0.986	0.892	0.897
Methyl HT-SELEX, 1 experiments	median	0.996	0.995	0.99	0.986	0.892	0.897
Methyl HT-SELEX, 1 experiments	best	0.996	0.995	0.99	0.986	0.892	0.897
Non-Methyl HT-SELEX, 3 experiments	median	0.923	0.9	0.777	0.776	0.644	0.67
Non-Methyl HT-SELEX, 3 experiments	best	0.944	0.931	0.789	0.78	0.657	0.673

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.383	2.919	0.164	0.139

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	YY1-like {2.3.3.9} (TFClass)
TFClass ID	TFClass: 2.3.3.9.1
HGNC	HGNC:12856
MGI	MGI:99150
EntrezGene (human)	GeneID:7528 (SSTAR profile)
EntrezGene (mouse)	GeneID:22632 (SSTAR profile)
UniProt ID (human)	TYY1_HUMAN
UniProt ID (mouse)	TYY1_MOUSE
UniProt AC (human)	P25490 (TFClass)
UniProt AC (mouse)	Q00899 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	53 human, 28 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	TYY1.H12CORE.1.S.B.pcm
PWM	TYY1.H12CORE.1.S.B.pwm
PFM	TYY1.H12CORE.1.S.B.pfm
Alignment	TYY1.H12CORE.1.S.B.words.tsv
Threshold to P-value map	TYY1.H12CORE.1.S.B.thr
Motif in other formats
JASPAR format	TYY1.H12CORE.1.S.B_jaspar_format.txt
MEME format	TYY1.H12CORE.1.S.B_meme_format.meme
Transfac format	TYY1.H12CORE.1.S.B_transfac_format.txt
Homer format	TYY1.H12CORE.1.S.B_homer_format_0.001.txt TYY1.H12CORE.1.S.B_homer_format_0.0005.txt TYY1.H12CORE.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1894.75	2378.75	1753.75	1743.75
02	3689.5	681.5	2040.5	1359.5
03	2964.0	1275.0	483.0	3049.0
04	5528.0	698.0	1208.0	337.0
05	7771.0	0.0	0.0	0.0
06	0.0	0.0	0.0	7771.0
07	0.0	0.0	7771.0	0.0
08	0.0	0.0	7771.0	0.0
09	377.0	6964.0	11.0	419.0
10	278.0	1238.0	5393.0	862.0
11	1010.5	1252.5	4196.5	1311.5

PFM

	A	C	G	T
01	0.244	0.306	0.226	0.224
02	0.475	0.088	0.263	0.175
03	0.381	0.164	0.062	0.392
04	0.711	0.09	0.155	0.043
05	1.0	0.0	0.0	0.0
06	0.0	0.0	0.0	1.0
07	0.0	0.0	1.0	0.0
08	0.0	0.0	1.0	0.0
09	0.049	0.896	0.001	0.054
10	0.036	0.159	0.694	0.111
11	0.13	0.161	0.54	0.169

PWM

	A	C	G	T
01	-0.025	0.202	-0.102	-0.108
02	0.641	-1.045	0.049	-0.356
03	0.422	-0.421	-1.388	0.45
04	1.045	-1.022	-0.474	-1.746
05	1.385	-6.767	-6.767	-6.767
06	-6.767	-6.767	-6.767	1.385
07	-6.767	-6.767	1.385	-6.767
08	-6.767	-6.767	1.385	-6.767
09	-1.635	1.276	-4.99	-1.53
10	-1.937	-0.45	1.02	-0.811
11	-0.653	-0.438	0.77	-0.392

Standard thresholds

P-value	Threshold
0.001	4.144655
0.0005	5.47774
0.0001	7.618195