TWST2.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TWST2.H12INVITRO.0.P.D
Gene (human)	TWIST2 (GeneCards)
Gene synonyms (human)	BHLHA39, DERMO1
Gene (mouse)	Twist2
Gene synonyms (mouse)	Dermo1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	19
Consensus	SdbvYKbnnnSCAGMTGKb
GC content	56.08%
Information content (bits; total / per base)	13.646 / 0.718
Data sources	ChIP-Seq
Aligned words	995

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	2 (13)	0.949	0.965	0.901	0.925	0.918	0.948	4.158	4.788	326.854	417.046

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TWIST {1.2.3.2} (TFClass)
TFClass ID	TFClass: 1.2.3.2.2
HGNC	HGNC:20670
MGI	MGI:104685
EntrezGene (human)	GeneID:117581 (SSTAR profile)
EntrezGene (mouse)	GeneID:13345 (SSTAR profile)
UniProt ID (human)	TWST2_HUMAN
UniProt ID (mouse)	TWST2_MOUSE
UniProt AC (human)	Q8WVJ9 (TFClass)
UniProt AC (mouse)	Q9D030 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 2 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	TWST2.H12INVITRO.0.P.D.pcm
PWM	TWST2.H12INVITRO.0.P.D.pwm
PFM	TWST2.H12INVITRO.0.P.D.pfm
Alignment	TWST2.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	TWST2.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	TWST2.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	TWST2.H12INVITRO.0.P.D_meme_format.meme
Transfac format	TWST2.H12INVITRO.0.P.D_transfac_format.txt
Homer format	TWST2.H12INVITRO.0.P.D_homer_format_0.001.txt TWST2.H12INVITRO.0.P.D_homer_format_0.0005.txt TWST2.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	126.0	625.0	143.0	101.0
02	550.0	88.0	152.0	205.0
03	152.0	207.0	430.0	206.0
04	382.0	412.0	161.0	40.0
05	99.0	153.0	70.0	673.0
06	70.0	96.0	669.0	160.0
07	129.0	200.0	521.0	145.0
08	176.0	309.0	295.0	215.0
09	278.0	268.0	219.0	230.0
10	333.0	156.0	256.0	250.0
11	198.0	574.0	222.0	1.0
12	4.0	989.0	0.0	2.0
13	975.0	1.0	3.0	16.0
14	1.0	128.0	797.0	69.0
15	602.0	377.0	12.0	4.0
16	8.0	4.0	0.0	983.0
17	0.0	4.0	988.0	3.0
18	23.0	136.0	300.0	536.0
19	92.0	222.0	415.0	266.0

PFM

	A	C	G	T
01	0.127	0.628	0.144	0.102
02	0.553	0.088	0.153	0.206
03	0.153	0.208	0.432	0.207
04	0.384	0.414	0.162	0.04
05	0.099	0.154	0.07	0.676
06	0.07	0.096	0.672	0.161
07	0.13	0.201	0.524	0.146
08	0.177	0.311	0.296	0.216
09	0.279	0.269	0.22	0.231
10	0.335	0.157	0.257	0.251
11	0.199	0.577	0.223	0.001
12	0.004	0.994	0.0	0.002
13	0.98	0.001	0.003	0.016
14	0.001	0.129	0.801	0.069
15	0.605	0.379	0.012	0.004
16	0.008	0.004	0.0	0.988
17	0.0	0.004	0.993	0.003
18	0.023	0.137	0.302	0.539
19	0.092	0.223	0.417	0.267

PWM

	A	C	G	T
01	-0.673	0.917	-0.549	-0.891
02	0.79	-1.027	-0.488	-0.192
03	-0.488	-0.182	0.544	-0.187
04	0.427	0.502	-0.431	-1.792
05	-0.911	-0.482	-1.251	0.991
06	-1.251	-0.941	0.985	-0.437
07	-0.65	-0.216	0.736	-0.535
08	-0.343	0.216	0.169	-0.145
09	0.11	0.074	-0.126	-0.078
10	0.29	-0.463	0.029	0.005
11	-0.226	0.832	-0.113	-4.521
12	-3.778	1.375	-4.978	-4.208
13	1.361	-4.521	-3.97	-2.648
14	-4.521	-0.658	1.16	-1.265
15	0.88	0.413	-2.904	-3.778
16	-3.249	-3.778	-4.978	1.369
17	-4.978	-3.778	1.374	-3.97
18	-2.316	-0.598	0.186	0.764
19	-0.983	-0.113	0.509	0.067

Standard thresholds

P-value	Threshold
0.001	3.34151
0.0005	4.56711
0.0001	7.04406