TWST1.H12RSNP.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TWST1.H12RSNP.1.P.D
Gene (human)	TWIST1 (GeneCards)
Gene synonyms (human)	BHLHA38, TWIST
Gene (mouse)	Twist1
Gene synonyms (mouse)	Twist
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	16
Consensus	nnnnvCAKMTGKWhhb
GC content	46.57%
Information content (bits; total / per base)	11.393 / 0.712
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (31)	0.87	0.921	0.786	0.851	0.853	0.914	3.273	3.66	390.959	599.215

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TWIST {1.2.3.2} (TFClass)
TFClass ID	TFClass: 1.2.3.2.1
HGNC	HGNC:12428
MGI	MGI:98872
EntrezGene (human)	GeneID:7291 (SSTAR profile)
EntrezGene (mouse)	GeneID:22160 (SSTAR profile)
UniProt ID (human)	TWST1_HUMAN
UniProt ID (mouse)	TWST1_MOUSE
UniProt AC (human)	Q15672 (TFClass)
UniProt AC (mouse)	P26687 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	TWST1.H12RSNP.1.P.D.pcm
PWM	TWST1.H12RSNP.1.P.D.pwm
PFM	TWST1.H12RSNP.1.P.D.pfm
Alignment	TWST1.H12RSNP.1.P.D.words.tsv
Threshold to P-value map	TWST1.H12RSNP.1.P.D.thr
Motif in other formats
JASPAR format	TWST1.H12RSNP.1.P.D_jaspar_format.txt
MEME format	TWST1.H12RSNP.1.P.D_meme_format.meme
Transfac format	TWST1.H12RSNP.1.P.D_transfac_format.txt
Homer format	TWST1.H12RSNP.1.P.D_homer_format_0.001.txt TWST1.H12RSNP.1.P.D_homer_format_0.0005.txt TWST1.H12RSNP.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	242.0	229.0	271.0	258.0
02	231.0	275.0	266.0	228.0
03	255.0	305.0	224.0	216.0
04	333.0	265.0	263.0	139.0
05	479.0	275.0	180.0	66.0
06	49.0	946.0	2.0	3.0
07	966.0	6.0	7.0	21.0
08	17.0	45.0	192.0	746.0
09	178.0	707.0	107.0	8.0
10	5.0	3.0	0.0	992.0
11	1.0	1.0	986.0	12.0
12	17.0	130.0	559.0	294.0
13	281.0	75.0	58.0	586.0
14	288.0	104.0	79.0	529.0
15	100.0	343.0	90.0	467.0
16	63.0	351.0	107.0	479.0

PFM

	A	C	G	T
01	0.242	0.229	0.271	0.258
02	0.231	0.275	0.266	0.228
03	0.255	0.305	0.224	0.216
04	0.333	0.265	0.263	0.139
05	0.479	0.275	0.18	0.066
06	0.049	0.946	0.002	0.003
07	0.966	0.006	0.007	0.021
08	0.017	0.045	0.192	0.746
09	0.178	0.707	0.107	0.008
10	0.005	0.003	0.0	0.992
11	0.001	0.001	0.986	0.012
12	0.017	0.13	0.559	0.294
13	0.281	0.075	0.058	0.586
14	0.288	0.104	0.079	0.529
15	0.1	0.343	0.09	0.467
16	0.063	0.351	0.107	0.479

PWM

	A	C	G	T
01	-0.032	-0.087	0.08	0.031
02	-0.078	0.095	0.062	-0.091
03	0.02	0.198	-0.109	-0.145
04	0.285	0.058	0.05	-0.582
05	0.647	0.095	-0.326	-1.313
06	-1.602	1.326	-4.213	-3.975
07	1.347	-3.484	-3.362	-2.405
08	-2.598	-1.684	-0.262	1.089
09	-0.337	1.035	-0.84	-3.253
10	-3.622	-3.975	-4.982	1.373
11	-4.525	-4.525	1.367	-2.909
12	-2.598	-0.648	0.801	0.161
13	0.116	-1.188	-1.439	0.848
14	0.141	-0.867	-1.137	0.746
15	-0.906	0.314	-1.01	0.622
16	-1.358	0.337	-0.84	0.647

Standard thresholds

P-value	Threshold
0.001	4.34026
0.0005	5.37421
0.0001	7.39321