MotifTWST1.H12INVIVO.1.P.B
Gene (human)TWIST1
(GeneCards)
Gene synonyms (human)BHLHA38, TWIST
Gene (mouse)Twist1
Gene synonyms (mouse)Twist
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length16
ConsensusnnnnvCAKMTGKWhhb
GC content46.57%
Information content (bits; total / per base)11.393 / 0.712
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (31) 0.87 0.921 0.786 0.851 0.853 0.914 3.273 3.66 390.959 599.215
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyTWIST {1.2.3.2} (TFClass)
TFClass IDTFClass: 1.2.3.2.1
HGNCHGNC:12428
MGIMGI:98872
EntrezGene (human)GeneID:7291
(SSTAR profile)
EntrezGene (mouse)GeneID:22160
(SSTAR profile)
UniProt ID (human)TWST1_HUMAN
UniProt ID (mouse)TWST1_MOUSE
UniProt AC (human)Q15672
(TFClass)
UniProt AC (mouse)P26687
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 0 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01242.0229.0271.0258.0
02231.0275.0266.0228.0
03255.0305.0224.0216.0
04333.0265.0263.0139.0
05479.0275.0180.066.0
0649.0946.02.03.0
07966.06.07.021.0
0817.045.0192.0746.0
09178.0707.0107.08.0
105.03.00.0992.0
111.01.0986.012.0
1217.0130.0559.0294.0
13281.075.058.0586.0
14288.0104.079.0529.0
15100.0343.090.0467.0
1663.0351.0107.0479.0
PFM
ACGT
010.2420.2290.2710.258
020.2310.2750.2660.228
030.2550.3050.2240.216
040.3330.2650.2630.139
050.4790.2750.180.066
060.0490.9460.0020.003
070.9660.0060.0070.021
080.0170.0450.1920.746
090.1780.7070.1070.008
100.0050.0030.00.992
110.0010.0010.9860.012
120.0170.130.5590.294
130.2810.0750.0580.586
140.2880.1040.0790.529
150.10.3430.090.467
160.0630.3510.1070.479
PWM
ACGT
01-0.032-0.0870.080.031
02-0.0780.0950.062-0.091
030.020.198-0.109-0.145
040.2850.0580.05-0.582
050.6470.095-0.326-1.313
06-1.6021.326-4.213-3.975
071.347-3.484-3.362-2.405
08-2.598-1.684-0.2621.089
09-0.3371.035-0.84-3.253
10-3.622-3.975-4.9821.373
11-4.525-4.5251.367-2.909
12-2.598-0.6480.8010.161
130.116-1.188-1.4390.848
140.141-0.867-1.1370.746
15-0.9060.314-1.010.622
16-1.3580.337-0.840.647
Standard thresholds
P-value Threshold
0.001 4.34026
0.0005 5.37421
0.0001 7.39321