TWST1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TWST1.H12CORE.0.P.B
Gene (human)	TWIST1 (GeneCards)
Gene synonyms (human)	BHLHA38, TWIST
Gene (mouse)	Twist1
Gene synonyms (mouse)	Twist
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	vCATCTGKhWbbvATYWd
GC content	38.6%
Information content (bits; total / per base)	16.773 / 0.932
Data sources	ChIP-Seq
Aligned words	704

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (31)	0.917	0.961	0.892	0.946	0.916	0.965	5.428	6.056	478.31	717.62

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TWIST {1.2.3.2} (TFClass)
TFClass ID	TFClass: 1.2.3.2.1
HGNC	HGNC:12428
MGI	MGI:98872
EntrezGene (human)	GeneID:7291 (SSTAR profile)
EntrezGene (mouse)	GeneID:22160 (SSTAR profile)
UniProt ID (human)	TWST1_HUMAN
UniProt ID (mouse)	TWST1_MOUSE
UniProt AC (human)	Q15672 (TFClass)
UniProt AC (mouse)	P26687 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	TWST1.H12CORE.0.P.B.pcm
PWM	TWST1.H12CORE.0.P.B.pwm
PFM	TWST1.H12CORE.0.P.B.pfm
Alignment	TWST1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	TWST1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	TWST1.H12CORE.0.P.B_jaspar_format.txt
MEME format	TWST1.H12CORE.0.P.B_meme_format.meme
Transfac format	TWST1.H12CORE.0.P.B_transfac_format.txt
Homer format	TWST1.H12CORE.0.P.B_homer_format_0.001.txt TWST1.H12CORE.0.P.B_homer_format_0.0005.txt TWST1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	383.0	150.0	140.0	31.0
02	26.0	670.0	7.0	1.0
03	684.0	3.0	8.0	9.0
04	3.0	27.0	134.0	540.0
05	83.0	569.0	48.0	4.0
06	2.0	0.0	0.0	702.0
07	1.0	1.0	697.0	5.0
08	9.0	79.0	418.0	198.0
09	205.0	81.0	45.0	373.0
10	173.0	61.0	60.0	410.0
11	61.0	221.0	81.0	341.0
12	47.0	266.0	74.0	317.0
13	303.0	265.0	83.0	53.0
14	620.0	26.0	40.0	18.0
15	0.0	22.0	36.0	646.0
16	58.0	91.0	33.0	522.0
17	456.0	17.0	28.0	203.0
18	173.0	80.0	331.0	120.0

PFM

	A	C	G	T
01	0.544	0.213	0.199	0.044
02	0.037	0.952	0.01	0.001
03	0.972	0.004	0.011	0.013
04	0.004	0.038	0.19	0.767
05	0.118	0.808	0.068	0.006
06	0.003	0.0	0.0	0.997
07	0.001	0.001	0.99	0.007
08	0.013	0.112	0.594	0.281
09	0.291	0.115	0.064	0.53
10	0.246	0.087	0.085	0.582
11	0.087	0.314	0.115	0.484
12	0.067	0.378	0.105	0.45
13	0.43	0.376	0.118	0.075
14	0.881	0.037	0.057	0.026
15	0.0	0.031	0.051	0.918
16	0.082	0.129	0.047	0.741
17	0.648	0.024	0.04	0.288
18	0.246	0.114	0.47	0.17

PWM

	A	C	G	T
01	0.773	-0.158	-0.226	-1.694
02	-1.861	1.33	-3.023	-4.209
03	1.351	-3.645	-2.914	-2.815
04	-3.645	-1.825	-0.27	1.115
05	-0.741	1.167	-1.275	-3.45
06	-3.888	-4.686	-4.686	1.377
07	-4.209	-4.209	1.369	-3.287
08	-2.815	-0.79	0.86	0.117
09	0.151	-0.765	-1.337	0.746
10	-0.017	-1.042	-1.058	0.84
11	-1.042	0.226	-0.765	0.657
12	-1.295	0.41	-0.854	0.584
13	0.539	0.406	-0.741	-1.179
14	1.253	-1.861	-1.451	-2.202
15	-4.686	-2.017	-1.552	1.294
16	-1.091	-0.651	-1.635	1.081
17	0.946	-2.254	-1.791	0.141
18	-0.017	-0.777	0.627	-0.379

Standard thresholds

P-value	Threshold
0.001	2.20051
0.0005	3.46506
0.0001	6.10676