Motif | TLX3.H12CORE.0.SM.B |
Gene (human) | TLX3 (GeneCards) |
Gene synonyms (human) | HOX11L2 |
Gene (mouse) | Tlx3 |
Gene synonyms (mouse) | Hox11l2, Rnx, Tlx1l2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | TLX3.H12CORE.0.SM.B |
Gene (human) | TLX3 (GeneCards) |
Gene synonyms (human) | HOX11L2 |
Gene (mouse) | Tlx3 |
Gene synonyms (mouse) | Hox11l2, Rnx, Tlx1l2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 12 |
Consensus | nhSTTAAYKRnn |
GC content | 35.32% |
Information content (bits; total / per base) | 9.872 / 0.823 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 2244 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 3 experiments | median | 0.724 | 0.669 | 0.662 | 0.62 | 0.607 | 0.585 |
best | 0.785 | 0.724 | 0.72 | 0.671 | 0.652 | 0.625 | |
Methyl HT-SELEX, 2 experiments | median | 0.755 | 0.697 | 0.687 | 0.645 | 0.624 | 0.603 |
best | 0.785 | 0.724 | 0.72 | 0.671 | 0.652 | 0.625 | |
Non-Methyl HT-SELEX, 1 experiments | median | 0.717 | 0.659 | 0.662 | 0.619 | 0.607 | 0.585 |
best | 0.717 | 0.659 | 0.662 | 0.619 | 0.607 | 0.585 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.592 | 0.127 | 0.514 | 0.302 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | TLX {3.1.2.21} (TFClass) |
TFClass ID | TFClass: 3.1.2.21.3 |
HGNC | HGNC:13532 |
MGI | MGI:1351209 |
EntrezGene (human) | GeneID:30012 (SSTAR profile) |
EntrezGene (mouse) | GeneID:27140 (SSTAR profile) |
UniProt ID (human) | TLX3_HUMAN |
UniProt ID (mouse) | TLX3_MOUSE |
UniProt AC (human) | O43711 (TFClass) |
UniProt AC (mouse) | O55144 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 2 |
PCM | TLX3.H12CORE.0.SM.B.pcm |
PWM | TLX3.H12CORE.0.SM.B.pwm |
PFM | TLX3.H12CORE.0.SM.B.pfm |
Alignment | TLX3.H12CORE.0.SM.B.words.tsv |
Threshold to P-value map | TLX3.H12CORE.0.SM.B.thr |
Motif in other formats | |
JASPAR format | TLX3.H12CORE.0.SM.B_jaspar_format.txt |
MEME format | TLX3.H12CORE.0.SM.B_meme_format.meme |
Transfac format | TLX3.H12CORE.0.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 762.25 | 351.25 | 504.25 | 626.25 |
02 | 417.75 | 1152.75 | 291.75 | 381.75 |
03 | 421.0 | 450.0 | 1278.0 | 95.0 |
04 | 22.0 | 176.0 | 41.0 | 2005.0 |
05 | 0.0 | 12.0 | 0.0 | 2232.0 |
06 | 2243.0 | 0.0 | 1.0 | 0.0 |
07 | 2244.0 | 0.0 | 0.0 | 0.0 |
08 | 195.0 | 391.0 | 195.0 | 1463.0 |
09 | 144.0 | 195.0 | 743.0 | 1162.0 |
10 | 1025.0 | 36.0 | 1146.0 | 37.0 |
11 | 549.75 | 635.75 | 696.75 | 361.75 |
12 | 444.0 | 624.0 | 591.0 | 585.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.34 | 0.157 | 0.225 | 0.279 |
02 | 0.186 | 0.514 | 0.13 | 0.17 |
03 | 0.188 | 0.201 | 0.57 | 0.042 |
04 | 0.01 | 0.078 | 0.018 | 0.893 |
05 | 0.0 | 0.005 | 0.0 | 0.995 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.087 | 0.174 | 0.087 | 0.652 |
09 | 0.064 | 0.087 | 0.331 | 0.518 |
10 | 0.457 | 0.016 | 0.511 | 0.016 |
11 | 0.245 | 0.283 | 0.31 | 0.161 |
12 | 0.198 | 0.278 | 0.263 | 0.261 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.306 | -0.466 | -0.106 | 0.11 |
02 | -0.294 | 0.718 | -0.651 | -0.383 |
03 | -0.286 | -0.22 | 0.821 | -1.759 |
04 | -3.158 | -1.152 | -2.574 | 1.271 |
05 | -5.676 | -3.699 | -5.676 | 1.378 |
06 | 1.383 | -5.676 | -5.258 | -5.676 |
07 | 1.384 | -5.676 | -5.676 | -5.676 |
08 | -1.05 | -0.36 | -1.05 | 0.956 |
09 | -1.35 | -1.05 | 0.28 | 0.726 |
10 | 0.601 | -2.697 | 0.713 | -2.671 |
11 | -0.02 | 0.125 | 0.216 | -0.437 |
12 | -0.233 | 0.106 | 0.052 | 0.042 |
P-value | Threshold |
---|---|
0.001 | 5.02587 |
0.0005 | 5.94969 |
0.0001 | 7.50333 |