MotifTLX2.H12CORE.0.SM.B
Gene (human)TLX2
(GeneCards)
Gene synonyms (human)HOX11L1, NCX
Gene (mouse)Tlx2
Gene synonyms (mouse)Enx, Hox11l1, Ncx, Tlx1l1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnbYAATTARbbn
GC content35.98%
Information content (bits; total / per base)10.862 / 0.905
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8661

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.964 0.938 0.949 0.918 0.925 0.89
best 0.964 0.94 0.949 0.918 0.927 0.892
Methyl HT-SELEX, 1 experiments median 0.963 0.936 0.949 0.918 0.927 0.892
best 0.963 0.936 0.949 0.918 0.927 0.892
Non-Methyl HT-SELEX, 1 experiments median 0.964 0.94 0.948 0.918 0.924 0.889
best 0.964 0.94 0.948 0.918 0.924 0.889

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.624 0.088 0.486 0.222
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyTLX {3.1.2.21} (TFClass)
TFClass IDTFClass: 3.1.2.21.2
HGNCHGNC:5057
MGIMGI:1350935
EntrezGene (human)GeneID:3196
(SSTAR profile)
EntrezGene (mouse)GeneID:21909
(SSTAR profile)
UniProt ID (human)TLX2_HUMAN
UniProt ID (mouse)TLX2_MOUSE
UniProt AC (human)O43763
(TFClass)
UniProt AC (mouse)Q61663
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012139.02089.02449.01984.0
02770.252512.252964.252414.25
03304.02923.0618.04816.0
046696.0418.01528.019.0
058661.00.00.00.0
060.00.00.08661.0
070.00.00.08661.0
088661.00.00.00.0
091920.0671.06054.016.0
10655.03248.02671.02087.0
111047.01946.03093.02575.0
121958.02277.01929.02497.0
PFM
ACGT
010.2470.2410.2830.229
020.0890.290.3420.279
030.0350.3370.0710.556
040.7730.0480.1760.002
051.00.00.00.0
060.00.00.01.0
070.00.00.01.0
081.00.00.00.0
090.2220.0770.6990.002
100.0760.3750.3080.241
110.1210.2250.3570.297
120.2260.2630.2230.288
PWM
ACGT
01-0.012-0.0360.123-0.087
02-1.0320.1480.3140.109
03-1.9570.3-1.2510.799
041.128-1.64-0.348-4.624
051.386-6.863-6.863-6.863
06-6.863-6.863-6.8631.386
07-6.863-6.863-6.8631.386
081.386-6.863-6.863-6.863
09-0.12-1.1691.028-4.776
10-1.1930.4050.21-0.037
11-0.725-0.1070.3560.173
12-0.1010.05-0.1150.142
Standard thresholds
P-value Threshold
0.001 4.56143
0.0005 5.897195
0.0001 7.727765