Motif | TLX2.H12CORE.0.SM.B |
Gene (human) | TLX2 (GeneCards) |
Gene synonyms (human) | HOX11L1, NCX |
Gene (mouse) | Tlx2 |
Gene synonyms (mouse) | Enx, Hox11l1, Ncx, Tlx1l1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | TLX2.H12CORE.0.SM.B |
Gene (human) | TLX2 (GeneCards) |
Gene synonyms (human) | HOX11L1, NCX |
Gene (mouse) | Tlx2 |
Gene synonyms (mouse) | Enx, Hox11l1, Ncx, Tlx1l1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 12 |
Consensus | nbYAATTARbbn |
GC content | 35.98% |
Information content (bits; total / per base) | 10.862 / 0.905 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 8661 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 0.964 | 0.938 | 0.949 | 0.918 | 0.925 | 0.89 |
best | 0.964 | 0.94 | 0.949 | 0.918 | 0.927 | 0.892 | |
Methyl HT-SELEX, 1 experiments | median | 0.963 | 0.936 | 0.949 | 0.918 | 0.927 | 0.892 |
best | 0.963 | 0.936 | 0.949 | 0.918 | 0.927 | 0.892 | |
Non-Methyl HT-SELEX, 1 experiments | median | 0.964 | 0.94 | 0.948 | 0.918 | 0.924 | 0.889 |
best | 0.964 | 0.94 | 0.948 | 0.918 | 0.924 | 0.889 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.624 | 0.088 | 0.486 | 0.222 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | TLX {3.1.2.21} (TFClass) |
TFClass ID | TFClass: 3.1.2.21.2 |
HGNC | HGNC:5057 |
MGI | MGI:1350935 |
EntrezGene (human) | GeneID:3196 (SSTAR profile) |
EntrezGene (mouse) | GeneID:21909 (SSTAR profile) |
UniProt ID (human) | TLX2_HUMAN |
UniProt ID (mouse) | TLX2_MOUSE |
UniProt AC (human) | O43763 (TFClass) |
UniProt AC (mouse) | Q61663 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | TLX2.H12CORE.0.SM.B.pcm |
PWM | TLX2.H12CORE.0.SM.B.pwm |
PFM | TLX2.H12CORE.0.SM.B.pfm |
Alignment | TLX2.H12CORE.0.SM.B.words.tsv |
Threshold to P-value map | TLX2.H12CORE.0.SM.B.thr |
Motif in other formats | |
JASPAR format | TLX2.H12CORE.0.SM.B_jaspar_format.txt |
MEME format | TLX2.H12CORE.0.SM.B_meme_format.meme |
Transfac format | TLX2.H12CORE.0.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2139.0 | 2089.0 | 2449.0 | 1984.0 |
02 | 770.25 | 2512.25 | 2964.25 | 2414.25 |
03 | 304.0 | 2923.0 | 618.0 | 4816.0 |
04 | 6696.0 | 418.0 | 1528.0 | 19.0 |
05 | 8661.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 0.0 | 0.0 | 8661.0 |
07 | 0.0 | 0.0 | 0.0 | 8661.0 |
08 | 8661.0 | 0.0 | 0.0 | 0.0 |
09 | 1920.0 | 671.0 | 6054.0 | 16.0 |
10 | 655.0 | 3248.0 | 2671.0 | 2087.0 |
11 | 1047.0 | 1946.0 | 3093.0 | 2575.0 |
12 | 1958.0 | 2277.0 | 1929.0 | 2497.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.247 | 0.241 | 0.283 | 0.229 |
02 | 0.089 | 0.29 | 0.342 | 0.279 |
03 | 0.035 | 0.337 | 0.071 | 0.556 |
04 | 0.773 | 0.048 | 0.176 | 0.002 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 0.0 | 0.0 | 0.0 | 1.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 1.0 | 0.0 | 0.0 | 0.0 |
09 | 0.222 | 0.077 | 0.699 | 0.002 |
10 | 0.076 | 0.375 | 0.308 | 0.241 |
11 | 0.121 | 0.225 | 0.357 | 0.297 |
12 | 0.226 | 0.263 | 0.223 | 0.288 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.012 | -0.036 | 0.123 | -0.087 |
02 | -1.032 | 0.148 | 0.314 | 0.109 |
03 | -1.957 | 0.3 | -1.251 | 0.799 |
04 | 1.128 | -1.64 | -0.348 | -4.624 |
05 | 1.386 | -6.863 | -6.863 | -6.863 |
06 | -6.863 | -6.863 | -6.863 | 1.386 |
07 | -6.863 | -6.863 | -6.863 | 1.386 |
08 | 1.386 | -6.863 | -6.863 | -6.863 |
09 | -0.12 | -1.169 | 1.028 | -4.776 |
10 | -1.193 | 0.405 | 0.21 | -0.037 |
11 | -0.725 | -0.107 | 0.356 | 0.173 |
12 | -0.101 | 0.05 | -0.115 | 0.142 |
P-value | Threshold |
---|---|
0.001 | 4.56143 |
0.0005 | 5.897195 |
0.0001 | 7.727765 |