MotifTHB.H12INVIVO.3.S.C
Gene (human)THRB
(GeneCards)
Gene synonyms (human)ERBA2, NR1A2, THR1
Gene (mouse)Thrb
Gene synonyms (mouse)Erba2, Nr1a2
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
C
Motif length22
ConsensusndbddvMYYdnRTRAGGTCAhn
GC content45.4%
Information content (bits; total / per base)18.675 / 0.849
Data sourcesHT-SELEX
Aligned words682

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.686 0.704 0.498 0.512 0.687 0.693 1.903 1.961 63.092 77.244
Mouse 1 (5) 0.558 0.563 0.414 0.426 0.547 0.569 1.231 1.328 11.886 17.347

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.943 0.91 0.911 0.871 0.845 0.809
best 0.998 0.997 0.994 0.992 0.974 0.968
Methyl HT-SELEX, 2 experiments median 0.972 0.956 0.954 0.933 0.912 0.891
best 0.998 0.997 0.994 0.992 0.974 0.968
Non-Methyl HT-SELEX, 4 experiments median 0.834 0.82 0.761 0.747 0.697 0.689
best 0.997 0.996 0.992 0.989 0.967 0.96
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyT3R (NR1A) {2.1.2.2} (TFClass)
TFClass IDTFClass: 2.1.2.2.2
HGNCHGNC:11799
MGIMGI:98743
EntrezGene (human)GeneID:7068
(SSTAR profile)
EntrezGene (mouse)GeneID:21834
(SSTAR profile)
UniProt ID (human)THB_HUMAN
UniProt ID (mouse)THB_MOUSE
UniProt AC (human)P10828
(TFClass)
UniProt AC (mouse)P37242
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01205.25171.25122.25183.25
02114.590.5250.5226.5
0391.0116.0155.0320.0
04120.081.0223.0258.0
05225.028.0196.0233.0
06208.0184.0264.026.0
07227.0368.050.037.0
087.0453.08.0214.0
0951.0336.018.0277.0
10192.061.080.0349.0
11218.0224.0113.0127.0
12398.071.0166.047.0
134.07.01.0670.0
14489.011.0171.011.0
15682.00.00.00.0
160.01.0681.00.0
170.00.0682.00.0
180.00.00.0682.0
191.0680.01.00.0
20672.01.09.00.0
21114.5267.557.5242.5
2298.5181.5231.5170.5
PFM
ACGT
010.3010.2510.1790.269
020.1680.1330.3670.332
030.1330.170.2270.469
040.1760.1190.3270.378
050.330.0410.2870.342
060.3050.270.3870.038
070.3330.540.0730.054
080.010.6640.0120.314
090.0750.4930.0260.406
100.2820.0890.1170.512
110.320.3280.1660.186
120.5840.1040.2430.069
130.0060.010.0010.982
140.7170.0160.2510.016
151.00.00.00.0
160.00.0010.9990.0
170.00.01.00.0
180.00.00.01.0
190.0010.9970.0010.0
200.9850.0010.0130.0
210.1680.3920.0840.356
220.1440.2660.3390.25
PWM
ACGT
010.1840.004-0.3290.071
02-0.394-0.6250.3820.282
03-0.62-0.381-0.0940.625
04-0.347-0.7340.2660.411
050.275-1.7590.1380.31
060.1970.0760.434-1.829
070.2840.764-1.204-1.494
08-2.9930.971-2.8830.225
09-1.1850.674-2.1710.482
100.118-1.011-0.7460.711
110.2440.271-0.407-0.291
120.842-0.863-0.026-1.264
13-3.42-2.993-4.1811.361
141.047-2.6120.003-2.612
151.379-4.659-4.659-4.659
16-4.659-4.1811.378-4.659
17-4.659-4.6591.379-4.659
18-4.659-4.659-4.6591.379
19-4.1811.376-4.181-4.659
201.364-4.181-2.784-4.659
21-0.3940.447-1.0680.349
22-0.5420.0620.3030.0
Standard thresholds
P-value Threshold
0.001 -0.19694
0.0005 1.38221
0.0001 4.77196