Motif | THB.H12CORE.0.P.B |
Gene (human) | THRB (GeneCards) |
Gene synonyms (human) | ERBA2, NR1A2, THR1 |
Gene (mouse) | Thrb |
Gene synonyms (mouse) | Erba2, Nr1a2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | THB.H12CORE.0.P.B |
Gene (human) | THRB (GeneCards) |
Gene synonyms (human) | ERBA2, NR1A2, THR1 |
Gene (mouse) | Thrb |
Gene synonyms (mouse) | Erba2, Nr1a2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 17 |
Consensus | vRGKKYRnnYvAGGhSA |
GC content | 55.82% |
Information content (bits; total / per base) | 13.038 / 0.767 |
Data sources | ChIP-Seq |
Aligned words | 1000 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (7) | 0.882 | 0.888 | 0.762 | 0.773 | 0.907 | 0.914 | 4.323 | 4.414 | 301.77 | 343.051 |
Mouse | 1 (5) | 0.709 | 0.763 | 0.661 | 0.744 | 0.675 | 0.742 | 2.62 | 3.156 | 79.215 | 120.509 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 6 experiments | median | 0.861 | 0.818 | 0.79 | 0.746 | 0.714 | 0.684 |
best | 0.958 | 0.945 | 0.897 | 0.871 | 0.838 | 0.802 | |
Methyl HT-SELEX, 2 experiments | median | 0.921 | 0.895 | 0.855 | 0.821 | 0.783 | 0.752 |
best | 0.958 | 0.945 | 0.897 | 0.871 | 0.83 | 0.8 | |
Non-Methyl HT-SELEX, 4 experiments | median | 0.715 | 0.678 | 0.659 | 0.631 | 0.61 | 0.594 |
best | 0.947 | 0.927 | 0.896 | 0.864 | 0.838 | 0.802 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
TF family | Thyroid hormone receptor-related {2.1.2} (TFClass) |
TF subfamily | T3R (NR1A) {2.1.2.2} (TFClass) |
TFClass ID | TFClass: 2.1.2.2.2 |
HGNC | HGNC:11799 |
MGI | MGI:98743 |
EntrezGene (human) | GeneID:7068 (SSTAR profile) |
EntrezGene (mouse) | GeneID:21834 (SSTAR profile) |
UniProt ID (human) | THB_HUMAN |
UniProt ID (mouse) | THB_MOUSE |
UniProt AC (human) | P10828 (TFClass) |
UniProt AC (mouse) | P37242 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 1 mouse |
HT-SELEX | 4 |
Methyl-HT-SELEX | 2 |
PCM | THB.H12CORE.0.P.B.pcm |
PWM | THB.H12CORE.0.P.B.pwm |
PFM | THB.H12CORE.0.P.B.pfm |
Alignment | THB.H12CORE.0.P.B.words.tsv |
Threshold to P-value map | THB.H12CORE.0.P.B.thr |
Motif in other formats | |
JASPAR format | THB.H12CORE.0.P.B_jaspar_format.txt |
MEME format | THB.H12CORE.0.P.B_meme_format.meme |
Transfac format | THB.H12CORE.0.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 295.0 | 150.0 | 436.0 | 119.0 |
02 | 521.0 | 15.0 | 450.0 | 14.0 |
03 | 68.0 | 12.0 | 859.0 | 61.0 |
04 | 117.0 | 10.0 | 729.0 | 144.0 |
05 | 16.0 | 122.0 | 170.0 | 692.0 |
06 | 49.0 | 704.0 | 119.0 | 128.0 |
07 | 796.0 | 43.0 | 102.0 | 59.0 |
08 | 162.0 | 310.0 | 227.0 | 301.0 |
09 | 175.0 | 384.0 | 181.0 | 260.0 |
10 | 33.0 | 298.0 | 84.0 | 585.0 |
11 | 242.0 | 209.0 | 490.0 | 59.0 |
12 | 763.0 | 11.0 | 216.0 | 10.0 |
13 | 5.0 | 1.0 | 976.0 | 18.0 |
14 | 4.0 | 6.0 | 934.0 | 56.0 |
15 | 283.0 | 175.0 | 85.0 | 457.0 |
16 | 66.0 | 765.0 | 95.0 | 74.0 |
17 | 823.0 | 44.0 | 77.0 | 56.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.295 | 0.15 | 0.436 | 0.119 |
02 | 0.521 | 0.015 | 0.45 | 0.014 |
03 | 0.068 | 0.012 | 0.859 | 0.061 |
04 | 0.117 | 0.01 | 0.729 | 0.144 |
05 | 0.016 | 0.122 | 0.17 | 0.692 |
06 | 0.049 | 0.704 | 0.119 | 0.128 |
07 | 0.796 | 0.043 | 0.102 | 0.059 |
08 | 0.162 | 0.31 | 0.227 | 0.301 |
09 | 0.175 | 0.384 | 0.181 | 0.26 |
10 | 0.033 | 0.298 | 0.084 | 0.585 |
11 | 0.242 | 0.209 | 0.49 | 0.059 |
12 | 0.763 | 0.011 | 0.216 | 0.01 |
13 | 0.005 | 0.001 | 0.976 | 0.018 |
14 | 0.004 | 0.006 | 0.934 | 0.056 |
15 | 0.283 | 0.175 | 0.085 | 0.457 |
16 | 0.066 | 0.765 | 0.095 | 0.074 |
17 | 0.823 | 0.044 | 0.077 | 0.056 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.164 | -0.506 | 0.553 | -0.735 |
02 | 0.731 | -2.711 | 0.585 | -2.773 |
03 | -1.284 | -2.909 | 1.229 | -1.39 |
04 | -0.752 | -3.066 | 1.066 | -0.547 |
05 | -2.653 | -0.71 | -0.382 | 1.014 |
06 | -1.602 | 1.031 | -0.735 | -0.663 |
07 | 1.153 | -1.728 | -0.887 | -1.422 |
08 | -0.43 | 0.214 | -0.096 | 0.184 |
09 | -0.354 | 0.427 | -0.32 | 0.039 |
10 | -1.981 | 0.175 | -1.077 | 0.846 |
11 | -0.032 | -0.178 | 0.67 | -1.422 |
12 | 1.111 | -2.985 | -0.145 | -3.066 |
13 | -3.622 | -4.525 | 1.357 | -2.546 |
14 | -3.783 | -3.484 | 1.313 | -1.473 |
15 | 0.123 | -0.354 | -1.066 | 0.6 |
16 | -1.313 | 1.114 | -0.956 | -1.201 |
17 | 1.187 | -1.706 | -1.162 | -1.473 |
P-value | Threshold |
---|---|
0.001 | 3.92816 |
0.0005 | 4.91996 |
0.0001 | 6.98056 |