MotifTHB.H12CORE.0.P.B
Gene (human)THRB
(GeneCards)
Gene synonyms (human)ERBA2, NR1A2, THR1
Gene (mouse)Thrb
Gene synonyms (mouse)Erba2, Nr1a2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusvRGKKYRnnYvAGGhSA
GC content55.82%
Information content (bits; total / per base)13.038 / 0.767
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.882 0.888 0.762 0.773 0.907 0.914 4.323 4.414 301.77 343.051
Mouse 1 (5) 0.709 0.763 0.661 0.744 0.675 0.742 2.62 3.156 79.215 120.509

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.861 0.818 0.79 0.746 0.714 0.684
best 0.958 0.945 0.897 0.871 0.838 0.802
Methyl HT-SELEX, 2 experiments median 0.921 0.895 0.855 0.821 0.783 0.752
best 0.958 0.945 0.897 0.871 0.83 0.8
Non-Methyl HT-SELEX, 4 experiments median 0.715 0.678 0.659 0.631 0.61 0.594
best 0.947 0.927 0.896 0.864 0.838 0.802
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyT3R (NR1A) {2.1.2.2} (TFClass)
TFClass IDTFClass: 2.1.2.2.2
HGNCHGNC:11799
MGIMGI:98743
EntrezGene (human)GeneID:7068
(SSTAR profile)
EntrezGene (mouse)GeneID:21834
(SSTAR profile)
UniProt ID (human)THB_HUMAN
UniProt ID (mouse)THB_MOUSE
UniProt AC (human)P10828
(TFClass)
UniProt AC (mouse)P37242
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01295.0150.0436.0119.0
02521.015.0450.014.0
0368.012.0859.061.0
04117.010.0729.0144.0
0516.0122.0170.0692.0
0649.0704.0119.0128.0
07796.043.0102.059.0
08162.0310.0227.0301.0
09175.0384.0181.0260.0
1033.0298.084.0585.0
11242.0209.0490.059.0
12763.011.0216.010.0
135.01.0976.018.0
144.06.0934.056.0
15283.0175.085.0457.0
1666.0765.095.074.0
17823.044.077.056.0
PFM
ACGT
010.2950.150.4360.119
020.5210.0150.450.014
030.0680.0120.8590.061
040.1170.010.7290.144
050.0160.1220.170.692
060.0490.7040.1190.128
070.7960.0430.1020.059
080.1620.310.2270.301
090.1750.3840.1810.26
100.0330.2980.0840.585
110.2420.2090.490.059
120.7630.0110.2160.01
130.0050.0010.9760.018
140.0040.0060.9340.056
150.2830.1750.0850.457
160.0660.7650.0950.074
170.8230.0440.0770.056
PWM
ACGT
010.164-0.5060.553-0.735
020.731-2.7110.585-2.773
03-1.284-2.9091.229-1.39
04-0.752-3.0661.066-0.547
05-2.653-0.71-0.3821.014
06-1.6021.031-0.735-0.663
071.153-1.728-0.887-1.422
08-0.430.214-0.0960.184
09-0.3540.427-0.320.039
10-1.9810.175-1.0770.846
11-0.032-0.1780.67-1.422
121.111-2.985-0.145-3.066
13-3.622-4.5251.357-2.546
14-3.783-3.4841.313-1.473
150.123-0.354-1.0660.6
16-1.3131.114-0.956-1.201
171.187-1.706-1.162-1.473
Standard thresholds
P-value Threshold
0.001 3.92816
0.0005 4.91996
0.0001 6.98056