THAP1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	THAP1.H12CORE.0.P.B
Gene (human)	THAP1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Thap1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	23
Consensus	nbvSCCMYbYYbvnbvhKSGMdv
GC content	62.87%
Information content (bits; total / per base)	11.843 / 0.515
Data sources	ChIP-Seq
Aligned words	409

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.776	0.832	0.669	0.745	0.78	0.843	3.678	5.125	50.42	61.119
Mouse	2 (10)	0.725	0.773	0.642	0.686	0.653	0.781	3.576	5.757	17.607	31.201

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2CH THAP-type zinc finger factors {2.9} (TFClass)
TF family	THAP {2.9.1} (TFClass)
TF subfamily	{2.9.1.0} (TFClass)
TFClass ID	TFClass: 2.9.1.0.1
HGNC	HGNC:20856
MGI	MGI:1921004
EntrezGene (human)	GeneID:55145 (SSTAR profile)
EntrezGene (mouse)	GeneID:73754 (SSTAR profile)
UniProt ID (human)	THAP1_HUMAN
UniProt ID (mouse)	THAP1_MOUSE
UniProt AC (human)	Q9NVV9 (TFClass)
UniProt AC (mouse)	Q8CHW1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	THAP1.H12CORE.0.P.B.pcm
PWM	THAP1.H12CORE.0.P.B.pwm
PFM	THAP1.H12CORE.0.P.B.pfm
Alignment	THAP1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	THAP1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	THAP1.H12CORE.0.P.B_jaspar_format.txt
MEME format	THAP1.H12CORE.0.P.B_meme_format.meme
Transfac format	THAP1.H12CORE.0.P.B_transfac_format.txt
Homer format	THAP1.H12CORE.0.P.B_homer_format_0.001.txt THAP1.H12CORE.0.P.B_homer_format_0.0005.txt THAP1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	45.0	76.0	243.0	45.0
02	39.0	237.0	86.0	47.0
03	63.0	221.0	97.0	28.0
04	36.0	53.0	274.0	46.0
05	12.0	332.0	57.0	8.0
06	18.0	360.0	10.0	21.0
07	268.0	66.0	35.0	40.0
08	27.0	63.0	46.0	273.0
09	28.0	209.0	96.0	76.0
10	28.0	73.0	46.0	262.0
11	15.0	110.0	8.0	276.0
12	45.0	81.0	137.0	146.0
13	82.0	96.0	189.0	42.0
14	74.0	131.0	79.0	125.0
15	53.0	66.0	65.0	225.0
16	84.0	147.0	134.0	44.0
17	105.0	180.0	22.0	102.0
18	27.0	25.0	276.0	81.0
19	24.0	56.0	307.0	22.0
20	4.0	63.0	317.0	25.0
21	35.0	319.0	29.0	26.0
22	216.0	18.0	117.0	58.0
23	105.0	80.0	182.0	42.0

PFM

	A	C	G	T
01	0.11	0.186	0.594	0.11
02	0.095	0.579	0.21	0.115
03	0.154	0.54	0.237	0.068
04	0.088	0.13	0.67	0.112
05	0.029	0.812	0.139	0.02
06	0.044	0.88	0.024	0.051
07	0.655	0.161	0.086	0.098
08	0.066	0.154	0.112	0.667
09	0.068	0.511	0.235	0.186
10	0.068	0.178	0.112	0.641
11	0.037	0.269	0.02	0.675
12	0.11	0.198	0.335	0.357
13	0.2	0.235	0.462	0.103
14	0.181	0.32	0.193	0.306
15	0.13	0.161	0.159	0.55
16	0.205	0.359	0.328	0.108
17	0.257	0.44	0.054	0.249
18	0.066	0.061	0.675	0.198
19	0.059	0.137	0.751	0.054
20	0.01	0.154	0.775	0.061
21	0.086	0.78	0.071	0.064
22	0.528	0.044	0.286	0.142
23	0.257	0.196	0.445	0.103

PWM

	A	C	G	T
01	-0.802	-0.292	0.857	-0.802
02	-0.941	0.832	-0.17	-0.76
03	-0.475	0.763	-0.052	-1.258
04	-1.018	-0.644	0.977	-0.781
05	-2.039	1.168	-0.573	-2.39
06	-1.671	1.248	-2.199	-1.528
07	0.955	-0.43	-1.045	-0.916
08	-1.292	-0.475	-0.781	0.973
09	-1.258	0.707	-0.062	-0.292
10	-1.258	-0.331	-0.781	0.932
11	-1.838	0.072	-2.39	0.984
12	-0.802	-0.229	0.289	0.352
13	-0.217	-0.062	0.608	-0.869
14	-0.318	0.245	-0.254	0.198
15	-0.644	-0.43	-0.445	0.781
16	-0.193	0.359	0.267	-0.824
17	0.026	0.559	-1.485	-0.002
18	-1.292	-1.365	0.984	-0.229
19	-1.403	-0.59	1.09	-1.485
20	-2.937	-0.475	1.122	-1.365
21	-1.045	1.128	-1.224	-1.328
22	0.74	-1.671	0.133	-0.556
23	0.026	-0.241	0.57	-0.869

Standard thresholds

P-value	Threshold
0.001	4.36041
0.0005	5.20376
0.0001	6.99651