MotifTHA.H12INVIVO.2.S.B
Gene (human)THRA
(GeneCards)
Gene synonyms (human)EAR7, ERBA1, NR1A1, THRA1, THRA2
Gene (mouse)Thra
Gene synonyms (mouse)C-erba-alpha, Nr1a1
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length16
ConsensusdMCYbRTRAGGTCAhv
GC content47.36%
Information content (bits; total / per base)18.012 / 1.126
Data sourcesHT-SELEX
Aligned words1363

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.78 0.822 0.597 0.645 0.726 0.777 1.985 2.255 20.523 72.337
Mouse 2 (12) 0.752 0.771 0.575 0.596 0.672 0.687 1.647 1.769 56.7 80.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.778 0.779 0.63 0.65 0.557 0.584
best 0.851 0.849 0.67 0.692 0.577 0.609
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyT3R (NR1A) {2.1.2.2} (TFClass)
TFClass IDTFClass: 2.1.2.2.1
HGNCHGNC:11796
MGIMGI:98742
EntrezGene (human)GeneID:7067
(SSTAR profile)
EntrezGene (mouse)GeneID:21833
(SSTAR profile)
UniProt ID (human)THA_HUMAN
UniProt ID (mouse)THA_MOUSE
UniProt AC (human)P10827
(TFClass)
UniProt AC (mouse)P63058
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 2 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01700.0137.0143.0383.0
02111.751091.7564.7594.75
03114.01131.051.067.0
0482.0284.049.0948.0
05105.0482.0253.0523.0
06827.0101.0276.0159.0
074.0119.07.01233.0
08874.069.0408.012.0
091357.00.06.00.0
100.00.01363.00.0
110.00.01363.00.0
1241.00.00.01322.0
131.01358.02.02.0
141335.01.027.00.0
15253.25601.2581.25427.25
16289.5288.5570.5214.5
PFM
ACGT
010.5140.1010.1050.281
020.0820.8010.0480.07
030.0840.830.0370.049
040.060.2080.0360.696
050.0770.3540.1860.384
060.6070.0740.2020.117
070.0030.0870.0050.905
080.6410.0510.2990.009
090.9960.00.0040.0
100.00.01.00.0
110.00.01.00.0
120.030.00.00.97
130.0010.9960.0010.001
140.9790.0010.020.0
150.1860.4410.060.313
160.2120.2120.4190.157
PWM
ACGT
010.717-0.903-0.8610.116
02-1.1041.161-1.638-1.266
03-1.0851.196-1.87-1.605
04-1.408-0.181-1.9081.02
05-1.1650.345-0.2960.427
060.884-1.204-0.21-0.756
07-4.078-1.042-3.6611.282
080.939-1.5770.179-3.211
091.378-5.246-3.782-5.246
10-5.246-5.2461.382-5.246
11-5.246-5.2461.382-5.246
12-2.08-5.246-5.2461.352
13-4.8051.379-4.5-4.5
141.362-4.805-2.476-5.246
15-0.2950.566-1.4170.225
16-0.162-0.1660.513-0.46
Standard thresholds
P-value Threshold
0.001 0.22606
0.0005 1.81101
0.0001 5.10651