| Motif | THA.H12INVIVO.1.PS.A |
| Gene (human) | THRA (GeneCards) |
| Gene synonyms (human) | EAR7, ERBA1, NR1A1, THRA1, THRA2 |
| Gene (mouse) | Thra |
| Gene synonyms (mouse) | C-erba-alpha, Nr1a1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | A |
| Motif | THA.H12INVIVO.1.PS.A |
| Gene (human) | THRA (GeneCards) |
| Gene synonyms (human) | EAR7, ERBA1, NR1A1, THRA1, THRA2 |
| Gene (mouse) | Thra |
| Gene synonyms (mouse) | C-erba-alpha, Nr1a1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | A |
| Motif length | 8 |
| Consensus | YRAGGWCA |
| GC content | 54.12% |
| Information content (bits; total / per base) | 9.6 / 1.2 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 943 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (6) | 0.82 | 0.865 | 0.7 | 0.72 | 0.819 | 0.867 | 2.417 | 2.709 | 39.824 | 139.125 |
| Mouse | 2 (12) | 0.797 | 0.816 | 0.646 | 0.67 | 0.773 | 0.785 | 2.047 | 2.082 | 158.806 | 196.125 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.782 | 0.77 | 0.639 | 0.65 | 0.563 | 0.586 |
| best | 0.851 | 0.838 | 0.679 | 0.692 | 0.583 | 0.611 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Thyroid hormone receptor-related {2.1.2} (TFClass) |
| TF subfamily | T3R (NR1A) {2.1.2.2} (TFClass) |
| TFClass ID | TFClass: 2.1.2.2.1 |
| HGNC | HGNC:11796 |
| MGI | MGI:98742 |
| EntrezGene (human) | GeneID:7067 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21833 (SSTAR profile) |
| UniProt ID (human) | THA_HUMAN |
| UniProt ID (mouse) | THA_MOUSE |
| UniProt AC (human) | P10827 (TFClass) |
| UniProt AC (mouse) | P63058 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 2 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | THA.H12INVIVO.1.PS.A.pcm |
| PWM | THA.H12INVIVO.1.PS.A.pwm |
| PFM | THA.H12INVIVO.1.PS.A.pfm |
| Alignment | THA.H12INVIVO.1.PS.A.words.tsv |
| Threshold to P-value map | THA.H12INVIVO.1.PS.A.thr |
| Motif in other formats | |
| JASPAR format | THA.H12INVIVO.1.PS.A_jaspar_format.txt |
| MEME format | THA.H12INVIVO.1.PS.A_meme_format.meme |
| Transfac format | THA.H12INVIVO.1.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 97.0 | 233.0 | 55.0 | 558.0 |
| 02 | 243.0 | 141.0 | 521.0 | 38.0 |
| 03 | 685.0 | 3.0 | 244.0 | 11.0 |
| 04 | 8.0 | 1.0 | 930.0 | 4.0 |
| 05 | 14.0 | 4.0 | 904.0 | 21.0 |
| 06 | 322.0 | 56.0 | 27.0 | 538.0 |
| 07 | 9.0 | 913.0 | 16.0 | 5.0 |
| 08 | 903.0 | 26.0 | 9.0 | 5.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.103 | 0.247 | 0.058 | 0.592 |
| 02 | 0.258 | 0.15 | 0.552 | 0.04 |
| 03 | 0.726 | 0.003 | 0.259 | 0.012 |
| 04 | 0.008 | 0.001 | 0.986 | 0.004 |
| 05 | 0.015 | 0.004 | 0.959 | 0.022 |
| 06 | 0.341 | 0.059 | 0.029 | 0.571 |
| 07 | 0.01 | 0.968 | 0.017 | 0.005 |
| 08 | 0.958 | 0.028 | 0.01 | 0.005 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.878 | -0.012 | -1.432 | 0.857 |
| 02 | 0.03 | -0.509 | 0.789 | -1.788 |
| 03 | 1.062 | -3.92 | 0.034 | -2.927 |
| 04 | -3.197 | -4.472 | 1.367 | -3.727 |
| 05 | -2.716 | -3.727 | 1.339 | -2.347 |
| 06 | 0.31 | -1.415 | -2.113 | 0.821 |
| 07 | -3.099 | 1.349 | -2.596 | -3.566 |
| 08 | 1.338 | -2.148 | -3.099 | -3.566 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.836285 |
| 0.0005 | 5.883205 |
| 0.0001 | 7.588255 |