MotifTHA.H12INVIVO.0.P.B
Gene (human)THRA
(GeneCards)
Gene synonyms (human)EAR7, ERBA1, NR1A1, THRA1, THRA2
Gene (mouse)Thra
Gene synonyms (mouse)C-erba-alpha, Nr1a1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusvRGGKSRnnYvAGGhSA
GC content57.24%
Information content (bits; total / per base)13.629 / 0.802
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.922 0.966 0.888 0.935 0.95 0.984 5.558 6.735 78.678 275.0
Mouse 2 (12) 0.919 0.951 0.876 0.907 0.914 0.946 4.427 4.539 408.165 461.42

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.619 0.593 0.577 0.561 0.542 0.539
best 0.65 0.618 0.604 0.58 0.557 0.552
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyT3R (NR1A) {2.1.2.2} (TFClass)
TFClass IDTFClass: 2.1.2.2.1
HGNCHGNC:11796
MGIMGI:98742
EntrezGene (human)GeneID:7067
(SSTAR profile)
EntrezGene (mouse)GeneID:21833
(SSTAR profile)
UniProt ID (human)THA_HUMAN
UniProt ID (mouse)THA_MOUSE
UniProt AC (human)P10827
(TFClass)
UniProt AC (mouse)P63058
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 2 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01284.0196.0393.0127.0
02521.022.0441.016.0
0391.04.0866.039.0
0445.012.0830.0113.0
0532.0109.0230.0629.0
0630.0720.0126.0124.0
07807.054.079.060.0
08162.0235.0292.0311.0
09171.0381.0224.0224.0
1038.0304.070.0588.0
11226.0267.0427.080.0
12745.05.0241.09.0
130.00.0995.05.0
147.09.0966.018.0
15469.0167.071.0293.0
1644.0794.092.070.0
17836.048.061.055.0
PFM
ACGT
010.2840.1960.3930.127
020.5210.0220.4410.016
030.0910.0040.8660.039
040.0450.0120.830.113
050.0320.1090.230.629
060.030.720.1260.124
070.8070.0540.0790.06
080.1620.2350.2920.311
090.1710.3810.2240.224
100.0380.3040.070.588
110.2260.2670.4270.08
120.7450.0050.2410.009
130.00.00.9950.005
140.0070.0090.9660.018
150.4690.1670.0710.293
160.0440.7940.0920.07
170.8360.0480.0610.055
PWM
ACGT
010.127-0.2410.45-0.671
020.731-2.3620.565-2.653
03-0.999-3.7831.238-1.821
04-1.684-2.9091.195-0.786
05-2.01-0.821-0.0830.919
06-2.0711.053-0.678-0.694
071.167-1.508-1.137-1.406
08-0.43-0.0610.1540.217
09-0.3770.419-0.109-0.109
10-1.8460.194-1.2550.851
11-0.10.0650.532-1.125
121.087-3.622-0.036-3.156
13-4.982-4.9821.376-3.622
14-3.362-3.1561.347-2.546
150.626-0.4-1.2420.158
16-1.7061.151-0.988-1.255
171.202-1.622-1.39-1.49
Standard thresholds
P-value Threshold
0.001 3.67806
0.0005 4.72991
0.0001 6.90516