MotifTHA.H12INVITRO.1.PS.A
Gene (human)THRA
(GeneCards)
Gene synonyms (human)EAR7, ERBA1, NR1A1, THRA1, THRA2
Gene (mouse)Thra
Gene synonyms (mouse)C-erba-alpha, Nr1a1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length8
ConsensusYRAGGWCA
GC content54.22%
Information content (bits; total / per base)9.964 / 1.245
Data sourcesChIP-Seq + HT-SELEX
Aligned words980

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.821 0.866 0.7 0.717 0.817 0.868 2.412 2.705 40.658 138.018
Mouse 2 (12) 0.798 0.816 0.647 0.67 0.771 0.784 2.044 2.079 154.956 192.481

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.783 0.771 0.649 0.655 0.573 0.591
best 0.852 0.839 0.688 0.697 0.593 0.616
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyT3R (NR1A) {2.1.2.2} (TFClass)
TFClass IDTFClass: 2.1.2.2.1
HGNCHGNC:11796
MGIMGI:98742
EntrezGene (human)GeneID:7067
(SSTAR profile)
EntrezGene (mouse)GeneID:21833
(SSTAR profile)
UniProt ID (human)THA_HUMAN
UniProt ID (mouse)THA_MOUSE
UniProt AC (human)P10827
(TFClass)
UniProt AC (mouse)P63058
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 2 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
0195.0251.058.0576.0
02263.0145.0538.034.0
03721.02.0249.08.0
044.00.0972.04.0
053.00.0965.012.0
06315.068.035.0562.0
0715.0946.010.09.0
08963.07.05.05.0
PFM
ACGT
010.0970.2560.0590.588
020.2680.1480.5490.035
030.7360.0020.2540.008
040.0040.00.9920.004
050.0030.00.9850.012
060.3210.0690.0360.573
070.0150.9650.010.009
080.9830.0070.0050.005
PWM
ACGT
01-0.9360.024-1.4190.851
020.07-0.520.783-1.932
031.075-4.1940.016-3.234
04-3.764-4.9651.373-3.764
05-3.956-4.9651.366-2.889
060.25-1.264-1.9050.826
07-2.6921.346-3.047-3.136
081.364-3.342-3.603-3.603
Standard thresholds
P-value Threshold
0.001 4.722795
0.0005 5.96082
0.0001 7.635625