MotifTGIF2.H12INVITRO.0.S.B
Gene (human)TGIF2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Tgif2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length16
ConsensusnnhTGACAGSTRWYdn
GC content48.58%
Information content (bits; total / per base)16.022 / 1.001
Data sourcesHT-SELEX
Aligned words2499

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.69 0.752 0.539 0.607 0.634 0.679 1.722 1.852 51.42 83.921
Mouse 1 (6) 0.886 0.887 0.807 0.809 0.876 0.892 3.343 3.416 76.638 169.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.974 0.958 0.951 0.933 0.889 0.853
best 0.995 0.994 0.98 0.968 0.964 0.947
Methyl HT-SELEX, 2 experiments median 0.974 0.958 0.96 0.938 0.932 0.906
best 0.986 0.977 0.977 0.964 0.959 0.941
Non-Methyl HT-SELEX, 4 experiments median 0.968 0.948 0.941 0.919 0.846 0.832
best 0.995 0.994 0.98 0.968 0.964 0.947

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.815 0.604 0.771 0.559
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyTGIF {3.1.4.6} (TFClass)
TFClass IDTFClass: 3.1.4.6.2
HGNCHGNC:15764
MGIMGI:1915299
EntrezGene (human)GeneID:60436
(SSTAR profile)
EntrezGene (mouse)GeneID:228839
(SSTAR profile)
UniProt ID (human)TGIF2_HUMAN
UniProt ID (mouse)TGIF2_MOUSE
UniProt AC (human)Q9GZN2
(TFClass)
UniProt AC (mouse)Q8C0Y1
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01816.0517.0645.0521.0
02820.25414.25569.25695.25
03897.0343.0269.0990.0
0419.08.06.02466.0
050.00.02499.00.0
062472.00.06.021.0
072.02497.00.00.0
082493.01.05.00.0
093.036.02394.066.0
10114.01870.0427.088.0
11133.0191.0114.02061.0
12270.0151.01866.0212.0
13308.0231.0241.01719.0
14170.01790.0222.0317.0
151296.75358.75402.75440.75
16534.75759.75591.75612.75
PFM
ACGT
010.3270.2070.2580.208
020.3280.1660.2280.278
030.3590.1370.1080.396
040.0080.0030.0020.987
050.00.01.00.0
060.9890.00.0020.008
070.0010.9990.00.0
080.9980.00.0020.0
090.0010.0140.9580.026
100.0460.7480.1710.035
110.0530.0760.0460.825
120.1080.060.7470.085
130.1230.0920.0960.688
140.0680.7160.0890.127
150.5190.1440.1610.176
160.2140.3040.2370.245
PWM
ACGT
010.266-0.1890.032-0.181
020.272-0.409-0.0930.107
030.361-0.597-0.8390.459
04-3.398-4.142-4.3671.371
05-5.77-5.771.384-5.77
061.373-5.77-4.367-3.307
07-5.0651.383-5.77-5.77
081.382-5.357-4.501-5.77
09-4.84-2.8041.341-2.222
10-1.6871.094-0.379-1.941
11-1.536-1.178-1.6871.191
12-0.835-1.411.092-1.075
13-0.704-0.99-0.9481.01
14-1.2931.051-1.029-0.675
150.729-0.552-0.437-0.348
16-0.1550.195-0.054-0.019
Standard thresholds
P-value Threshold
0.001 1.53436
0.0005 3.00851
0.0001 6.09661