TGIF1.H12INVIVO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TGIF1.H12INVIVO.1.S.B
Gene (human)	TGIF1 (GeneCards)
Gene synonyms (human)	TGIF
Gene (mouse)	Tgif1
Gene synonyms (mouse)	Tgif
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	17
Consensus	nnhTGACAGvTKYYRnn
GC content	45.36%
Information content (bits; total / per base)	15.572 / 0.916
Data sources	HT-SELEX
Aligned words	511

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (17)	0.81	0.877	0.655	0.743	0.767	0.853	2.258	3.006	111.569	306.678

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.723	0.696	0.678	0.651	0.623	0.609
Overall, 4 experiments	best	0.962	0.942	0.941	0.912	0.881	0.855
Methyl HT-SELEX, 1 experiments	median	0.868	0.821	0.815	0.763	0.722	0.695
Methyl HT-SELEX, 1 experiments	best	0.868	0.821	0.815	0.763	0.722	0.695
Non-Methyl HT-SELEX, 3 experiments	median	0.579	0.571	0.541	0.539	0.523	0.524
Non-Methyl HT-SELEX, 3 experiments	best	0.962	0.942	0.941	0.912	0.881	0.855

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	TGIF {3.1.4.6} (TFClass)
TFClass ID	TFClass: 3.1.4.6.1
HGNC	HGNC:11776
MGI	MGI:1194497
EntrezGene (human)	GeneID:7050 (SSTAR profile)
EntrezGene (mouse)	GeneID:21815 (SSTAR profile)
UniProt ID (human)	TGIF1_HUMAN
UniProt ID (mouse)	TGIF1_MOUSE
UniProt AC (human)	Q15583 (TFClass)
UniProt AC (mouse)	P70284 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	TGIF1.H12INVIVO.1.S.B.pcm
PWM	TGIF1.H12INVIVO.1.S.B.pwm
PFM	TGIF1.H12INVIVO.1.S.B.pfm
Alignment	TGIF1.H12INVIVO.1.S.B.words.tsv
Threshold to P-value map	TGIF1.H12INVIVO.1.S.B.thr
Motif in other formats
JASPAR format	TGIF1.H12INVIVO.1.S.B_jaspar_format.txt
MEME format	TGIF1.H12INVIVO.1.S.B_meme_format.meme
Transfac format	TGIF1.H12INVIVO.1.S.B_transfac_format.txt
Homer format	TGIF1.H12INVIVO.1.S.B_homer_format_0.001.txt TGIF1.H12INVIVO.1.S.B_homer_format_0.0005.txt TGIF1.H12INVIVO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	156.25	97.25	121.25	136.25
02	155.0	73.0	143.0	140.0
03	166.0	110.0	57.0	178.0
04	0.0	0.0	0.0	511.0
05	0.0	0.0	511.0	0.0
06	494.0	0.0	0.0	17.0
07	0.0	511.0	0.0	0.0
08	511.0	0.0	0.0	0.0
09	6.0	11.0	440.0	54.0
10	78.0	227.0	169.0	37.0
11	19.0	56.0	26.0	410.0
12	50.0	27.0	380.0	54.0
13	43.0	44.0	30.0	394.0
14	41.0	347.0	51.0	72.0
15	360.0	26.0	63.0	62.0
16	152.0	151.0	56.0	152.0
17	171.75	110.75	101.75	126.75

PFM

	A	C	G	T
01	0.306	0.19	0.237	0.267
02	0.303	0.143	0.28	0.274
03	0.325	0.215	0.112	0.348
04	0.0	0.0	0.0	1.0
05	0.0	0.0	1.0	0.0
06	0.967	0.0	0.0	0.033
07	0.0	1.0	0.0	0.0
08	1.0	0.0	0.0	0.0
09	0.012	0.022	0.861	0.106
10	0.153	0.444	0.331	0.072
11	0.037	0.11	0.051	0.802
12	0.098	0.053	0.744	0.106
13	0.084	0.086	0.059	0.771
14	0.08	0.679	0.1	0.141
15	0.705	0.051	0.123	0.121
16	0.297	0.295	0.11	0.297
17	0.336	0.217	0.199	0.248

PWM

	A	C	G	T
01	0.199	-0.269	-0.052	0.064
02	0.191	-0.551	0.111	0.091
03	0.259	-0.148	-0.792	0.328
04	-4.418	-4.418	-4.418	1.377
05	-4.418	-4.418	1.377	-4.418
06	1.343	-4.418	-4.418	-1.941
07	-4.418	1.377	-4.418	-4.418
08	1.377	-4.418	-4.418	-4.418
09	-2.839	-2.332	1.228	-0.845
10	-0.486	0.57	0.277	-1.21
11	-1.839	-0.809	-1.546	1.158
12	-0.919	-1.51	1.082	-0.845
13	-1.065	-1.043	-1.41	1.118
14	-1.111	0.992	-0.9	-0.564
15	1.028	-1.546	-0.695	-0.71
16	0.172	0.165	-0.809	0.172
17	0.293	-0.141	-0.224	-0.008

Standard thresholds

P-value	Threshold
0.001	2.46041
0.0005	3.78526
0.0001	6.51576