TFEC.H12INVITRO.0.M.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TFEC.H12INVITRO.0.M.B
Gene (human)	TFEC (GeneCards)
Gene synonyms (human)	BHLHE34, TCFEC, TFECL
Gene (mouse)	Tfec
Gene synonyms (mouse)	Tcfec
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	ndvGTCACATGAY
GC content	48.62%
Information content (bits; total / per base)	17.356 / 1.335
Data sources	Methyl-HT-SELEX
Aligned words	9905

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.999	0.999	0.999	0.999	0.998	0.997
Overall, 4 experiments	best	1.0	1.0	1.0	1.0	1.0	0.999
Methyl HT-SELEX, 2 experiments	median	1.0	0.999	1.0	0.999	0.998	0.997
Methyl HT-SELEX, 2 experiments	best	1.0	1.0	1.0	1.0	1.0	0.999
Non-Methyl HT-SELEX, 2 experiments	median	0.998	0.997	0.998	0.996	0.997	0.995
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.999	0.998	0.999	0.998

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.817	0.642	0.809	0.569

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	TFE3 {1.2.6.1} (TFClass)
TFClass ID	TFClass: 1.2.6.1.3
HGNC	HGNC:11754
MGI	MGI:1333760
EntrezGene (human)	GeneID:22797 (SSTAR profile)
EntrezGene (mouse)	GeneID:21426 (SSTAR profile)
UniProt ID (human)	TFEC_HUMAN
UniProt ID (mouse)	TFEC_MOUSE
UniProt AC (human)	O14948 (TFClass)
UniProt AC (mouse)	Q9WTW4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	TFEC.H12INVITRO.0.M.B.pcm
PWM	TFEC.H12INVITRO.0.M.B.pwm
PFM	TFEC.H12INVITRO.0.M.B.pfm
Alignment	TFEC.H12INVITRO.0.M.B.words.tsv
Threshold to P-value map	TFEC.H12INVITRO.0.M.B.thr
Motif in other formats
JASPAR format	TFEC.H12INVITRO.0.M.B_jaspar_format.txt
MEME format	TFEC.H12INVITRO.0.M.B_meme_format.meme
Transfac format	TFEC.H12INVITRO.0.M.B_transfac_format.txt
Homer format	TFEC.H12INVITRO.0.M.B_homer_format_0.001.txt TFEC.H12INVITRO.0.M.B_homer_format_0.0005.txt TFEC.H12INVITRO.0.M.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2495.5	2848.5	2099.5	2461.5
02	3832.0	1423.0	2073.0	2577.0
03	4262.0	773.0	4125.0	745.0
04	1587.0	0.0	8318.0	0.0
05	0.0	0.0	0.0	9905.0
06	0.0	9905.0	0.0	0.0
07	9905.0	0.0	0.0	0.0
08	0.0	9840.0	0.0	65.0
09	6037.0	1.0	3867.0	0.0
10	0.0	0.0	0.0	9905.0
11	0.0	1.0	9904.0	0.0
12	9377.75	178.75	183.75	164.75
13	141.75	6859.75	201.75	2701.75

PFM

	A	C	G	T
01	0.252	0.288	0.212	0.249
02	0.387	0.144	0.209	0.26
03	0.43	0.078	0.416	0.075
04	0.16	0.0	0.84	0.0
05	0.0	0.0	0.0	1.0
06	0.0	1.0	0.0	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.993	0.0	0.007
09	0.609	0.0	0.39	0.0
10	0.0	0.0	0.0	1.0
11	0.0	0.0	1.0	0.0
12	0.947	0.018	0.019	0.017
13	0.014	0.693	0.02	0.273

PWM

	A	C	G	T
01	0.008	0.14	-0.165	-0.006
02	0.436	-0.553	-0.178	0.04
03	0.543	-1.162	0.51	-1.199
04	-0.444	-6.982	1.211	-6.982
05	-6.982	-6.982	-6.982	1.386
06	-6.982	1.386	-6.982	-6.982
07	1.386	-6.982	-6.982	-6.982
08	-6.982	1.379	-6.982	-3.606
09	0.891	-6.621	0.445	-6.982
10	-6.982	-6.982	-6.982	1.386
11	-6.982	-6.621	1.385	-6.982
12	1.331	-2.617	-2.589	-2.697
13	-2.845	1.018	-2.497	0.087

Standard thresholds

P-value	Threshold
0.001	-3.13864
0.0005	-0.79639
0.0001	3.54693