MotifTFEB.H12INVIVO.1.P.C
Gene (human)TFEB
(GeneCards)
Gene synonyms (human)BHLHE35
Gene (mouse)Tfeb
Gene synonyms (mouse)Tcfeb
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length11
ConsensusdRKCACRWGvb
GC content50.06%
Information content (bits; total / per base)10.69 / 0.972
Data sourcesChIP-Seq
Aligned words1005

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.885 0.896 0.789 0.81 0.856 0.861 2.931 2.971 251.377 275.337

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.999 0.997 0.997 0.996 0.992 0.987
best 1.0 0.999 1.0 0.999 0.999 0.999
Methyl HT-SELEX, 2 experiments median 0.999 0.999 0.999 0.998 0.998 0.997
best 1.0 0.999 1.0 0.999 0.999 0.999
Non-Methyl HT-SELEX, 4 experiments median 0.998 0.996 0.997 0.994 0.972 0.969
best 0.999 0.999 0.998 0.997 0.995 0.992

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.748 0.366 0.683 0.487
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyTFE3 {1.2.6.1} (TFClass)
TFClass IDTFClass: 1.2.6.1.2
HGNCHGNC:11753
MGIMGI:103270
EntrezGene (human)GeneID:7942
(SSTAR profile)
EntrezGene (mouse)GeneID:21425
(SSTAR profile)
UniProt ID (human)TFEB_HUMAN
UniProt ID (mouse)TFEB_MOUSE
UniProt AC (human)P19484
(TFClass)
UniProt AC (mouse)Q9R210
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01489.0101.0250.0165.0
02356.072.0551.026.0
0351.072.0146.0736.0
040.01000.04.01.0
05939.020.01.045.0
069.0894.076.026.0
07715.038.0238.014.0
08135.013.084.0773.0
091.08.0989.07.0
10536.0161.0234.074.0
11135.0435.0147.0288.0
PFM
ACGT
010.4870.10.2490.164
020.3540.0720.5480.026
030.0510.0720.1450.732
040.00.9950.0040.001
050.9340.020.0010.045
060.0090.890.0760.026
070.7110.0380.2370.014
080.1340.0130.0840.769
090.0010.0080.9840.007
100.5330.160.2330.074
110.1340.4330.1460.287
PWM
ACGT
010.663-0.901-0.005-0.417
020.346-1.2330.782-2.211
03-1.568-1.233-0.5381.07
04-4.9861.376-3.788-4.53
051.313-2.455-4.53-1.689
06-3.161.264-1.18-2.211
071.041-1.851-0.054-2.778
08-0.615-2.844-1.0821.119
09-4.53-3.2581.365-3.367
100.754-0.441-0.071-1.206
11-0.6150.546-0.5310.136
Standard thresholds
P-value Threshold
0.001 4.59464
0.0005 5.547335
0.0001 7.3748