TFEB.H12INVITRO.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TFEB.H12INVITRO.1.P.C
Gene (human)	TFEB (GeneCards)
Gene synonyms (human)	BHLHE35
Gene (mouse)	Tfeb
Gene synonyms (mouse)	Tcfeb
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	10
Consensus	RYCACRWGvh
GC content	51.16%
Information content (bits; total / per base)	10.387 / 1.039
Data sources	ChIP-Seq
Aligned words	1006

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.884	0.895	0.795	0.814	0.848	0.854	2.879	2.929	232.036	253.658

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.999	0.998	0.997	0.995	0.992	0.987
Overall, 6 experiments	best	1.0	0.999	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	1.0	0.999	0.999	0.999	0.998	0.997
Methyl HT-SELEX, 2 experiments	best	1.0	0.999	1.0	0.999	0.999	0.999
Non-Methyl HT-SELEX, 4 experiments	median	0.998	0.996	0.996	0.994	0.972	0.969
Non-Methyl HT-SELEX, 4 experiments	best	0.999	0.999	0.998	0.997	0.996	0.992

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.724	0.335	0.644	0.453

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	TFE3 {1.2.6.1} (TFClass)
TFClass ID	TFClass: 1.2.6.1.2
HGNC	HGNC:11753
MGI	MGI:103270
EntrezGene (human)	GeneID:7942 (SSTAR profile)
EntrezGene (mouse)	GeneID:21425 (SSTAR profile)
UniProt ID (human)	TFEB_HUMAN
UniProt ID (mouse)	TFEB_MOUSE
UniProt AC (human)	P19484 (TFClass)
UniProt AC (mouse)	Q9R210 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	TFEB.H12INVITRO.1.P.C.pcm
PWM	TFEB.H12INVITRO.1.P.C.pwm
PFM	TFEB.H12INVITRO.1.P.C.pfm
Alignment	TFEB.H12INVITRO.1.P.C.words.tsv
Threshold to P-value map	TFEB.H12INVITRO.1.P.C.thr
Motif in other formats
JASPAR format	TFEB.H12INVITRO.1.P.C_jaspar_format.txt
MEME format	TFEB.H12INVITRO.1.P.C_meme_format.meme
Transfac format	TFEB.H12INVITRO.1.P.C_transfac_format.txt
Homer format	TFEB.H12INVITRO.1.P.C_homer_format_0.001.txt TFEB.H12INVITRO.1.P.C_homer_format_0.0005.txt TFEB.H12INVITRO.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	326.0	122.0	522.0	36.0
02	64.0	109.0	83.0	750.0
03	3.0	998.0	3.0	2.0
04	924.0	22.0	2.0	58.0
05	10.0	939.0	34.0	23.0
06	725.0	51.0	219.0	11.0
07	141.0	10.0	76.0	779.0
08	3.0	7.0	989.0	7.0
09	504.0	225.0	204.0	73.0
10	151.0	422.0	110.0	323.0

PFM

	A	C	G	T
01	0.324	0.121	0.519	0.036
02	0.064	0.108	0.083	0.746
03	0.003	0.992	0.003	0.002
04	0.918	0.022	0.002	0.058
05	0.01	0.933	0.034	0.023
06	0.721	0.051	0.218	0.011
07	0.14	0.01	0.076	0.774
08	0.003	0.007	0.983	0.007
09	0.501	0.224	0.203	0.073
10	0.15	0.419	0.109	0.321

PWM

	A	C	G	T
01	0.258	-0.716	0.727	-1.904
02	-1.349	-0.827	-1.095	1.088
03	-3.981	1.373	-3.981	-4.218
04	1.296	-2.368	-4.218	-1.444
05	-3.072	1.312	-1.958	-2.326
06	1.054	-1.569	-0.137	-2.99
07	-0.573	-3.072	-1.181	1.126
08	-3.981	-3.368	1.364	-3.368
09	0.692	-0.111	-0.208	-1.22
10	-0.506	0.515	-0.818	0.249

Standard thresholds

P-value	Threshold
0.001	4.669745
0.0005	5.59859
0.0001	7.370265