TFEB.H12CORE.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TFEB.H12CORE.1.P.C
Gene (human)	TFEB (GeneCards)
Gene synonyms (human)	BHLHE35
Gene (mouse)	Tfeb
Gene synonyms (mouse)	Tcfeb
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	11
Consensus	dRKCACRWGvb
GC content	50.06%
Information content (bits; total / per base)	10.69 / 0.972
Data sources	ChIP-Seq
Aligned words	1005

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.885	0.896	0.789	0.81	0.856	0.861	2.931	2.971	251.377	275.337

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.999	0.997	0.997	0.996	0.992	0.987
Overall, 6 experiments	best	1.0	0.999	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 2 experiments	median	0.999	0.999	0.999	0.998	0.998	0.997
Methyl HT-SELEX, 2 experiments	best	1.0	0.999	1.0	0.999	0.999	0.999
Non-Methyl HT-SELEX, 4 experiments	median	0.998	0.996	0.997	0.994	0.972	0.969
Non-Methyl HT-SELEX, 4 experiments	best	0.999	0.999	0.998	0.997	0.995	0.992

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.748	0.366	0.683	0.487

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	TFE3 {1.2.6.1} (TFClass)
TFClass ID	TFClass: 1.2.6.1.2
HGNC	HGNC:11753
MGI	MGI:103270
EntrezGene (human)	GeneID:7942 (SSTAR profile)
EntrezGene (mouse)	GeneID:21425 (SSTAR profile)
UniProt ID (human)	TFEB_HUMAN
UniProt ID (mouse)	TFEB_MOUSE
UniProt AC (human)	P19484 (TFClass)
UniProt AC (mouse)	Q9R210 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	TFEB.H12CORE.1.P.C.pcm
PWM	TFEB.H12CORE.1.P.C.pwm
PFM	TFEB.H12CORE.1.P.C.pfm
Alignment	TFEB.H12CORE.1.P.C.words.tsv
Threshold to P-value map	TFEB.H12CORE.1.P.C.thr
Motif in other formats
JASPAR format	TFEB.H12CORE.1.P.C_jaspar_format.txt
MEME format	TFEB.H12CORE.1.P.C_meme_format.meme
Transfac format	TFEB.H12CORE.1.P.C_transfac_format.txt
Homer format	TFEB.H12CORE.1.P.C_homer_format_0.001.txt TFEB.H12CORE.1.P.C_homer_format_0.0005.txt TFEB.H12CORE.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	489.0	101.0	250.0	165.0
02	356.0	72.0	551.0	26.0
03	51.0	72.0	146.0	736.0
04	0.0	1000.0	4.0	1.0
05	939.0	20.0	1.0	45.0
06	9.0	894.0	76.0	26.0
07	715.0	38.0	238.0	14.0
08	135.0	13.0	84.0	773.0
09	1.0	8.0	989.0	7.0
10	536.0	161.0	234.0	74.0
11	135.0	435.0	147.0	288.0

PFM

	A	C	G	T
01	0.487	0.1	0.249	0.164
02	0.354	0.072	0.548	0.026
03	0.051	0.072	0.145	0.732
04	0.0	0.995	0.004	0.001
05	0.934	0.02	0.001	0.045
06	0.009	0.89	0.076	0.026
07	0.711	0.038	0.237	0.014
08	0.134	0.013	0.084	0.769
09	0.001	0.008	0.984	0.007
10	0.533	0.16	0.233	0.074
11	0.134	0.433	0.146	0.287

PWM

	A	C	G	T
01	0.663	-0.901	-0.005	-0.417
02	0.346	-1.233	0.782	-2.211
03	-1.568	-1.233	-0.538	1.07
04	-4.986	1.376	-3.788	-4.53
05	1.313	-2.455	-4.53	-1.689
06	-3.16	1.264	-1.18	-2.211
07	1.041	-1.851	-0.054	-2.778
08	-0.615	-2.844	-1.082	1.119
09	-4.53	-3.258	1.365	-3.367
10	0.754	-0.441	-0.071	-1.206
11	-0.615	0.546	-0.531	0.136

Standard thresholds

P-value	Threshold
0.001	4.59464
0.0005	5.547335
0.0001	7.3748