MotifTFEB.H12CORE.0.SM.B
Gene (human)TFEB
(GeneCards)
Gene synonyms (human)BHLHE35
Gene (mouse)Tfeb
Gene synonyms (mouse)Tcfeb
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnnGTCACGTGMb
GC content50.17%
Information content (bits; total / per base)15.004 / 1.25
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9975

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.886 0.894 0.794 0.811 0.86 0.863 2.968 3.014 230.009 260.721

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.999 0.999 0.999 0.998 0.996 0.994
best 1.0 1.0 1.0 0.999 0.999 0.999
Methyl HT-SELEX, 2 experiments median 0.999 0.999 0.999 0.999 0.998 0.997
best 1.0 0.999 1.0 0.999 0.999 0.999
Non-Methyl HT-SELEX, 4 experiments median 0.999 0.999 0.999 0.998 0.978 0.977
best 1.0 1.0 0.999 0.999 0.998 0.997

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.797 0.532 0.831 0.655
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyTFE3 {1.2.6.1} (TFClass)
TFClass IDTFClass: 1.2.6.1.2
HGNCHGNC:11753
MGIMGI:103270
EntrezGene (human)GeneID:7942
(SSTAR profile)
EntrezGene (mouse)GeneID:21425
(SSTAR profile)
UniProt ID (human)TFEB_HUMAN
UniProt ID (mouse)TFEB_MOUSE
UniProt AC (human)P19484
(TFClass)
UniProt AC (mouse)Q9R210
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
013268.51684.52261.52760.5
022803.02146.03324.01702.0
032567.034.07372.02.0
040.03.040.09932.0
050.09971.04.00.0
069973.01.00.01.0
070.09774.03.0198.0
083121.064.06790.00.0
09102.069.025.09779.0
1010.08.09934.023.0
117261.75982.75824.75905.75
12418.53549.51192.54814.5
PFM
ACGT
010.3280.1690.2270.277
020.2810.2150.3330.171
030.2570.0030.7390.0
040.00.00.0040.996
050.01.00.00.0
061.00.00.00.0
070.00.980.00.02
080.3130.0060.6810.0
090.010.0070.0030.98
100.0010.0010.9960.002
110.7280.0990.0830.091
120.0420.3560.120.483
PWM
ACGT
010.27-0.392-0.0980.102
020.117-0.150.287-0.382
030.029-4.2311.083-6.363
04-6.989-6.154-4.0781.381
05-6.9891.385-5.982-6.989
061.385-6.628-6.989-6.628
07-6.9891.365-6.154-2.523
080.224-3.6281.001-6.989
09-3.175-3.556-4.5161.366
10-5.313-5.491.381-4.592
111.068-0.93-1.105-1.011
12-1.780.353-0.7370.657
Standard thresholds
P-value Threshold
0.001 0.70468
0.0005 2.452515
0.0001 5.734795