| Motif | TFE2.H12INVIVO.0.PS.A |
| Gene (human) | TCF3 (GeneCards) |
| Gene synonyms (human) | BHLHB21, E2A, ITF1 |
| Gene (mouse) | Tcf3 |
| Gene synonyms (mouse) | Alf2, Me2, Tcfe2a |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | TFE2.H12INVIVO.0.PS.A |
| Gene (human) | TCF3 (GeneCards) |
| Gene synonyms (human) | BHLHB21, E2A, ITF1 |
| Gene (mouse) | Tcf3 |
| Gene synonyms (mouse) | Alf2, Me2, Tcfe2a |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 10 |
| Consensus | vCASCTGbnn |
| GC content | 61.03% |
| Information content (bits; total / per base) | 9.095 / 0.91 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 829 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 8 (48) | 0.84 | 0.914 | 0.736 | 0.884 | 0.786 | 0.881 | 2.234 | 2.731 | 88.45 | 187.444 |
| Mouse | 23 (149) | 0.906 | 0.965 | 0.815 | 0.932 | 0.847 | 0.898 | 2.524 | 2.84 | 193.602 | 332.886 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.995 | 0.991 | 0.992 | 0.987 | 0.966 | 0.961 |
| best | 0.997 | 0.995 | 0.994 | 0.99 | 0.98 | 0.976 | |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | E2A {1.2.1} (TFClass) |
| TF subfamily | E2A-like {1.2.1.0} (TFClass) |
| TFClass ID | TFClass: 1.2.1.0.1 |
| HGNC | HGNC:11633 |
| MGI | MGI:98510 |
| EntrezGene (human) | GeneID:6929 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21423 (SSTAR profile) |
| UniProt ID (human) | TFE2_HUMAN |
| UniProt ID (mouse) | TFE2_MOUSE |
| UniProt AC (human) | P15923 (TFClass) |
| UniProt AC (mouse) | P15806 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 8 human, 23 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | TFE2.H12INVIVO.0.PS.A.pcm |
| PWM | TFE2.H12INVIVO.0.PS.A.pwm |
| PFM | TFE2.H12INVIVO.0.PS.A.pfm |
| Alignment | TFE2.H12INVIVO.0.PS.A.words.tsv |
| Threshold to P-value map | TFE2.H12INVIVO.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | TFE2.H12INVIVO.0.PS.A_jaspar_format.txt |
| MEME format | TFE2.H12INVIVO.0.PS.A_meme_format.meme |
| Transfac format | TFE2.H12INVIVO.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 352.0 | 213.0 | 183.0 | 81.0 |
| 02 | 29.0 | 758.0 | 26.0 | 16.0 |
| 03 | 716.0 | 44.0 | 9.0 | 60.0 |
| 04 | 5.0 | 389.0 | 295.0 | 140.0 |
| 05 | 14.0 | 800.0 | 10.0 | 5.0 |
| 06 | 5.0 | 7.0 | 2.0 | 815.0 |
| 07 | 4.0 | 5.0 | 812.0 | 8.0 |
| 08 | 25.0 | 382.0 | 244.0 | 178.0 |
| 09 | 201.0 | 191.0 | 222.0 | 215.0 |
| 10 | 187.0 | 218.0 | 249.0 | 175.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.425 | 0.257 | 0.221 | 0.098 |
| 02 | 0.035 | 0.914 | 0.031 | 0.019 |
| 03 | 0.864 | 0.053 | 0.011 | 0.072 |
| 04 | 0.006 | 0.469 | 0.356 | 0.169 |
| 05 | 0.017 | 0.965 | 0.012 | 0.006 |
| 06 | 0.006 | 0.008 | 0.002 | 0.983 |
| 07 | 0.005 | 0.006 | 0.979 | 0.01 |
| 08 | 0.03 | 0.461 | 0.294 | 0.215 |
| 09 | 0.242 | 0.23 | 0.268 | 0.259 |
| 10 | 0.226 | 0.263 | 0.3 | 0.211 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.526 | 0.027 | -0.123 | -0.927 |
| 02 | -1.918 | 1.291 | -2.021 | -2.47 |
| 03 | 1.234 | -1.52 | -2.974 | -1.22 |
| 04 | -3.443 | 0.626 | 0.351 | -0.388 |
| 05 | -2.59 | 1.345 | -2.884 | -3.443 |
| 06 | -3.443 | -3.181 | -4.039 | 1.363 |
| 07 | -3.605 | -3.443 | 1.36 | -3.072 |
| 08 | -2.058 | 0.608 | 0.162 | -0.151 |
| 09 | -0.03 | -0.081 | 0.068 | 0.036 |
| 10 | -0.102 | 0.05 | 0.182 | -0.168 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.767305 |
| 0.0005 | 5.882715 |
| 0.0001 | 7.571995 |