| Motif | TFCP2.H12RSNP.0.SM.B |
| Gene (human) | TFCP2 (GeneCards) |
| Gene synonyms (human) | LSF, SEF |
| Gene (mouse) | Tfcp2 |
| Gene synonyms (mouse) | Tcfcp2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | TFCP2.H12RSNP.0.SM.B |
| Gene (human) | TFCP2 (GeneCards) |
| Gene synonyms (human) | LSF, SEF |
| Gene (mouse) | Tfcp2 |
| Gene synonyms (mouse) | Tcfcp2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 26 |
| Consensus | ShdRhhndWWCCGGWYhdWACCGGWW |
| GC content | 51.27% |
| Information content (bits; total / per base) | 21.681 / 0.834 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 913 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 5 experiments | median | 0.995 | 0.992 | 0.984 | 0.978 | 0.944 | 0.933 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | |
| Methyl HT-SELEX, 2 experiments | median | 0.997 | 0.996 | 0.992 | 0.989 | 0.971 | 0.965 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.998 | 0.998 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.977 | 0.973 | 0.794 | 0.81 | 0.642 | 0.682 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.945 | 0.844 | 0.928 | 0.636 |
| batch 2 | 0.73 | 0.245 | 0.817 | 0.553 |
| TF superclass | Immunoglobulin fold {6} (TFClass) |
| TF class | Grainyhead domain factors {6.7} (TFClass) |
| TF family | CP2-related {6.7.2} (TFClass) |
| TF subfamily | {6.7.2.0} (TFClass) |
| TFClass ID | TFClass: 6.7.2.0.1 |
| HGNC | HGNC:11748 |
| MGI | MGI:98509 |
| EntrezGene (human) | GeneID:7024 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21422 (SSTAR profile) |
| UniProt ID (human) | TFCP2_HUMAN |
| UniProt ID (mouse) | TFCP2_MOUSE |
| UniProt AC (human) | Q12800 (TFClass) |
| UniProt AC (mouse) | Q9ERA0 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 2 |
| PCM | TFCP2.H12RSNP.0.SM.B.pcm |
| PWM | TFCP2.H12RSNP.0.SM.B.pwm |
| PFM | TFCP2.H12RSNP.0.SM.B.pfm |
| Alignment | TFCP2.H12RSNP.0.SM.B.words.tsv |
| Threshold to P-value map | TFCP2.H12RSNP.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | TFCP2.H12RSNP.0.SM.B_jaspar_format.txt |
| MEME format | TFCP2.H12RSNP.0.SM.B_meme_format.meme |
| Transfac format | TFCP2.H12RSNP.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 58.75 | 624.75 | 118.75 | 110.75 |
| 02 | 95.0 | 495.0 | 75.0 | 248.0 |
| 03 | 296.0 | 69.0 | 447.0 | 101.0 |
| 04 | 88.0 | 83.0 | 701.0 | 41.0 |
| 05 | 220.0 | 238.0 | 65.0 | 390.0 |
| 06 | 126.0 | 206.0 | 76.0 | 505.0 |
| 07 | 182.0 | 256.0 | 196.0 | 279.0 |
| 08 | 340.0 | 89.0 | 351.0 | 133.0 |
| 09 | 624.0 | 29.0 | 108.0 | 152.0 |
| 10 | 520.0 | 12.0 | 77.0 | 304.0 |
| 11 | 1.0 | 879.0 | 27.0 | 6.0 |
| 12 | 12.0 | 702.0 | 2.0 | 197.0 |
| 13 | 242.0 | 4.0 | 655.0 | 12.0 |
| 14 | 5.0 | 23.0 | 885.0 | 0.0 |
| 15 | 168.0 | 130.0 | 6.0 | 609.0 |
| 16 | 53.0 | 125.0 | 26.0 | 709.0 |
| 17 | 158.0 | 238.0 | 133.0 | 384.0 |
| 18 | 474.0 | 74.0 | 232.0 | 133.0 |
| 19 | 722.0 | 21.0 | 77.0 | 93.0 |
| 20 | 697.0 | 2.0 | 43.0 | 171.0 |
| 21 | 0.0 | 911.0 | 0.0 | 2.0 |
| 22 | 5.0 | 745.0 | 2.0 | 161.0 |
| 23 | 181.0 | 1.0 | 730.0 | 1.0 |
| 24 | 2.0 | 10.0 | 901.0 | 0.0 |
| 25 | 202.75 | 85.75 | 10.75 | 613.75 |
| 26 | 160.5 | 121.5 | 51.5 | 579.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.064 | 0.684 | 0.13 | 0.121 |
| 02 | 0.104 | 0.542 | 0.082 | 0.272 |
| 03 | 0.324 | 0.076 | 0.49 | 0.111 |
| 04 | 0.096 | 0.091 | 0.768 | 0.045 |
| 05 | 0.241 | 0.261 | 0.071 | 0.427 |
| 06 | 0.138 | 0.226 | 0.083 | 0.553 |
| 07 | 0.199 | 0.28 | 0.215 | 0.306 |
| 08 | 0.372 | 0.097 | 0.384 | 0.146 |
| 09 | 0.683 | 0.032 | 0.118 | 0.166 |
| 10 | 0.57 | 0.013 | 0.084 | 0.333 |
| 11 | 0.001 | 0.963 | 0.03 | 0.007 |
| 12 | 0.013 | 0.769 | 0.002 | 0.216 |
| 13 | 0.265 | 0.004 | 0.717 | 0.013 |
| 14 | 0.005 | 0.025 | 0.969 | 0.0 |
| 15 | 0.184 | 0.142 | 0.007 | 0.667 |
| 16 | 0.058 | 0.137 | 0.028 | 0.777 |
| 17 | 0.173 | 0.261 | 0.146 | 0.421 |
| 18 | 0.519 | 0.081 | 0.254 | 0.146 |
| 19 | 0.791 | 0.023 | 0.084 | 0.102 |
| 20 | 0.763 | 0.002 | 0.047 | 0.187 |
| 21 | 0.0 | 0.998 | 0.0 | 0.002 |
| 22 | 0.005 | 0.816 | 0.002 | 0.176 |
| 23 | 0.198 | 0.001 | 0.8 | 0.001 |
| 24 | 0.002 | 0.011 | 0.987 | 0.0 |
| 25 | 0.222 | 0.094 | 0.012 | 0.672 |
| 26 | 0.176 | 0.133 | 0.056 | 0.635 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.336 | 1.002 | -0.647 | -0.715 |
| 02 | -0.866 | 0.77 | -1.098 | 0.082 |
| 03 | 0.258 | -1.179 | 0.668 | -0.806 |
| 04 | -0.941 | -0.999 | 1.117 | -1.684 |
| 05 | -0.037 | 0.042 | -1.238 | 0.533 |
| 06 | -0.588 | -0.102 | -1.085 | 0.79 |
| 07 | -0.225 | 0.114 | -0.151 | 0.199 |
| 08 | 0.396 | -0.93 | 0.428 | -0.535 |
| 09 | 1.001 | -2.013 | -0.74 | -0.403 |
| 10 | 0.819 | -2.82 | -1.072 | 0.285 |
| 11 | -4.443 | 1.343 | -2.081 | -3.396 |
| 12 | -2.82 | 1.118 | -4.128 | -0.146 |
| 13 | 0.058 | -3.697 | 1.049 | -2.82 |
| 14 | -3.535 | -2.231 | 1.35 | -4.905 |
| 15 | -0.304 | -0.557 | -3.396 | 0.977 |
| 16 | -1.436 | -0.596 | -2.116 | 1.128 |
| 17 | -0.365 | 0.042 | -0.535 | 0.517 |
| 18 | 0.727 | -1.111 | 0.016 | -0.535 |
| 19 | 1.147 | -2.315 | -1.072 | -0.887 |
| 20 | 1.111 | -4.128 | -1.638 | -0.286 |
| 21 | -4.905 | 1.379 | -4.905 | -4.128 |
| 22 | -3.535 | 1.178 | -4.128 | -0.346 |
| 23 | -0.23 | -4.443 | 1.157 | -4.443 |
| 24 | -4.128 | -2.978 | 1.368 | -4.905 |
| 25 | -0.118 | -0.967 | -2.916 | 0.984 |
| 26 | -0.349 | -0.624 | -1.464 | 0.927 |
| P-value | Threshold |
|---|---|
| 0.001 | -0.50684 |
| 0.0005 | 1.00916 |
| 0.0001 | 4.20006 |