MotifTFCP2.H12INVIVO.1.SM.D
Gene (human)TFCP2
(GeneCards)
Gene synonyms (human)LSF, SEF
Gene (mouse)Tfcp2
Gene synonyms (mouse)Tcfcp2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length21
ConsensusnvRWCCGGYYdRAACCGGWWn
GC content50.63%
Information content (bits; total / per base)19.316 / 0.92
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words454

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.991 0.986 0.976 0.966 0.929 0.914
best 1.0 0.999 0.999 0.998 0.997 0.996
Methyl HT-SELEX, 2 experiments median 0.995 0.993 0.987 0.982 0.962 0.954
best 0.999 0.999 0.999 0.998 0.995 0.994
Non-Methyl HT-SELEX, 3 experiments median 0.957 0.949 0.781 0.791 0.641 0.674
best 1.0 0.999 0.999 0.998 0.997 0.996

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.903 0.776 0.914 0.628
batch 2 0.733 0.218 0.826 0.554
TF superclassImmunoglobulin fold {6} (TFClass)
TF classGrainyhead domain factors {6.7} (TFClass)
TF familyCP2-related {6.7.2} (TFClass)
TF subfamily {6.7.2.0} (TFClass)
TFClass IDTFClass: 6.7.2.0.1
HGNCHGNC:11748
MGIMGI:98509
EntrezGene (human)GeneID:7024
(SSTAR profile)
EntrezGene (mouse)GeneID:21422
(SSTAR profile)
UniProt ID (human)TFCP2_HUMAN
UniProt ID (mouse)TFCP2_MOUSE
UniProt AC (human)Q12800
(TFClass)
UniProt AC (mouse)Q9ERA0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 2
PCM
ACGT
01121.0122.095.0116.0
02177.2565.25161.2550.25
03306.014.068.066.0
04295.06.049.0104.0
050.0449.02.03.0
068.0330.02.0114.0
07117.04.0330.03.0
083.011.0439.01.0
0981.0104.07.0262.0
1050.077.019.0308.0
1199.043.0106.0206.0
12169.06.0239.040.0
13384.00.029.041.0
14327.01.00.0126.0
150.0448.06.00.0
160.0404.00.050.0
1778.00.0374.02.0
180.020.0434.00.0
19107.061.00.0286.0
2069.2549.2531.25304.25
21103.25143.2578.25129.25
PFM
ACGT
010.2670.2690.2090.256
020.390.1440.3550.111
030.6740.0310.150.145
040.650.0130.1080.229
050.00.9890.0040.007
060.0180.7270.0040.251
070.2580.0090.7270.007
080.0070.0240.9670.002
090.1780.2290.0150.577
100.110.170.0420.678
110.2180.0950.2330.454
120.3720.0130.5260.088
130.8460.00.0640.09
140.720.0020.00.278
150.00.9870.0130.0
160.00.890.00.11
170.1720.00.8240.004
180.00.0440.9560.0
190.2360.1340.00.63
200.1530.1080.0690.67
210.2270.3160.1720.285
PWM
ACGT
010.0630.071-0.1750.022
020.441-0.5440.347-0.798
030.983-2.002-0.503-0.533
040.947-2.726-0.823-0.086
05-4.321.365-3.484-3.235
06-2.4911.059-3.4840.004
070.03-3.0351.059-3.235
08-3.235-2.2171.343-3.817
09-0.332-0.086-2.6020.829
10-0.803-0.382-1.7230.99
11-0.135-0.949-0.0670.59
120.394-2.7260.738-1.019
131.209-4.32-1.326-0.995
141.049-3.817-4.320.103
15-4.321.363-2.726-4.32
16-4.321.26-4.32-0.803
17-0.369-4.321.183-3.484
18-4.32-1.6761.331-4.32
19-0.058-0.61-4.320.916
20-0.486-0.818-1.2550.978
21-0.0930.23-0.3660.128
Standard thresholds
P-value Threshold
0.001 0.71941
0.0005 2.15526
0.0001 5.16541