MotifTFCP2.H12INVIVO.0.SM.D
Gene (human)TFCP2
(GeneCards)
Gene synonyms (human)LSF, SEF
Gene (mouse)Tfcp2
Gene synonyms (mouse)Tcfcp2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length26
ConsensusYhdRhhndRWCYRGWYhdWWCCGGWW
GC content51.27%
Information content (bits; total / per base)19.764 / 0.76
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2474

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.995 0.992 0.985 0.979 0.947 0.936
best 1.0 1.0 1.0 1.0 0.999 0.999
Methyl HT-SELEX, 2 experiments median 0.997 0.996 0.992 0.989 0.973 0.967
best 1.0 1.0 1.0 0.999 0.998 0.998
Non-Methyl HT-SELEX, 3 experiments median 0.978 0.975 0.795 0.811 0.643 0.683
best 1.0 1.0 1.0 1.0 0.999 0.999

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.944 0.854 0.92 0.631
batch 2 0.749 0.234 0.801 0.541
TF superclassImmunoglobulin fold {6} (TFClass)
TF classGrainyhead domain factors {6.7} (TFClass)
TF familyCP2-related {6.7.2} (TFClass)
TF subfamily {6.7.2.0} (TFClass)
TFClass IDTFClass: 6.7.2.0.1
HGNCHGNC:11748
MGIMGI:98509
EntrezGene (human)GeneID:7024
(SSTAR profile)
EntrezGene (mouse)GeneID:21422
(SSTAR profile)
UniProt ID (human)TFCP2_HUMAN
UniProt ID (mouse)TFCP2_MOUSE
UniProt AC (human)Q12800
(TFClass)
UniProt AC (mouse)Q9ERA0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 2
PCM
ACGT
01179.51634.5321.5338.5
02265.751303.75212.75691.75
03770.0243.01174.0287.0
04250.0234.01814.0176.0
05547.0606.0245.01076.0
06369.0590.0243.01272.0
07514.0637.0478.0845.0
08912.0303.0848.0411.0
091622.089.0406.0357.0
101369.048.0297.0760.0
114.02326.0114.030.0
1277.01801.010.0586.0
13720.030.01665.059.0
1426.073.02375.00.0
15485.0382.027.01580.0
16292.0328.0106.01748.0
17442.0689.0336.01007.0
181165.0271.0691.0347.0
191838.052.0267.0317.0
201704.04.0150.0616.0
210.02456.017.01.0
2216.01971.06.0481.0
23521.05.01928.020.0
241.026.02447.00.0
25635.0184.017.01638.0
26458.75339.75156.751518.75
PFM
ACGT
010.0730.6610.130.137
020.1070.5270.0860.28
030.3110.0980.4750.116
040.1010.0950.7330.071
050.2210.2450.0990.435
060.1490.2380.0980.514
070.2080.2570.1930.342
080.3690.1220.3430.166
090.6560.0360.1640.144
100.5530.0190.120.307
110.0020.940.0460.012
120.0310.7280.0040.237
130.2910.0120.6730.024
140.0110.030.960.0
150.1960.1540.0110.639
160.1180.1330.0430.707
170.1790.2780.1360.407
180.4710.110.2790.14
190.7430.0210.1080.128
200.6890.0020.0610.249
210.00.9930.0070.0
220.0060.7970.0020.194
230.2110.0020.7790.008
240.00.0110.9890.0
250.2570.0740.0070.662
260.1850.1370.0630.614
PWM
ACGT
01-1.2290.97-0.651-0.6
02-0.8410.744-1.0610.112
030.218-0.9290.639-0.764
04-0.901-0.9671.074-1.249
05-0.122-0.02-0.9210.552
06-0.514-0.047-0.9290.719
07-0.1840.029-0.2570.311
080.387-0.710.315-0.407
090.962-1.92-0.419-0.547
100.793-2.519-0.730.205
11-4.6461.322-1.677-2.966
12-2.0621.067-3.949-0.054
130.152-2.9660.988-2.32
14-3.1-2.1141.343-5.761
15-0.242-0.48-3.0650.936
16-0.747-0.631-1.7491.037
17-0.3350.108-0.6080.486
180.632-0.8210.111-0.576
191.087-2.442-0.836-0.665
201.011-4.646-1.407-0.004
21-5.7611.377-3.488-5.347
22-3.5431.157-4.357-0.251
23-0.171-4.4911.135-3.342
24-5.347-3.11.373-5.761
250.026-1.205-3.4880.972
26-0.298-0.597-1.3630.896
Standard thresholds
P-value Threshold
0.001 0.39746
0.0005 1.86386
0.0001 4.92331