MotifTFCP2.H12INVITRO.2.S.C
Gene (human)TFCP2
(GeneCards)
Gene synonyms (human)LSF, SEF
Gene (mouse)Tfcp2
Gene synonyms (mouse)Tcfcp2
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length13
ConsensusnWdAACCGGWWhn
GC content46.52%
Information content (bits; total / per base)13.555 / 1.043
Data sourcesHT-SELEX
Aligned words2475

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.936 0.902 0.891 0.851 0.823 0.787
best 0.984 0.972 0.974 0.959 0.958 0.937
Methyl HT-SELEX, 2 experiments median 0.958 0.934 0.93 0.901 0.886 0.856
best 0.98 0.965 0.969 0.951 0.948 0.924
Non-Methyl HT-SELEX, 3 experiments median 0.829 0.788 0.699 0.684 0.603 0.613
best 0.984 0.972 0.974 0.959 0.958 0.937

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.768 0.511 0.735 0.486
batch 2 0.646 0.15 0.704 0.462
TF superclassImmunoglobulin fold {6} (TFClass)
TF classGrainyhead domain factors {6.7} (TFClass)
TF familyCP2-related {6.7.2} (TFClass)
TF subfamily {6.7.2.0} (TFClass)
TFClass IDTFClass: 6.7.2.0.1
HGNCHGNC:11748
MGIMGI:98509
EntrezGene (human)GeneID:7024
(SSTAR profile)
EntrezGene (mouse)GeneID:21422
(SSTAR profile)
UniProt ID (human)TFCP2_HUMAN
UniProt ID (mouse)TFCP2_MOUSE
UniProt AC (human)Q12800
(TFClass)
UniProt AC (mouse)Q9ERA0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 2
PCM
ACGT
01582.5530.5604.5757.5
021664.5211.5274.5324.5
031231.0224.0664.0356.0
042422.011.09.033.0
052388.00.00.087.0
060.02475.00.00.0
070.02416.00.059.0
0876.00.02399.00.0
090.07.02468.00.0
10878.0111.09.01477.0
11530.0317.0112.01516.0
12505.5784.5273.5911.5
13572.5673.5393.5835.5
PFM
ACGT
010.2350.2140.2440.306
020.6730.0850.1110.131
030.4970.0910.2680.144
040.9790.0040.0040.013
050.9650.00.00.035
060.01.00.00.0
070.00.9760.00.024
080.0310.00.9690.0
090.00.0030.9970.0
100.3550.0450.0040.597
110.2140.1280.0450.613
120.2040.3170.1110.368
130.2310.2720.1590.338
PWM
ACGT
01-0.06-0.153-0.0230.202
020.988-1.067-0.809-0.643
030.686-1.0110.07-0.55
041.362-3.869-4.037-2.877
051.348-5.761-5.761-1.943
06-5.7611.384-5.761-5.761
07-5.7611.36-5.761-2.321
08-2.075-5.7611.353-5.761
09-5.761-4.2391.381-5.761
100.349-1.704-4.0370.868
11-0.154-0.666-1.6950.894
12-0.2010.237-0.8120.386
13-0.0770.085-0.4510.3
Standard thresholds
P-value Threshold
0.001 2.68621
0.0005 4.07546
0.0001 7.069385