MotifTF7L2.H12INVITRO.0.P.D
Gene (human)TCF7L2
(GeneCards)
Gene synonyms (human)TCF4
Gene (mouse)Tcf7l2
Gene synonyms (mouse)Tcf4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length12
ConsensusbbCTTTGAWSYb
GC content43.56%
Information content (bits; total / per base)11.772 / 0.981
Data sourcesChIP-Seq
Aligned words1001

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 21 (126) 0.855 0.939 0.773 0.885 0.832 0.928 3.05 3.803 182.182 504.699
Mouse 6 (37) 0.736 0.933 0.685 0.911 0.733 0.93 2.825 4.42 73.276 261.886
TF superclassOther all-alpha-helical DNA-binding domains {4} (TFClass)
TF classHigh-mobility group (HMG) domain factors {4.1} (TFClass)
TF familyTCF7-related {4.1.3} (TFClass)
TF subfamily {4.1.3.0} (TFClass)
TFClass IDTFClass: 4.1.3.0.3
HGNCHGNC:11641
MGIMGI:1202879
EntrezGene (human)GeneID:6934
(SSTAR profile)
EntrezGene (mouse)GeneID:21416
(SSTAR profile)
UniProt ID (human)TF7L2_HUMAN
UniProt ID (mouse)TF7L2_MOUSE
UniProt AC (human)Q9NQB0
(TFClass)
UniProt AC (mouse)Q924A0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 21 human, 6 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
0181.0325.0369.0226.0
0283.0565.0184.0169.0
034.0883.039.075.0
0417.035.00.0949.0
051.041.09.0950.0
0612.01.03.0985.0
0726.0147.0802.026.0
08862.010.023.0106.0
09301.08.025.0667.0
1027.0508.0451.015.0
11100.0182.056.0663.0
1298.0331.0235.0337.0
PFM
ACGT
010.0810.3250.3690.226
020.0830.5640.1840.169
030.0040.8820.0390.075
040.0170.0350.00.948
050.0010.0410.0090.949
060.0120.0010.0030.984
070.0260.1470.8010.026
080.8610.010.0230.106
090.3010.0080.0250.666
100.0270.5070.4510.015
110.10.1820.0560.662
120.0980.3310.2350.337
PWM
ACGT
01-1.1140.260.386-0.101
02-1.090.811-0.305-0.389
03-3.7841.256-1.822-1.189
04-2.599-1.926-4.9831.328
05-4.526-1.775-3.1571.329
06-2.91-4.526-3.9761.365
07-2.207-0.5271.16-2.207
081.232-3.067-2.321-0.85
090.183-3.254-2.2440.976
10-2.1710.7050.586-2.712
11-0.907-0.316-1.4740.97
12-0.9270.278-0.0620.296
Standard thresholds
P-value Threshold
0.001 4.218115
0.0005 5.217065
0.0001 7.24281