| Motif | TF7L2.H12CORE.0.P.B |
| Gene (human) | TCF7L2 (GeneCards) |
| Gene synonyms (human) | TCF4 |
| Gene (mouse) | Tcf7l2 |
| Gene synonyms (mouse) | Tcf4 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | TF7L2.H12CORE.0.P.B |
| Gene (human) | TCF7L2 (GeneCards) |
| Gene synonyms (human) | TCF4 |
| Gene (mouse) | Tcf7l2 |
| Gene synonyms (mouse) | Tcf4 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 12 |
| Consensus | bbCTTTGAWSYb |
| GC content | 43.56% |
| Information content (bits; total / per base) | 11.772 / 0.981 |
| Data sources | ChIP-Seq |
| Aligned words | 1001 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 21 (126) | 0.855 | 0.939 | 0.773 | 0.885 | 0.832 | 0.928 | 3.05 | 3.803 | 182.182 | 504.699 |
| Mouse | 6 (37) | 0.736 | 0.933 | 0.685 | 0.911 | 0.733 | 0.93 | 2.825 | 4.42 | 73.276 | 261.886 |
| TF superclass | Other all-alpha-helical DNA-binding domains {4} (TFClass) |
| TF class | High-mobility group (HMG) domain factors {4.1} (TFClass) |
| TF family | TCF7-related {4.1.3} (TFClass) |
| TF subfamily | {4.1.3.0} (TFClass) |
| TFClass ID | TFClass: 4.1.3.0.3 |
| HGNC | HGNC:11641 |
| MGI | MGI:1202879 |
| EntrezGene (human) | GeneID:6934 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21416 (SSTAR profile) |
| UniProt ID (human) | TF7L2_HUMAN |
| UniProt ID (mouse) | TF7L2_MOUSE |
| UniProt AC (human) | Q9NQB0 (TFClass) |
| UniProt AC (mouse) | Q924A0 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 21 human, 6 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | TF7L2.H12CORE.0.P.B.pcm |
| PWM | TF7L2.H12CORE.0.P.B.pwm |
| PFM | TF7L2.H12CORE.0.P.B.pfm |
| Alignment | TF7L2.H12CORE.0.P.B.words.tsv |
| Threshold to P-value map | TF7L2.H12CORE.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | TF7L2.H12CORE.0.P.B_jaspar_format.txt |
| MEME format | TF7L2.H12CORE.0.P.B_meme_format.meme |
| Transfac format | TF7L2.H12CORE.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 81.0 | 325.0 | 369.0 | 226.0 |
| 02 | 83.0 | 565.0 | 184.0 | 169.0 |
| 03 | 4.0 | 883.0 | 39.0 | 75.0 |
| 04 | 17.0 | 35.0 | 0.0 | 949.0 |
| 05 | 1.0 | 41.0 | 9.0 | 950.0 |
| 06 | 12.0 | 1.0 | 3.0 | 985.0 |
| 07 | 26.0 | 147.0 | 802.0 | 26.0 |
| 08 | 862.0 | 10.0 | 23.0 | 106.0 |
| 09 | 301.0 | 8.0 | 25.0 | 667.0 |
| 10 | 27.0 | 508.0 | 451.0 | 15.0 |
| 11 | 100.0 | 182.0 | 56.0 | 663.0 |
| 12 | 98.0 | 331.0 | 235.0 | 337.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.081 | 0.325 | 0.369 | 0.226 |
| 02 | 0.083 | 0.564 | 0.184 | 0.169 |
| 03 | 0.004 | 0.882 | 0.039 | 0.075 |
| 04 | 0.017 | 0.035 | 0.0 | 0.948 |
| 05 | 0.001 | 0.041 | 0.009 | 0.949 |
| 06 | 0.012 | 0.001 | 0.003 | 0.984 |
| 07 | 0.026 | 0.147 | 0.801 | 0.026 |
| 08 | 0.861 | 0.01 | 0.023 | 0.106 |
| 09 | 0.301 | 0.008 | 0.025 | 0.666 |
| 10 | 0.027 | 0.507 | 0.451 | 0.015 |
| 11 | 0.1 | 0.182 | 0.056 | 0.662 |
| 12 | 0.098 | 0.331 | 0.235 | 0.337 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.114 | 0.26 | 0.386 | -0.101 |
| 02 | -1.09 | 0.811 | -0.305 | -0.389 |
| 03 | -3.784 | 1.256 | -1.822 | -1.189 |
| 04 | -2.599 | -1.926 | -4.983 | 1.328 |
| 05 | -4.526 | -1.775 | -3.157 | 1.329 |
| 06 | -2.91 | -4.526 | -3.976 | 1.365 |
| 07 | -2.207 | -0.527 | 1.16 | -2.207 |
| 08 | 1.232 | -3.067 | -2.321 | -0.85 |
| 09 | 0.183 | -3.254 | -2.244 | 0.976 |
| 10 | -2.171 | 0.705 | 0.586 | -2.712 |
| 11 | -0.907 | -0.316 | -1.474 | 0.97 |
| 12 | -0.927 | 0.278 | -0.062 | 0.296 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.218115 |
| 0.0005 | 5.217065 |
| 0.0001 | 7.24281 |