TF7L1.H12INVITRO.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TF7L1.H12INVITRO.1.P.C
Gene (human)	TCF7L1 (GeneCards)
Gene synonyms (human)	TCF3
Gene (mouse)	Tcf7l1
Gene synonyms (mouse)	Tcf3
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	12
Consensus	CTTTGWWvTKbd
GC content	34.43%
Information content (bits; total / per base)	11.589 / 0.966
Data sources	ChIP-Seq
Aligned words	1005

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.67	0.681	0.531	0.55	0.707	0.709	1.975	2.039	53.26	62.824
Mouse	1 (7)	0.846	0.849	0.764	0.774	0.848	0.854	3.386	3.454	147.284	163.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.677	0.664	0.574	0.586	0.52	0.544
Overall, 2 experiments	best	0.744	0.711	0.622	0.621	0.545	0.566
Methyl HT-SELEX, 1 experiments	median	0.61	0.616	0.526	0.551	0.496	0.522
Methyl HT-SELEX, 1 experiments	best	0.61	0.616	0.526	0.551	0.496	0.522
Non-Methyl HT-SELEX, 1 experiments	median	0.744	0.711	0.622	0.621	0.545	0.566
Non-Methyl HT-SELEX, 1 experiments	best	0.744	0.711	0.622	0.621	0.545	0.566

TF superclass	Other all-alpha-helical DNA-binding domains {4} (TFClass)
TF class	High-mobility group (HMG) domain factors {4.1} (TFClass)
TF family	TCF7-related {4.1.3} (TFClass)
TF subfamily	{4.1.3.0} (TFClass)
TFClass ID	TFClass: 4.1.3.0.2
HGNC	HGNC:11640
MGI	MGI:1202876
EntrezGene (human)	GeneID:83439 (SSTAR profile)
EntrezGene (mouse)	GeneID:21415 (SSTAR profile)
UniProt ID (human)	TF7L1_HUMAN
UniProt ID (mouse)	TF7L1_MOUSE
UniProt AC (human)	Q9HCS4 (TFClass)
UniProt AC (mouse)	Q9Z1J1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	TF7L1.H12INVITRO.1.P.C.pcm
PWM	TF7L1.H12INVITRO.1.P.C.pwm
PFM	TF7L1.H12INVITRO.1.P.C.pfm
Alignment	TF7L1.H12INVITRO.1.P.C.words.tsv
Threshold to P-value map	TF7L1.H12INVITRO.1.P.C.thr
Motif in other formats
JASPAR format	TF7L1.H12INVITRO.1.P.C_jaspar_format.txt
MEME format	TF7L1.H12INVITRO.1.P.C_meme_format.meme
Transfac format	TF7L1.H12INVITRO.1.P.C_transfac_format.txt
Homer format	TF7L1.H12INVITRO.1.P.C_homer_format_0.001.txt TF7L1.H12INVITRO.1.P.C_homer_format_0.0005.txt TF7L1.H12INVITRO.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	13.0	861.0	28.0	103.0
02	78.0	22.0	1.0	904.0
03	1.0	38.0	15.0	951.0
04	17.0	3.0	14.0	971.0
05	16.0	139.0	801.0	49.0
06	688.0	34.0	54.0	229.0
07	353.0	63.0	79.0	510.0
08	542.0	177.0	212.0	74.0
09	37.0	24.0	18.0	926.0
10	32.0	82.0	706.0	185.0
11	65.0	505.0	119.0	316.0
12	472.0	70.0	87.0	376.0

PFM

	A	C	G	T
01	0.013	0.857	0.028	0.102
02	0.078	0.022	0.001	0.9
03	0.001	0.038	0.015	0.946
04	0.017	0.003	0.014	0.966
05	0.016	0.138	0.797	0.049
06	0.685	0.034	0.054	0.228
07	0.351	0.063	0.079	0.507
08	0.539	0.176	0.211	0.074
09	0.037	0.024	0.018	0.921
10	0.032	0.082	0.702	0.184
11	0.065	0.502	0.118	0.314
12	0.47	0.07	0.087	0.374

PWM

	A	C	G	T
01	-2.844	1.227	-2.141	-0.882
02	-1.155	-2.367	-4.53	1.275
03	-4.53	-1.851	-2.716	1.326
04	-2.603	-3.98	-2.778	1.347
05	-2.658	-0.586	1.155	-1.607
06	1.003	-1.957	-1.513	-0.092
07	0.338	-1.363	-1.142	0.704
08	0.765	-0.347	-0.169	-1.206
09	-1.877	-2.286	-2.551	1.299
10	-2.015	-1.106	1.029	-0.304
11	-1.333	0.695	-0.74	0.228
12	0.627	-1.26	-1.048	0.401

Standard thresholds

P-value	Threshold
0.001	4.312865
0.0005	5.24957
0.0001	7.196465