TF2LX.H12INVIVO.1.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TF2LX.H12INVIVO.1.SM.D
Gene (human)	TGIF2LX (GeneCards)
Gene synonyms (human)	TGIFLX
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	16
Consensus	nndTGACAGCTKdYdn
GC content	49.42%
Information content (bits; total / per base)	15.781 / 0.986
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2234

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.947	0.921	0.89	0.858	0.786	0.768
Overall, 6 experiments	best	0.997	0.996	0.99	0.986	0.965	0.956
Methyl HT-SELEX, 2 experiments	median	0.969	0.955	0.932	0.914	0.862	0.851
Methyl HT-SELEX, 2 experiments	best	0.997	0.996	0.99	0.986	0.965	0.956
Non-Methyl HT-SELEX, 4 experiments	median	0.758	0.74	0.72	0.702	0.666	0.655
Non-Methyl HT-SELEX, 4 experiments	best	0.994	0.992	0.986	0.98	0.948	0.938

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	PKNOX {3.1.4.5} (TFClass)
TFClass ID	TFClass: 3.1.4.5.3
HGNC	HGNC:18570
MGI
EntrezGene (human)	GeneID:90316 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	TF2LX_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8IUE1 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	TF2LX.H12INVIVO.1.SM.D.pcm
PWM	TF2LX.H12INVIVO.1.SM.D.pwm
PFM	TF2LX.H12INVIVO.1.SM.D.pfm
Alignment	TF2LX.H12INVIVO.1.SM.D.words.tsv
Threshold to P-value map	TF2LX.H12INVIVO.1.SM.D.thr
Motif in other formats
JASPAR format	TF2LX.H12INVIVO.1.SM.D_jaspar_format.txt
MEME format	TF2LX.H12INVIVO.1.SM.D_meme_format.meme
Transfac format	TF2LX.H12INVIVO.1.SM.D_transfac_format.txt
Homer format	TF2LX.H12INVIVO.1.SM.D_homer_format_0.001.txt TF2LX.H12INVIVO.1.SM.D_homer_format_0.0005.txt TF2LX.H12INVIVO.1.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	648.5	574.5	490.5	520.5
02	796.25	363.25	436.25	638.25
03	576.0	298.0	370.0	990.0
04	4.0	71.0	0.0	2159.0
05	0.0	0.0	2234.0	0.0
06	2232.0	0.0	0.0	2.0
07	0.0	2234.0	0.0	0.0
08	2234.0	0.0	0.0	0.0
09	0.0	5.0	2218.0	11.0
10	42.0	1840.0	333.0	19.0
11	40.0	226.0	183.0	1785.0
12	269.0	173.0	1484.0	308.0
13	407.0	211.0	295.0	1321.0
14	234.0	1418.0	245.0	337.0
15	1064.5	296.5	520.5	352.5
16	446.25	528.25	616.25	643.25

PFM

	A	C	G	T
01	0.29	0.257	0.22	0.233
02	0.356	0.163	0.195	0.286
03	0.258	0.133	0.166	0.443
04	0.002	0.032	0.0	0.966
05	0.0	0.0	1.0	0.0
06	0.999	0.0	0.0	0.001
07	0.0	1.0	0.0	0.0
08	1.0	0.0	0.0	0.0
09	0.0	0.002	0.993	0.005
10	0.019	0.824	0.149	0.009
11	0.018	0.101	0.082	0.799
12	0.12	0.077	0.664	0.138
13	0.182	0.094	0.132	0.591
14	0.105	0.635	0.11	0.151
15	0.476	0.133	0.233	0.158
16	0.2	0.236	0.276	0.288

PWM

	A	C	G	T
01	0.149	0.028	-0.129	-0.07
02	0.354	-0.428	-0.246	0.133
03	0.031	-0.625	-0.41	0.571
04	-4.549	-2.039	-5.672	1.35
05	-5.672	-5.672	1.384	-5.672
06	1.383	-5.672	-5.672	-4.961
07	-5.672	1.384	-5.672	-5.672
08	1.384	-5.672	-5.672	-5.672
09	-5.672	-4.393	1.377	-3.769
10	-2.546	1.19	-0.515	-3.288
11	-2.593	-0.9	-1.109	1.16
12	-0.727	-1.164	0.975	-0.592
13	-0.315	-0.968	-0.635	0.859
14	-0.865	0.93	-0.82	-0.503
15	0.643	-0.63	-0.07	-0.458
16	-0.224	-0.055	0.098	0.141

Standard thresholds

P-value	Threshold
0.001	1.10046
0.0005	2.63901
0.0001	6.01891