TF2LX.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TF2LX.H12INVIVO.0.SM.D
Gene (human)	TGIF2LX (GeneCards)
Gene synonyms (human)	TGIFLX
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	8
Consensus	nTGACAbn
GC content	46.47%
Information content (bits; total / per base)	9.061 / 1.133
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	3685

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.988	0.984	0.936	0.923	0.825	0.82
Overall, 6 experiments	best	1.0	0.999	0.998	0.997	0.978	0.974
Methyl HT-SELEX, 2 experiments	median	0.99	0.988	0.959	0.951	0.885	0.883
Methyl HT-SELEX, 2 experiments	best	1.0	0.999	0.998	0.997	0.978	0.974
Non-Methyl HT-SELEX, 4 experiments	median	0.821	0.8	0.759	0.752	0.699	0.694
Non-Methyl HT-SELEX, 4 experiments	best	0.999	0.999	0.998	0.997	0.973	0.968

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	TALE-type HD {3.1.4} (TFClass)
TF subfamily	PKNOX {3.1.4.5} (TFClass)
TFClass ID	TFClass: 3.1.4.5.3
HGNC	HGNC:18570
MGI
EntrezGene (human)	GeneID:90316 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	TF2LX_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8IUE1 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	TF2LX.H12INVIVO.0.SM.D.pcm
PWM	TF2LX.H12INVIVO.0.SM.D.pwm
PFM	TF2LX.H12INVIVO.0.SM.D.pfm
Alignment	TF2LX.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	TF2LX.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	TF2LX.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	TF2LX.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	TF2LX.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	TF2LX.H12INVIVO.0.SM.D_homer_format_0.001.txt TF2LX.H12INVIVO.0.SM.D_homer_format_0.0005.txt TF2LX.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1152.75	656.75	818.75	1056.75
02	0.0	0.0	204.0	3481.0
03	14.0	0.0	3671.0	0.0
04	3685.0	0.0	0.0	0.0
05	13.0	3625.0	47.0	0.0
06	3073.0	0.0	612.0	0.0
07	445.0	617.0	1519.0	1104.0
08	891.0	980.0	950.0	864.0

PFM

	A	C	G	T
01	0.313	0.178	0.222	0.287
02	0.0	0.0	0.055	0.945
03	0.004	0.0	0.996	0.0
04	1.0	0.0	0.0	0.0
05	0.004	0.984	0.013	0.0
06	0.834	0.0	0.166	0.0
07	0.121	0.167	0.412	0.3
08	0.242	0.266	0.258	0.234

PWM

	A	C	G	T
01	0.224	-0.338	-0.118	0.137
02	-6.109	-6.109	-1.5	1.328
03	-4.052	-6.109	1.381	-6.109
04	1.385	-6.109	-6.109	-6.109
05	-4.116	1.368	-2.935	-6.109
06	1.203	-6.109	-0.408	-6.109
07	-0.725	-0.4	0.499	0.181
08	-0.033	0.062	0.031	-0.064

Standard thresholds

P-value	Threshold
0.001	5.6913
0.0005	6.47209
0.0001	7.25689