TF2L1.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TF2L1.H12INVIVO.0.PSM.A
Gene (human)	TFCP2L1 (GeneCards)
Gene synonyms (human)	CRTR1, LBP9
Gene (mouse)	Tfcp2l1
Gene synonyms (mouse)	Crtr1, Tcfcp2l1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	20
Consensus	dRdCYRGhhdRRRCYRGhhb
GC content	54.84%
Information content (bits; total / per base)	14.117 / 0.706
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	2 (14)	0.946	0.976	0.896	0.943	0.939	0.967	4.742	5.165	305.087	800.678

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.996	0.993	0.99	0.986	0.968	0.959
Overall, 4 experiments	best	0.997	0.995	0.994	0.991	0.987	0.981
Methyl HT-SELEX, 2 experiments	median	0.997	0.995	0.993	0.989	0.978	0.971
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.994	0.991	0.987	0.981
Non-Methyl HT-SELEX, 2 experiments	median	0.993	0.988	0.986	0.979	0.964	0.952
Non-Methyl HT-SELEX, 2 experiments	best	0.995	0.992	0.989	0.984	0.966	0.956

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	CP2-related {6.7.2} (TFClass)
TF subfamily	{6.7.2.0} (TFClass)
TFClass ID	TFClass: 6.7.2.0.2
HGNC	HGNC:17925
MGI	MGI:2444691
EntrezGene (human)	GeneID:29842 (SSTAR profile)
EntrezGene (mouse)	GeneID:81879 (SSTAR profile)
UniProt ID (human)	TF2L1_HUMAN
UniProt ID (mouse)	TF2L1_MOUSE
UniProt AC (human)	Q9NZI6 (TFClass)
UniProt AC (mouse)	Q3UNW5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	TF2L1.H12INVIVO.0.PSM.A.pcm
PWM	TF2L1.H12INVIVO.0.PSM.A.pwm
PFM	TF2L1.H12INVIVO.0.PSM.A.pfm
Alignment	TF2L1.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	TF2L1.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	TF2L1.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	TF2L1.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	TF2L1.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	TF2L1.H12INVIVO.0.PSM.A_homer_format_0.001.txt TF2L1.H12INVIVO.0.PSM.A_homer_format_0.0005.txt TF2L1.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	341.0	128.0	387.0	142.0
02	568.0	60.0	253.0	117.0
03	423.0	36.0	319.0	220.0
04	2.0	942.0	53.0	1.0
05	144.0	537.0	7.0	310.0
06	339.0	3.0	590.0	66.0
07	2.0	33.0	962.0	1.0
08	203.0	298.0	46.0	451.0
09	120.0	363.0	91.0	424.0
10	320.0	15.0	252.0	411.0
11	222.0	66.0	693.0	17.0
12	734.0	38.0	165.0	61.0
13	507.0	3.0	292.0	196.0
14	0.0	965.0	31.0	2.0
15	92.0	571.0	0.0	335.0
16	348.0	5.0	581.0	64.0
17	4.0	37.0	956.0	1.0
18	218.0	280.0	49.0	451.0
19	142.0	291.0	116.0	449.0
20	155.0	263.0	170.0	410.0

PFM

	A	C	G	T
01	0.342	0.128	0.388	0.142
02	0.569	0.06	0.254	0.117
03	0.424	0.036	0.32	0.22
04	0.002	0.944	0.053	0.001
05	0.144	0.538	0.007	0.311
06	0.34	0.003	0.591	0.066
07	0.002	0.033	0.964	0.001
08	0.203	0.299	0.046	0.452
09	0.12	0.364	0.091	0.425
10	0.321	0.015	0.253	0.412
11	0.222	0.066	0.694	0.017
12	0.735	0.038	0.165	0.061
13	0.508	0.003	0.293	0.196
14	0.0	0.967	0.031	0.002
15	0.092	0.572	0.0	0.336
16	0.349	0.005	0.582	0.064
17	0.004	0.037	0.958	0.001
18	0.218	0.281	0.049	0.452
19	0.142	0.292	0.116	0.45
20	0.155	0.264	0.17	0.411

PWM

	A	C	G	T
01	0.311	-0.661	0.437	-0.558
02	0.819	-1.404	0.014	-0.75
03	0.525	-1.896	0.244	-0.125
04	-4.211	1.323	-1.524	-4.523
05	-0.545	0.763	-3.36	0.216
06	0.305	-3.973	0.857	-1.311
07	-4.211	-1.979	1.344	-4.523
08	-0.205	0.177	-1.661	0.589
09	-0.725	0.373	-0.997	0.527
10	0.247	-2.709	0.01	0.496
11	-0.116	-1.311	1.017	-2.596
12	1.075	-1.844	-0.41	-1.388
13	0.706	-3.973	0.156	-0.239
14	-4.98	1.348	-2.038	-4.211
15	-0.986	0.824	-4.98	0.293
16	0.331	-3.62	0.841	-1.341
17	-3.781	-1.87	1.338	-4.523
18	-0.134	0.115	-1.6	0.589
19	-0.558	0.153	-0.758	0.585
20	-0.472	0.052	-0.38	0.494

Standard thresholds

P-value	Threshold
0.001	3.27571
0.0005	4.45111
0.0001	6.85681