MotifTF2L1.H12INVITRO.0.PSM.A
Gene (human)TFCP2L1
(GeneCards)
Gene synonyms (human)CRTR1, LBP9
Gene (mouse)Tfcp2l1
Gene synonyms (mouse)Crtr1, Tcfcp2l1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length20
ConsensusnddCYRGhbndWACCGGWWn
GC content53.12%
Information content (bits; total / per base)15.494 / 0.775
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9063

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (14) 0.933 0.975 0.878 0.938 0.908 0.957 4.513 4.919 292.31 784.252

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.997 0.996 0.993 0.99 0.974 0.967
best 0.998 0.997 0.996 0.994 0.989 0.985
Methyl HT-SELEX, 2 experiments median 0.998 0.997 0.995 0.993 0.983 0.978
best 0.998 0.997 0.996 0.994 0.989 0.985
Non-Methyl HT-SELEX, 2 experiments median 0.995 0.992 0.989 0.983 0.968 0.958
best 0.997 0.995 0.992 0.988 0.97 0.962
TF superclassImmunoglobulin fold {6} (TFClass)
TF classGrainyhead domain factors {6.7} (TFClass)
TF familyCP2-related {6.7.2} (TFClass)
TF subfamily {6.7.2.0} (TFClass)
TFClass IDTFClass: 6.7.2.0.2
HGNCHGNC:17925
MGIMGI:2444691
EntrezGene (human)GeneID:29842
(SSTAR profile)
EntrezGene (mouse)GeneID:81879
(SSTAR profile)
UniProt ID (human)TF2L1_HUMAN
UniProt ID (mouse)TF2L1_MOUSE
UniProt AC (human)Q9NZI6
(TFClass)
UniProt AC (mouse)Q3UNW5
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
012671.51896.52588.51906.5
024413.5947.51923.51778.5
034363.0353.01992.02355.0
0465.08034.0705.0259.0
05441.05813.0259.02550.0
062732.0229.05661.0441.0
07186.0644.08183.050.0
081759.02750.0263.04291.0
09875.02425.0943.04820.0
101652.02320.02281.02810.0
113463.0846.03516.01238.0
126647.0221.0860.01335.0
136967.012.091.01993.0
140.09039.022.02.0
1521.07713.00.01329.0
161526.08.07487.042.0
175.0123.08933.02.0
182087.0778.036.06162.0
191519.751430.75632.755479.75
201944.02572.01749.02798.0
PFM
ACGT
010.2950.2090.2860.21
020.4870.1050.2120.196
030.4810.0390.220.26
040.0070.8860.0780.029
050.0490.6410.0290.281
060.3010.0250.6250.049
070.0210.0710.9030.006
080.1940.3030.0290.473
090.0970.2680.1040.532
100.1820.2560.2520.31
110.3820.0930.3880.137
120.7330.0240.0950.147
130.7690.0010.010.22
140.00.9970.0020.0
150.0020.8510.00.147
160.1680.0010.8260.005
170.0010.0140.9860.0
180.230.0860.0040.68
190.1680.1580.070.605
200.2140.2840.1930.309
PWM
ACGT
010.165-0.1780.133-0.172
020.666-0.87-0.164-0.242
030.655-1.854-0.1290.039
04-3.5181.265-1.165-2.161
05-1.6320.942-2.1610.118
060.187-2.2830.915-1.632
07-2.489-1.2551.283-3.77
08-0.2530.194-2.1460.638
09-0.950.068-0.8750.754
10-0.3160.0240.0070.215
110.424-0.9830.439-0.604
121.076-2.318-0.967-0.528
131.123-5.068-3.191-0.128
14-6.9031.383-4.537-6.273
15-4.5791.224-6.903-0.533
16-0.395-5.3971.195-3.936
17-5.742-2.8961.371-6.273
18-0.082-1.067-4.0821.0
19-0.399-0.459-1.2730.883
20-0.1530.127-0.2590.211
Standard thresholds
P-value Threshold
0.001 2.32946
0.0005 3.67726
0.0001 6.39946