TF2L1.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TF2L1.H12INVITRO.0.PSM.A
Gene (human)	TFCP2L1 (GeneCards)
Gene synonyms (human)	CRTR1, LBP9
Gene (mouse)	Tfcp2l1
Gene synonyms (mouse)	Crtr1, Tcfcp2l1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	20
Consensus	nddCYRGhbndWACCGGWWn
GC content	53.12%
Information content (bits; total / per base)	15.494 / 0.775
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9063

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	2 (14)	0.933	0.975	0.878	0.938	0.908	0.957	4.513	4.919	292.31	784.252

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.997	0.996	0.993	0.99	0.974	0.967
Overall, 4 experiments	best	0.998	0.997	0.996	0.994	0.989	0.985
Methyl HT-SELEX, 2 experiments	median	0.998	0.997	0.995	0.993	0.983	0.978
Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.996	0.994	0.989	0.985
Non-Methyl HT-SELEX, 2 experiments	median	0.995	0.992	0.989	0.983	0.968	0.958
Non-Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.992	0.988	0.97	0.962

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	CP2-related {6.7.2} (TFClass)
TF subfamily	{6.7.2.0} (TFClass)
TFClass ID	TFClass: 6.7.2.0.2
HGNC	HGNC:17925
MGI	MGI:2444691
EntrezGene (human)	GeneID:29842 (SSTAR profile)
EntrezGene (mouse)	GeneID:81879 (SSTAR profile)
UniProt ID (human)	TF2L1_HUMAN
UniProt ID (mouse)	TF2L1_MOUSE
UniProt AC (human)	Q9NZI6 (TFClass)
UniProt AC (mouse)	Q3UNW5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	TF2L1.H12INVITRO.0.PSM.A.pcm
PWM	TF2L1.H12INVITRO.0.PSM.A.pwm
PFM	TF2L1.H12INVITRO.0.PSM.A.pfm
Alignment	TF2L1.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	TF2L1.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	TF2L1.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	TF2L1.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	TF2L1.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	TF2L1.H12INVITRO.0.PSM.A_homer_format_0.001.txt TF2L1.H12INVITRO.0.PSM.A_homer_format_0.0005.txt TF2L1.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2671.5	1896.5	2588.5	1906.5
02	4413.5	947.5	1923.5	1778.5
03	4363.0	353.0	1992.0	2355.0
04	65.0	8034.0	705.0	259.0
05	441.0	5813.0	259.0	2550.0
06	2732.0	229.0	5661.0	441.0
07	186.0	644.0	8183.0	50.0
08	1759.0	2750.0	263.0	4291.0
09	875.0	2425.0	943.0	4820.0
10	1652.0	2320.0	2281.0	2810.0
11	3463.0	846.0	3516.0	1238.0
12	6647.0	221.0	860.0	1335.0
13	6967.0	12.0	91.0	1993.0
14	0.0	9039.0	22.0	2.0
15	21.0	7713.0	0.0	1329.0
16	1526.0	8.0	7487.0	42.0
17	5.0	123.0	8933.0	2.0
18	2087.0	778.0	36.0	6162.0
19	1519.75	1430.75	632.75	5479.75
20	1944.0	2572.0	1749.0	2798.0

PFM

	A	C	G	T
01	0.295	0.209	0.286	0.21
02	0.487	0.105	0.212	0.196
03	0.481	0.039	0.22	0.26
04	0.007	0.886	0.078	0.029
05	0.049	0.641	0.029	0.281
06	0.301	0.025	0.625	0.049
07	0.021	0.071	0.903	0.006
08	0.194	0.303	0.029	0.473
09	0.097	0.268	0.104	0.532
10	0.182	0.256	0.252	0.31
11	0.382	0.093	0.388	0.137
12	0.733	0.024	0.095	0.147
13	0.769	0.001	0.01	0.22
14	0.0	0.997	0.002	0.0
15	0.002	0.851	0.0	0.147
16	0.168	0.001	0.826	0.005
17	0.001	0.014	0.986	0.0
18	0.23	0.086	0.004	0.68
19	0.168	0.158	0.07	0.605
20	0.214	0.284	0.193	0.309

PWM

	A	C	G	T
01	0.165	-0.178	0.133	-0.172
02	0.666	-0.87	-0.164	-0.242
03	0.655	-1.854	-0.129	0.039
04	-3.518	1.265	-1.165	-2.161
05	-1.632	0.942	-2.161	0.118
06	0.187	-2.283	0.915	-1.632
07	-2.489	-1.255	1.283	-3.77
08	-0.253	0.194	-2.146	0.638
09	-0.95	0.068	-0.875	0.754
10	-0.316	0.024	0.007	0.215
11	0.424	-0.983	0.439	-0.604
12	1.076	-2.318	-0.967	-0.528
13	1.123	-5.068	-3.191	-0.128
14	-6.903	1.383	-4.537	-6.273
15	-4.579	1.224	-6.903	-0.533
16	-0.395	-5.397	1.195	-3.936
17	-5.742	-2.896	1.371	-6.273
18	-0.082	-1.067	-4.082	1.0
19	-0.399	-0.459	-1.273	0.883
20	-0.153	0.127	-0.259	0.211

Standard thresholds

P-value	Threshold
0.001	2.32946
0.0005	3.67726
0.0001	6.39946